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Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Additionally we are shipping Chromosome 17 Open Reading Frame 37 Proteins (7) and many more products for this protein.
Showing 10 out of 74 products:
Human Polyclonal C17orf37 Primary Antibody for WB - ABIN529648
Dasgupta, Wasson, Rauniyar, Prokai, Borejdo, Vishwanatha: Novel gene C17orf37 in 17q12 amplicon promotes migration and invasion of prostate cancer cells. in Oncogene 2009
Show all 2 references for ABIN529648
Human Monoclonal C17orf37 Primary Antibody for ELISA, WB - ABIN949731
Dasgupta, Cushman, Kpetemey, Casey, Vishwanatha: Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis. in The Journal of biological chemistry 2011
Show all 2 references for ABIN949731
Human Polyclonal C17orf37 Primary Antibody for EIA, WB - ABIN492835
Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002
In conclusion, this study revealed that miR-26b suppresses NSCLC metastasis by targeting MIEN1 via NF-kappaB/MMP-9/VEGF pathways, implicating a potential prognostic biomarker and therapeutic target for NSCLC treatment.
MIEN1, a novel interactor of Annexin A2 (show ANXA2 Antibodies), promotes tumor cell migration by enhancing AnxA2 (show ANXA2 Antibodies) cell surface expression.
MIEN1 expression not only positively correlates with oral cancer progression but also seems to be a critical molecular determinant in migration and invasion of oral cancer cells.
C35 might serve as a biomarker or therapeutic target for management of colorectal cancer.
While MIEN1 is a direct target of miR (show MLXIP Antibodies)-940, miR (show MLXIP Antibodies)-940 alters MIEN1 RNA.
results suggest that DeltaNp73 might cooperate with C35 to promote tumour progression and contribute to cisplatin resistance in ovarian cancer cells.
Results suggest that MIEN1 may have an important regulatory role in phosphorylation of AKT (show AKT1 Antibodies) with its redox potential.
prenylation is required for the function of the C17orf37 protein in cancer cells
Inhibition of C35 gene expression by small interfering RNA induces apoptosis of breast cancer cells.
Data strongly suggest C17orf37 overexpression in prostate cancer functionally enhances migration and invasion of tumor cells, and is an important target for cancer therapy.
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process (By similarity).
hypothetical protein LOC548750
, hypothetical protein LOC100049740
, HBV X-transactivated gene 4 protein
, HBV XAg-transactivated protein 4
, protein C17orf37
, protein C17orf37 homolog