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May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.. Additionally we are shipping Chromosome 5 Open Reading Frame 39 Proteins (2) and many more products for this protein.
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Human Polyclonal C5orf39 Primary Antibody for WB - ABIN2785711
Lu, Maeda, Reddy, Kurihara, Leach, Anderson, Roodman: Cloning and characterization of the annexin II receptor on human marrow stromal cells. in The Journal of biological chemistry 2006
Data highlighted the crucial role of AXIIR in reducing Mum2C cell viability through inducing apoptosis, while autophagy played a protective role in this process.
these subsequent effects might be via suppressing the expression of matrix metalloproteinase 2 (show MMP2 Antibodies) and matrix metalloproteinase 9 (show MMP9 Antibodies). ... AXIIR participates in angiogenesis, and may be a potential therapeutic target for angiogenesis related diseases
AXIIR acts as a novel inducer of apoptosis in human cells, partially through activating Caspase-8 (show CASP8 Antibodies).
Results show that AXII and AXIIR play important roles in multiple myeloma (MM) and that targeting the AXII/AXIIR axis may be a novel therapeutic approach for MM.
analysis of the annexin II receptor on human marrow stromal cells
annexin II and its receptor axis play a central role in prostate cancer metastasis, and prostate cancer utilizes the hematopoietic stem cell homing mechanisms to gain access to the niche.
May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.
annexin II receptor
, annexin-2 receptor