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CHD3 encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. Additionally we are shipping CHD3 Antibodies (86) and CHD3 Proteins (5) and many more products for this protein.
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dCHD3 exists as a monomer
CHD3 and CHD4 (show CHD4 ELISA Kits) exhibit distinct nuclear localization patterns in unperturbed cells, revealing a subset of specific target genes.
Mutations in CHD3 gene is associated with cutaneous T cell lymphoma and Sezary syndrome.
CHD3 was confirmed to interact with NES1 (show KLK10 ELISA Kits) in NS2, and a disruption to this interaction by mutation in NES1 (show KLK10 ELISA Kits) significantly delayed viral vRNPs export and viral propagation.
CHD3.1 and ACF1-SNF2H display counteractive activities but similar histone affinities.
In this study, the chromatin remodeler chromodomain helicase DNA binding (CHD3) protein is identified as an important component of the initial repression of the herpesvirus genome.
effect of progressive C-terminal deletions of CHD3, which indicated that sequences required for repression of PS1 (show PSEN1 ELISA Kits) lie between amino acids 1955 and 1877
Pericentrin (show PCNT ELISA Kits) forms complexes with CHD3 and CHD4 (show CHD4 ELISA Kits), but a distinct CHD3-pericentrin (show PCNT ELISA Kits) complex is required for centrosomal anchoring of pericentrin (show PCNT ELISA Kits)/gamma-tubulin (show TUBG1 ELISA Kits) and for centrosome integrity.
UV radiation regulates Mi-2 (show CHD4 ELISA Kits) through protein translation and stability
results suggest that ZFH/Chd3 might play an important role in tooth root development and subsequent cementogenesis.
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
, chromodomain helicase DNA binding protein 3
, similar to CHD3
, chromodomain-helicase-DNA-binding protein 3-like
, ATP-dependent helicase CHD3
, chromodomain-helicase-DNA-binding protein 3
, mi-2 autoantigen 240 kDa protein
, zinc finger helicase
, zinc-finger helicase (Snf2-like)
, Mi-2 alpha
, CHD3-like protein