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May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.. Additionally we are shipping Chromosome 5 Open Reading Frame 39 Antibodies (24) and many more products for this protein.
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Data highlighted the crucial role of AXIIR in reducing Mum2C cell viability through inducing apoptosis, while autophagy played a protective role in this process.
these subsequent effects might be via suppressing the expression of matrix metalloproteinase 2 (show MMP2 Proteins) and matrix metalloproteinase 9 (show MMP9 Proteins). ... AXIIR participates in angiogenesis, and may be a potential therapeutic target for angiogenesis related diseases
AXIIR acts as a novel inducer of apoptosis in human cells, partially through activating Caspase-8 (show CASP8 Proteins).
Results show that AXII and AXIIR play important roles in multiple myeloma (MM) and that targeting the AXII/AXIIR axis may be a novel therapeutic approach for MM.
analysis of the annexin II receptor on human marrow stromal cells
annexin II and its receptor axis play a central role in prostate cancer metastasis, and prostate cancer utilizes the hematopoietic stem cell homing mechanisms to gain access to the niche.
May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.
annexin II receptor
, annexin-2 receptor