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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Additionally we are shipping Claudin 1 Antibodies (157) and Claudin 1 Proteins (5) and many more products for this protein.
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Cyclosporine A/sirolimus alter claudin-1 expression in renal proximal tubular cells via ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathway to alter barrier function.
Claudin-1 (show CLDN7 ELISA Kits) expression was correlated with lymphatic microvessel generation in hypopharyngeal squamous cell carcinoma and with patient survival.
High CLAUDIN-1 (show CLDN7 ELISA Kits) expression is associated with metastasis in follicular thyroid carcinoma.
The highest expression of claudin-1 (show CLDN7 ELISA Kits) was observed in well-differentiated oral squamous cell carcinomas, whereas poorly differentiated tumors exhibited mostly no expression of claudin-1 (show CLDN7 ELISA Kits).
Report genetic polymorphism of TJ component claudin-1 (show CLDN7 ELISA Kits) and their haplotypes are associated with leukoaraiosis.
Using a human liver-chimeric mouse model, we show that a monoclonal antibody specific for the TJ protein claudin-1 (show CLDN7 ELISA Kits) (ref (show THOC4 ELISA Kits). 7) eliminates chronic HCV infection without detectable toxicity
delocalization of claudin-1 induced by PKC phosphorylation contributes to metastatic capacity of osteosarcoma cells
The expressions of MARVELD2 (show MARVELD2 ELISA Kits), CLDN1 and CLDN3 (show CLDN3 ELISA Kits) mRNA were significantly lower in cholesteatoma tissue and may be involved in epithelium permeability.
There was no difference in the frequency of fractures or renal lithiasis between the rs219780 genotype groups in PHPT patients. Nor was there any relationship between the T or C alleles and BMD (show BEST1 ELISA Kits) or biochemical parameters.
CLD1-mediated hepatoma cell invasiveness occurs via heat shock factor 1 (HSF1) activation.
Findings suggest that CLDN1 is oncogenic in gastric cancer and its malignant potential may be attributed in part to regulation of anoikis, by mediating membrane beta-catenin (show CTNNB1 ELISA Kits)-regulated cell-cell adhesion and cell survival.
Data show that the spatiotemporal expression of claudin-1 is dysregulated in homeobox (show PRRX1 ELISA Kits) (Msx) genes Msx1d/d/Msx2d/d uteri.
Cldn-1 is a positive regulator of osteoblast proliferation and differentiation.
We further demonstrate that KRT76 interacts with CLDN1 and propose that this interaction is necessary to correctly position CLDN1 in tight junctions.
MIR29 targets and reduces expression of CLDN1 and NKRF (show NKRF ELISA Kits) to increase intestinal permeability in inflammatory bowel disease.
Occludin (show OCLN ELISA Kits) and Claudin-1 expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
regulates intestinal epithelial homeostasis via regulation of Notch (show NOTCH1 ELISA Kits)-signalling
Downregulation of Sirt1 (show SIRT1 ELISA Kits) and upregulation of the tight junction protein Claudin-1 by SIRT1 (show SIRT1 ELISA Kits)-mediated epigenetic regulation in podocytes contributed to albuminuria.
Cldn1(-/-) mice exhibited the abnormal stratum granulosum formation and stratum corneum barrier defects.
miR (show MLXIP ELISA Kits)-155 may prevent tumorigenesis in human ovarian cancer through downregulation of CLDN1
Claudin-1 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, dark cell area.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
, claudin 19
, claudin 1
, senescence-associated epithelial membrane protein 1
, tight junction protein