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Chromosome 18 Open Reading Frame 8 Proteins (C18orf8)

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping C18orf8 Antibodies (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C18orf8 29919 Q96DM3
C18orf8 76482 Q8VC42
Rat C18orf8 C18orf8 291784  
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Top C18orf8 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
$7,759.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

C18orf8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Chromosome 18 Open Reading Frame 8 (C18orf8) Interaction Partners

Human Chromosome 18 Open Reading Frame 8 (C18orf8) interaction partners

  1. ChIP studies showed that the S100A4 (show S100A4 Proteins) protein binds to the GDF15 (show GDF15 Proteins) promoter, implicating S100A4 (show S100A4 Proteins) in GDF15 (show GDF15 Proteins) regulation at the transcriptional level.

  2. Study compared the diagnostic utility of GDF-15 (show GDF15 Proteins) with FGF-21 (show FGF21 Proteins) in an adult mitochondrial disease cohort. GDF-15 (show GDF15 Proteins) outperforms FGF-21 (show FGF21 Proteins) as an indicator of mitochondrial diseases. GDF-15 (show GDF15 Proteins) is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 (show FGF21 Proteins) seems to be more indicative of mitochondrial disease when muscle manifestations are present

  3. MIC1/GDF15 (show GDF15 Proteins) may have a role in monitoring bone metastases

  4. GDF15 (show GDF15 Proteins) contributes to fibroblast activation and may be a novel functional secreted molecule for diffuse gastric cancer progression

  5. MIC-1 was involved in the development of MBD in patients with MM by promoting the osteoclastic differentiation of PBMNCs by activating the RANKL-Erk1/2 signaling pathway.

  6. The level of MIC-1 of Non-small Cell Lung Cancer patients was significantly higher than that of controls (P<0.001) and benign pulmonary disease patients.

  7. association of elevated GDF-15 (show GDF15 Proteins) levels with increased risk of mortality in patients with heart failure [meta-analysis]

  8. MIC-1/GDF15 (show GDF15 Proteins) may provide a link between childhood obesity and cardio metabolic complications that will occur in time course.

  9. GDF-15 (show GDF15 Proteins), sST2 (show SSTR2 Proteins), and hs-TnI (show TNNI2 Proteins) are associated with incident cardiovascular disease and heart failure

  10. GDF15 (show GDF15 Proteins) was statistically significantly higher in patients with nasal polyps than in controls.

C18orf8 Protein Profile

Protein Summary

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with C18orf8

  • chromosome 18 open reading frame 8 (C18orf8)
  • chromosome 18 open reading frame 8 (c18orf8)
  • growth differentiation factor 15 (GDF15)
  • RIKEN cDNA 3110002H16 gene (3110002H16Rik)
  • similar to RIKEN cDNA 2400010D15 (RGD1311805)
  • 2400010D15Rik protein
  • C18orf8 protein
  • GDF-15 protein
  • HsT2591 protein
  • MIC-1 protein
  • Mic1 protein
  • NAG-1 protein
  • PDF protein
  • PLAB protein
  • PTGFB protein

Protein level used designations for C18orf8

chromosome 18 open reading frame 8 , hypothetical protein LOC100124886 , hypothetical protein LOC100137621 , colon cancer-associated protein Mic1 , uncharacterized protein C18orf8 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , colon cancer-associated protein Mic1 homolog , uncharacterized protein C18orf8 homolog , uncharacterized protein LOC291784

GENE ID SPECIES
421075 Gallus gallus
100124886 Xenopus (Silurana) tropicalis
100137621 Xenopus laevis
29919 Homo sapiens
9518 Homo sapiens
76482 Mus musculus
291784 Rattus norvegicus
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