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Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Proteins (CSTF2T)

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Additionally we are shipping Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CSTF2T 83410 Q8C7E9
CSTF2T 23283 Q9H0L4
Rat CSTF2T CSTF2T 309338  
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Top Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CSTF2T Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Interaction Partners

Mouse (Murine) Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) interaction partners

  1. The results suggest that tauCstF-64 plays a role in 3' end determination and transcription termination for a large range of germ cell-expressed genes.

  2. tauCstF-64 is required not only for expression of genes involved in morphological differentiation of spermatids but also for genes having products that function during interaction of motile spermatozoa with eggs.

  3. physiologically increased levels of CstF-64 (show CSTF2 Proteins) observed in LPS (show TLR4 Proteins)-stimulated RAW macrophages contribute to the changes in expression and alternative polyadenylation of a number of genes

  4. These results suggest the hypothesis that tauCstF-64 mRNA is regulated at the translational or post-translational level.

  5. tauCstF-64 promotes germ-cell-specific patterns of polyadenylation by binding to different downstream sequence elements.

  6. Targeted disruption of Cstf2t in mice causes aberrant spermatogenesis, specifically disrupting meiotic and postmeiotic development, resulting in male infertility resembling oligoasthenoteratozoospermia.

  7. The Cstf2t protein contributes to proteomic diversity by regulating alternative polyadenylation of neural mRNAs.

Human Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) interaction partners

  1. Studied expression levels of CstF-64 (show CSTF2 Proteins) in EV71-infected cells; showed reduction of CstF-64 (show CSTF2 Proteins) during virus infection correlated with production of viral 3C(pro). CstF-64 (show CSTF2 Proteins) was cleaved in vitro by 3C(pro) not by mutant 3C(pro) variants.

  2. Radiation hybrid mapping places the human tauCstF-64 gene at 10q22-q23, which is the site of a translocation that has been associated with human neurological problems and male infertility.

  3. structure of the RNA-binding domain of CstF-64 (show CSTF2 Proteins) containing an RNA recognition motif (RRM) augmented by N- and C-terminal helices

  4. upstream element in human papillomavirus type 16 interacted specifically with CstF-64 (show CSTF2 Proteins), hnRNP C1/C2 (show HNRNPC Proteins) & polypyrimidine tract binding protein (show PTBP1 Proteins), suggesting these factors were enhancing or regulating polyadenylation at the HPV-16 early polyadenylation signal

Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Protein Profile

Protein Summary

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs.

Gene names and symbols associated with CSTF2T

  • cleavage stimulation factor, 3' pre-RNA subunit 2, tau (Cstf2t)
  • cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant (CSTF2T)
  • cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant (Cstf2t)
  • 64kDa protein
  • C77975 protein
  • CstF-64T protein
  • tauCstF-64 protein
  • tCstF-64 protein

Protein level used designations for CSTF2T

CF-1 64 kDa subunit tau , CF-1 64 kDa subunit, tau , CSTF 64 kDa subunit tau , CSTF 64 kDa subunit, tau , cleavage stimulation factor 64 kDa subunit tau , cleavage stimulation factor 64 kDa subunit, tau , cleavage stimulation factor subunit 2 tau , cleavage stimulation factor subunit 2 tau variant , cleavage stimulation factor, 3' pre-RNA subunit 2, 64 kDa, tau , tauCstF-64 , cleavage stimulation factor, 3' pre-RNA subunit 2, tau

GENE ID SPECIES
83410 Mus musculus
23283 Homo sapiens
783569 Bos taurus
309338 Rattus norvegicus
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