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Chromatin Assembly Factor 1, Subunit B (p60) Proteins (CHAF1B)

Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. Additionally we are shipping CHAF1B Antibodies (43) and CHAF1B Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHAF1B 8208 Q13112
CHAF1B 110749 Q9D0N7
Rat CHAF1B CHAF1B 288242  
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Top CHAF1B Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CHAF1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) Interaction Partners

Human Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) interaction partners

  1. All the evaluated malignant tumors showed CAF-1 p60 overexpression, confirming the emerging role of CAF-1 p60 as a new proliferation and prognostic marker for cancer.

  2. The levels of the EDNRB (show EDNRB Proteins), HJURP (show HJURP Proteins) and p60/CAF-1 proteins were strongly associated with overall survival in high-grade gliomas patients (p<0.001, p<0.001 and p=0.002, respectively), whereas the one of PDLI4 (show PDLIM4 Proteins) was not (P=0.11).

  3. Overexpression of CAF-1/p60, on histological and/or cytological samples, characterizes malignant salivary gland tumours with aggressive behaviour

  4. CAF-1 is a proliferation marker in various malignant tumours with prognostic value in renal, endometrial and cervical carcinomas, which supports the value of CAF-1 as a clinical marker of cancer progression.

  5. Chromatin Assembly Factor-1/p60 may have a role in progression and metastasis of melanoma

  6. model is proposed in which the synergism between hAsf1 (show ASF1A Proteins) and CAF-1 for nucleosome formation during DNA repair is achieved through a transient physical interaction allowing histone delivery from Asf1 (show SRSF1 Proteins) to CAF-1 [asf1(anti-silencing function 1 (show ASF1A Proteins))]

  7. These data identify chromatin assembly factor 1 (show RBBP4 Proteins) as an essential factor not only for S-phase-specific chromatin assembly but also for proliferating cell viability.

  8. Downregulated protein level of CAF-1 p60 in adult brain of patients with Down syndrome (DS) in contrast to Alzheimer's disease indicates that it can be considered specific for changes in DS.

  9. The N- & C-terminal regions of ASF1a (show ASF1A Proteins) and ASF1b (show ASF1B Proteins) determine the different affinities of these two proteins for HIRA (show HIRA Proteins), by contacting regions outside the HIRA (show HIRA Proteins) B domain. CAF-1 p60 also uses B domain-like motifs for binding to ASF1a (show ASF1A Proteins), thereby competing with HIRA (show HIRA Proteins).

  10. overexpression of CAF-1/p60 characterized prostatic cancers with a worse prognosis

CHAF1B Protein Profile

Protein Summary

Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.

Gene names and symbols associated with CHAF1B

  • chromatin assembly factor 1, subunit B (p60) (CHAF1B)
  • chromatin assembly factor 1, subunit B (p60) (chaf1b)
  • chromatin assembly factor 1, subunit B (p60) (LOC100223590)
  • chromatin assembly factor 1, subunit B (chaf1b)
  • chromatin assembly factor 1, subunit B (p60) (Chaf1b)
  • 2600017H24Rik protein
  • C76145 protein
  • caf-1 protein
  • CAF-1P60 protein
  • CAF-I p60 protein
  • CAF-Ip60 protein
  • CAF1 protein
  • CAF1A protein
  • CAF1P60 protein
  • CHAF1B protein
  • MPHOSPH7 protein
  • MPP7 protein
  • wu:fd07c09 protein
  • wu:fe36g06 protein
  • wu:fv38g09 protein
  • zgc:56096 protein

Protein level used designations for CHAF1B

chromatin assembly factor 1, subunit B (p60) , chromatin assembly factor 1 subunit B , chromatin assembly factor 1 subunit B-like , fe36g06 , CAF-1 subunit B , CAF-I 60 kDa subunit , CAF-I p60 , M-phase phosphoprotein 7 , chromatin assembly factor I p60 subunit , human chromatin assembly factor-I p60 subunit , chromatin assembly factor-1 p60 subunit , CAF-Ip60 , chromatin assembly factor-1p60

GENE ID SPECIES
470084 Pan troglodytes
695206 Macaca mulatta
100127620 Xenopus (Silurana) tropicalis
100223590 Taeniopygia guttata
100393026 Callithrix jacchus
100454892 Pongo abelii
100483422 Ailuropoda melanoleuca
100513568 Sus scrofa
100022083 Monodelphis domestica
100061263 Equus caballus
406285 Danio rerio
8208 Homo sapiens
110749 Mus musculus
779086 Xenopus laevis
418514 Gallus gallus
487750 Canis lupus familiaris
511654 Bos taurus
288242 Rattus norvegicus
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