C17orf37 antibody

Catalog No. ABIN7073498

Product Details anti-C17orf37 Antibody

Target: C17orf37 (Chromosome 17 Open Reading Frame 37 (C17orf37))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C17orf37 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse XTP4

Application Details

Application Notes: WB (M,R) 1:200-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for C17orf37

Target: C17orf37 (Chromosome 17 Open Reading Frame 37 (C17orf37))

Alternative Name: XTP4 (C17orf37 Products)

Synonyms: C17orf37 antibody, C35 antibody, ORB3 antibody, RDX12 antibody, XTP4 antibody, C19H17orf37 antibody, 1810046J19Rik antibody, AI463380 antibody, Rdx12 antibody, migration and invasion enhancer 1 antibody, migration and invasion enhancer 1 S homeolog antibody, mien1 antibody, mien1.S antibody, MIEN1 antibody, Mien1 antibody

Background: During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail.

Molecular Weight: 12 kDa

Gene ID: 103742

NCBI Accession: NP_079835

UniProt: Q9CQ86

Pathways: Cell RedoxHomeostasis