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Cleavage and Polyadenylation Specific Factor 3, 73kDa Proteins (CPSF3)

CPSF3 encodes a member of the metallo-beta-lactamase family. Additionally we are shipping CPSF3 Antibodies (57) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CPSF3 51692 Q9UKF6
Rat CPSF3 CPSF3 298916  
CPSF3 54451 Q9QXK7
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Top CPSF3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CPSF3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) Interaction Partners

Human Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) interaction partners

  1. the molecular mechanism that recruits the CPSF73 endonuclease to histone pre-mRNAs

  2. The data support a model where Star-PAP (show TUT1 Proteins) binds to the pre-mRNA, recruits the CPSF complex to the 3'-end of pre-mRNA and then defines cleavage by CPSF 73 and subsequent polyadenylation of its target mRNAs.

  3. up-regulated by HIV-1 TAT (show TAT Proteins) protein; this could represent a novel mechanism by which HIV increases mRNA processing, causing an increase in both cell and viral gene expression.

  4. crystal structures of human CPSF-73 at 2.1 A resolution, complexed with zinc ions and a sulphate that might mimic the phosphate group of the substrate; CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

  5. this study identifies CPSF-73 as an important regulatory protein that represses the basal transcriptional activity of the HIV-1 LTR promoter

  6. Conserved residues in CPSF-73 and CPSF2 (show CPSF2 Proteins) are required for assembly of the endonuclease activity that cleaves histone pre-mRNAs.

  7. CSR1 (show SCARA3 Proteins) appears to induce cell death through a novel mechanism by hijacking a critical RNA processing enzyme CPSF3.

  8. Degradation of the downstream cleavage product (DCP (show ACE Proteins)) does not depend on the Xrn2 (show XRN2 Proteins) 5' exonuclease (show EXO1 Proteins), suggesting that CPSF-73 degrades the DCP (show ACE Proteins) both in vitro and in vivo.

  9. The tumor suppressor Cdc73 (show CDC73 Proteins) functionally associates with CPSF and CstF 3 (show CSTF3 Proteins)' mRNA processing factors.

CPSF3 Protein Profile

Protein Summary

This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing.

Gene names and symbols associated with CPSF3

  • cleavage and polyadenylation specific factor 3, 73kDa (CPSF3)
  • cleavage and polyadenylation specific factor 3, 73kDa (cpsf3)
  • cleavage and polyadenylation specificity factor subunit 3 (CpipJ_CPIJ011955)
  • cleavage and polyadenylation specificity factor subunit 3 (CMU_024380)
  • cleavage and polyadenylation specificity factor subunit 3 (PITG_07110)
  • cleavage and polyadenylation specific factor 3 (cpsf3)
  • cleavage and polyadenylation specific factor 3, 73kDa (LOC100354833)
  • cleavage and polyadenylation specific factor 3, 73kDa (Cpsf3)
  • cleavage and polyadenylation specificity factor 3 (Cpsf3)
  • CPSF-73 protein
  • CPSF3 protein
  • CPSF73 protein
  • si:dkey-81b15.1 protein
  • wu:fc32f10 protein
  • zgc:101655 protein

Protein level used designations for CPSF3

cleavage and polyadenylation specificity factor 73 kDa subunit , cleavage and polyadenylation specificity factor subunit 3 , cleavage and polyadenylation specificity factor 3 , cleavage and polyadenylation specific factor 3, 73kDa , cleavage and polyadenylation specificity factor subunit 3-like , mRNA 3'-end-processing endonuclease CPSF-73 , CPSF 73 kDa subunit

GENE ID SPECIES
459017 Pan troglodytes
448456 Xenopus (Silurana) tropicalis
694036 Macaca mulatta
421929 Gallus gallus
100174072 Pongo abelii
6044555 Culex quinquefasciatus
6995165 Cryptosporidium muris RN66
9464071 Phytophthora infestans T30-4
100194853 Salmo salar
100354833 Oryctolagus cuniculus
100407252 Callithrix jacchus
100564303 Anolis carolinensis
100604815 Nomascus leucogenys
324554 Danio rerio
495111 Xenopus laevis
51692 Homo sapiens
482962 Canis lupus familiaris
281712 Bos taurus
298916 Rattus norvegicus
54451 Mus musculus
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