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anti-Chromosome 14 Open Reading Frame 49 (C14orf49) Antibodies

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Additionally we are shipping Nesprin3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C14orf49 161176 Q6ZMZ3
C14orf49 212073 Q4FZC9
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Top anti-Nesprin3 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB SYNE3 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hodgkin lymphoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SYNE3 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. SYNE3 Antibody (C-term) western blot analysis in mouse spleen cell line lysates (35µg/lane).This demonstrates the SYNE3 antibody detected the SYNE3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using C14orf49 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB SYNE3 antibody (C-term) (ABIN654777) immunohistochemistry analysis in formalin fixed and paraffin embedded human hodgkin lymphoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated IHC (fro), WB 1000 μL Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of SYNE3 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of SYNE3 expression in HepG2 (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

C14orf49 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


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Mouse (Murine)
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Top referenced anti-Nesprin3 Antibodies

  1. Human Polyclonal Nesprin3 Primary Antibody for EIA, IHC (p) - ABIN953651 : Nery, Zeng, Niland, Hewett, Farley, Irimia, Li, Wiche, Sonnenberg, Breakefield: TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. in Journal of cell science 2008 (PubMed)
    Show all 4 references for ABIN953651

  2. Human Polyclonal Nesprin3 Primary Antibody for ELISA, WB - ABIN1535082 : Heilig, Eckenberg, Petit, Fonknechten, Da Silva, Cattolico, Levy, Barbe, de Berardinis, Ureta-Vidal, Pelletier, Vico, Anthouard, Rowen, Madan, Qin, Sun, Du, Pepin, Artiguenave, Robert, Cruaud, Brüls et al.: The DNA sequence and analysis of human chromosome 14. ... in Nature 2003 (PubMed)

More Antibodies against Nesprin3 Interaction Partners

Human Chromosome 14 Open Reading Frame 49 (C14orf49) interaction partners

  1. nesprin-3 regulates vascular endothelial cell shape, perinuclear cytoskeletal architecture, and important aspects of flow-mediated mechanotransduction.

  2. association with human nesprin-3 appeared to be stronge (show TOR1A Antibodies)r for torsinADeltaE than for torsinA. TorsinA also (show TOR1A Antibodies)associated with the KASH domains of nesprin-1 and -2

Mouse (Murine) Chromosome 14 Open Reading Frame 49 (C14orf49) interaction partners

  1. Nesprin-3 is critical for the localization of plectin (show PLEC Antibodies) to the nuclear perimeter of Sertoli cells.

  2. Data indicate roles for linkers of nucleus to cytoskeleton (LINC) molecules nesprin2giant and nesprin3, which anchor actin cap fibers to the nucleus.

  3. plectin (show PLEC Antibodies) binds to the integrin alpha6beta4 at the cell surface and to nesprin-3 at the ONM in keratinocytes.

  4. Data support a model in which the actin cytoskeleton influences the binding of plectin (show PLEC Antibodies) dimers to dimers of nesprin-3alpha, which in turn are retained at the nuclear envelope through an interaction with Sun proteins.

  5. Mouse nesprin-3alpha co-immunoprecipitated with torsinA (show TOR1A Antibodies) and this involved the C-terminal region of torsinA (show TOR1A Antibodies) and the KASH domain of nesprin-3alpha.

Nesprin3 (C14orf49) Antigen Profile

Protein Summary

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

Gene names and symbols associated with C14orf49

  • chromosome 14 open reading frame 49 (C14orf49) antibody
  • spectrin repeat containing, nuclear envelope family member 3 (SYNE3) antibody
  • spectrin repeat containing, nuclear envelope family member 3 (Syne3) antibody
  • 4831426I19Rik antibody
  • C14orf49 antibody
  • Nesp3 antibody
  • nesprin-3 antibody
  • NET53 antibody

Protein level used designations for C14orf49

chromosome 14 open reading frame 49 , nesprin-3 , nuclear envelope spectrin repeat protein 3

GENE ID SPECIES
423439 Gallus gallus
161176 Homo sapiens
212073 Mus musculus
Selected quality suppliers for anti-Nesprin3 (C14orf49) Antibodies
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