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Chymotrypsin-Like Elastase Family, Member 1 Proteins (CELA1)

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Additionally we are shipping Chymotrypsin-Like Elastase Family, Member 1 Antibodies (49) and Chymotrypsin-Like Elastase Family, Member 1 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CELA1 109901 Q91X79
CELA1 1990 Q9UNI1
CELA1 24331 P00773
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Top Chymotrypsin-Like Elastase Family, Member 1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 56 to 66 Days
$2,597.83
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,610.67
Details

CELA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for Chymotrypsin-Like Elastase Family, Member 1 (CELA1) Interaction Partners

Pig (Porcine) Chymotrypsin-Like Elastase Family, Member 1 (CELA1) interaction partners

  1. insights into the PPE and HNE (show ELANE Proteins) inhibition

  2. Here, we studied the priming of SARS (show SARS Proteins)-CoV S by elastase and show an important role for residue Thr (show TRH Proteins)(795) in the S2 domain.

  3. comparison of x-ray structures of alpha1PI complexes with trypsin, PPE, and human neutrophil elastase (show ELANE Proteins)

  4. the oxygen of the oxopropyl group of the inhibitor is present as an oxygen anion rather than a hydroxyl group, supporting the role of the "oxyanion hole" in stabilizing the tetrahedral intermediate in ELS1 catalysis

Mouse (Murine) Chymotrypsin-Like Elastase Family, Member 1 (CELA1) interaction partners

  1. The stretch-dependent expression and binding kinetics of Cela1 indicate an important role in stretch-dependent remodeling of the peripheral lung during development and regeneration.

  2. defines the temporal-spatial pattern of elastin (show ELN Proteins) remodeling during lung development, demonstrates an association of this remodeling with chymotrypsin-like elastase 1

  3. Glucocorticoid receptor (show NR3C1 Proteins)-null lungs included Chi3l3 (show CHI3L3 Proteins) (11-fold, P < 0.05), a macrophage inflammatory response gene and Ela1 (9.4-fold, P < 0.05), an extracellular matrix remodeling enzyme.

Human Chymotrypsin-Like Elastase Family, Member 1 (CELA1) interaction partners

  1. Inverse association of HbA1c with faecal elastase 1 in people without diabetes suggests that pancreatic exocrine dysfunction might be an early disturbance that develops in parallel with hyperglycemia.

  2. The results of the study suggest that the levels of apelin (show APLN Proteins), TNF-alpha (show TNF Proteins) and elastase-1 are important diagnostic markers of CP in patients with type 2 diabetes mellitus.

  3. Results indicate that the extract of the mycelium of Tricholoma matsutake decreased elastase activity in a dose-dependent manner and reduced the levels of matrix metalloproteinase 1 (MMP-1 (show MMP1 Proteins)).

  4. Mutant genes (CELA1, HSPG2, and KCNK5) in Balkan endemic nephropathy patients encode proteins involved in basement membrane/extracellular matrix and vascular tone, tightly connected to process of angiogenesis.

  5. A low value of faecal elastase-1, indicating reduced exocrine pancrease secretion, is strongly correlated with a poor survival in advanced pancreatic cancer.

  6. Hypermethylation of ELA3B (show ELA3B Proteins) gene promoter were associated with pancreatic cancer.

  7. pancreatic elastase induced proinflammatory effects are mediated by TLR4 (show TLR4 Proteins) and NF-kappaB (show NFKB1 Proteins) in human myeloid cells

  8. Parathormone (show PTH Proteins) levels and Vitamin D metabolism in female patients with various grades of fecal ELA1 deficiency are reported.

Chymotrypsin-Like Elastase Family, Member 1 (CELA1) Protein Profile

Protein Summary

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

Gene names and symbols associated with CELA1

  • chymotrypsin-like elastase family, member 1 (cela1)
  • chymotrypsin-like elastase family, member 1 (CELA1)
  • chymotrypsin-like elastase family, member 1 (Cela1)
  • chymotrypsin-like elastase family, member 3B (CELA3B)
  • 1810009A17Rik protein
  • 1810062B19Rik protein
  • CBPP protein
  • E1 protein
  • EL-1 protein
  • Ela-1 protein
  • Ela1 protein
  • ELA3B protein
  • ELAI1 protein
  • Elastase-1 protein
  • ELS1 protein
  • PC-TsF protein
  • RATELAI1 protein

Protein level used designations for CELA1

chymotrypsin-like elastase family, member 1 , pancreatic elastase 1 , chymotrypsin-like elastase family member 1 , pancreatic elastase I , elastase 1, pancreatic , elastase-1 , elastase I , cholesterol-binding pancreatic protease , chymotrypsin-like elastase family member 3B , elastase 1 , elastase 3B, pancreatic , elastase IIIB , elastase-3B , fecal elastase 1 , pancreatic endopeptidase E , protease E , proteinase E

GENE ID SPECIES
398300 Xenopus laevis
396766 Sus scrofa
109901 Mus musculus
1990 Homo sapiens
403515 Canis lupus familiaris
281139 Bos taurus
24331 Rattus norvegicus
494217 Felis catus
23436 Homo sapiens
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