Chromosome 18 Open Reading Frame 8 Proteins (C18orf8)

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping C18orf8 Antibodies (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C18orf8 29919 Q96DM3
C18orf8 76482 Q8VC42
Rat C18orf8 C18orf8 291784  
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Top C18orf8 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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C18orf8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Chromosome 18 Open Reading Frame 8 (C18orf8) Interaction Partners

Human Chromosome 18 Open Reading Frame 8 (C18orf8) interaction partners

  1. PPIX concentrations correlated with both growth differentiation factor (GDF) 15 (show GDF15 Proteins) (p = 0.012) and male gender (p = 0.015).

  2. Data show that growth differentiation factor 15 (GDF15 (show GDF15 Proteins)) knockdown significantly inhibited the growth and metastasis of cancer stem-like sphere cells (SCs (show TWIST1 Proteins)) through AKT (show AKT1 Proteins)/GSK-3beta/beta-catenin (show CTNNB1 Proteins) pathway suppression.

  3. epithelial restitution was promoted by enhanced NAG-1 (show GDF15 Proteins) expression and subsequent enterocyte locomotion during the early wound-healing process

  4. serum GDF15 (show GDF15 Proteins) may be a useful diagnostic and prognostic biomarker for colorectal cancer.

  5. These findings highlight an important contribution of GDF15 (show GDF15 Proteins) in promoting airway epithelial senescence upon cigarette smoke exposure.

  6. The results of this study, including a robust induction of GDF-15 (show GDF15 Proteins) expression by several external factors known to elevate IOP, and rGDF-15-induced increase in contractility, cell adhesion, and the levels of ECM (show MMRN1 Proteins) proteins and alphaSMA (show ACTA2 Proteins) in TM cells

  7. GDF-15 (show GDF15 Proteins) captures distinct aspects of cardiovascular disease development, progression, and prognosis, which are not represented by clinical risk predictors and other biomarkers. The usefulness of GDF-15 (show GDF15 Proteins) to guide management decisions and discover new treatment targets should be further explored.

  8. In stable Coronary Heart Disease, GDF-15 (show GDF15 Proteins) was independently associated with cardiovascular (CV), non-CV, and cancer mortality, as well as with MI and stroke. When also adjusting for other prognostic biomarkers, the associations to all fatal and nonfatal events were maintained except for MI. Information on GDF-15 (show GDF15 Proteins), therefore, might be helpful when assessing the risk of adverse outcomes in patients with stable CHD (show CHDH Proteins).

  9. Impaired glucose tolerance is associated with increased GDF-15 (show GDF15 Proteins) levels even in the absence of anemia

  10. GDF15 (show GDF15 Proteins) is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (show INS Proteins) resistance.

C18orf8 Protein Profile

Protein Summary

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with C18orf8

  • chromosome 18 open reading frame 8 (C18orf8)
  • chromosome 18 open reading frame 8 (c18orf8)
  • growth differentiation factor 15 (GDF15)
  • RIKEN cDNA 3110002H16 gene (3110002H16Rik)
  • similar to RIKEN cDNA 2400010D15 (RGD1311805)
  • 2400010D15Rik protein
  • C18orf8 protein
  • GDF-15 protein
  • HsT2591 protein
  • MIC-1 protein
  • Mic1 protein
  • NAG-1 protein
  • PDF protein
  • PLAB protein
  • PTGFB protein

Protein level used designations for C18orf8

chromosome 18 open reading frame 8 , hypothetical protein LOC100124886 , hypothetical protein LOC100137621 , colon cancer-associated protein Mic1 , uncharacterized protein C18orf8 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , colon cancer-associated protein Mic1 homolog , uncharacterized protein C18orf8 homolog , uncharacterized protein LOC291784

GENE ID SPECIES
421075 Gallus gallus
100124886 Xenopus (Silurana) tropicalis
100137621 Xenopus laevis
29919 Homo sapiens
9518 Homo sapiens
76482 Mus musculus
291784 Rattus norvegicus
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