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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Additionally we are shipping Claudin 3 Kits (49) and Claudin 3 Proteins (8) and many more products for this protein.
Showing 10 out of 84 products:
Human Polyclonal CLDN3 Primary Antibody for WB - ABIN2801966
Katahira, Sugiyama, Inoue, Horiguchi, Matsuda, Sugimoto: Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. in The Journal of biological chemistry 1997
Show all 2 references for ABIN2801966
Human Polyclonal CLDN3 Primary Antibody for ELISA, WB - ABIN1532131
Peacock, Keen, Inglehearn: Analysis of a human gene homologous to rat ventral prostate.1 protein. in Genomics 1998
Cln-3 (show CLN3 Antibodies) plays a vital role in TNF (show TNF Antibodies)-modulated paracellular permeability in submandibular epithelium.
Further in vitro studies suggested that the isolated MAbs possessed the desired binding properties for the detection or targeting of CLDN3.
that Claudin-3 expression was restricted to the apical pole of ependymocytes in the subcommissural organ
The expressions of MARVELD2 (show MARVELD2 Antibodies), CLDN1 (show CLDN1 Antibodies) and CLDN3 mRNA were significantly lower in cholesteatoma tissue and may be involved in epithelium permeability.
increased claudin-3 and claudin-4 (show CLDN4 Antibodies) expression may play a postive role in the progression and metastasis of gastric cancer
Univariate analyses indicated that the T stage, lymph node metastasis, the TNM (show ODZ1 Antibodies) stage, and the expression of claudin-3, beta-catenin (show CTNNB1 Antibodies), and vimentin (show VIM Antibodies) were significant predictors for overall survival (OS).
Studies suggest that claudin-3 and claudin-4 (show CLDN4 Antibodies) might be targets for the treatment of chemotherapy-resistant ovarian cancer and other tumors overexpressing claudin-3 and -4 using Clostridium perfringens enterotoxin (CPE (show CPE Antibodies))-based theranostic agents.
Data from live-cell imaging suggest at least two different cis (show CISH Antibodies)-interaction interfaces within CLDN3 homopolymers as well as within CLDN1 (show CLDN1 Antibodies)/CLDN3 heteropolymers.
our findings demonstrated that CLDN3 is an epigenetically silenced metastasis suppressor gene in Hepatocellular carcinoma
Study highlights a profound role for the choroid plexus in the pathogenesis of multiple sclerosis, and implies that CLDN3 may be regarded as a crucial and novel determinant of blood-cerebrospinal fluid barrier integrity
claudin-3 and claudin-5 (show CLDN5 Antibodies) expression is increased by DHEAS (show SULT2A1 Antibodies) and tight junction formation is stimulated via a Gnalpha11-coupled receptor in Sertoli cells
Cldn3(-/-) mice are fertile and show no Sertoli cell tight junction structural defects, even during the stages of Sertoli cell tight junction remodeling when preleptotene spermatocytes translocate from the basal to the adluminal compartment.
Seminiferous stage-specific expression and localization of claudin 3 during spermatogenesis regulate the progression of meiosis by promoting germ cell migration across the blood-testis barrier.
Claudin-3 expression in uterine luminal epithelium is stimulated by progesterone and suppressed by heparin-binding epidermal growth factor-like growth factor (show HBEGF Antibodies).
Claudin-3 and Clara cell 10 kDa protein were identified as possible markers of early tobacco smoke-induced epithelial injury along alveolar ducts.
the results indicate that Grhl2 (show GRHL2 Antibodies) regulates epithelial morphogenesis through transcriptional up-regulation of Cldn3 and Cldn4 (show CLDN4 Antibodies), as well as of Rab25 (show RAB25 Antibodies), which increases the Cldn4 (show CLDN4 Antibodies) protein and its localization at TJs
Claudin-3 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, dark cell area.
Mechanism of Clostridium perfringens enterotoxin interaction with claudin-3/-4 protein suggests structural modifications of the toxin to target specific claudins
Claudin-3 in the apical-most regions maintains the impermeable tight junctions during lactation, and claudin-4 (show CLDN4 Antibodies) contributes to the permeability changes of them immediately after parturition and weaning.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
, CPE-R 2
, CPE-receptor 2
, Clostridium perfringens enterotoxin receptor 2
, ventral prostate.1 protein homolog
, ventral prostate.1-like protein
, clostridium perfringens enterotoxin receptor 2
, ventral prostate.1 protein
, integral membrane protein claudin-3
, tight junction-associated protein