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CCDC88B encodes a member of the hook-related protein family. Additionally we are shipping CCDC88B Kits (12) and CCDC88B Proteins (3) and many more products for this protein.
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results demonstrate an important role for HkRP3 in regulating the clustering of lytic granules and MTOC repositioning during the development of NK cell-mediated killing.
A genotype dataset found a sarcoidosis risk locus on chromosome 11q13.1, a risk region for Crohn disease. An allele-dependent expression of CCDC88B was found in bronchoalveolar lavage samples of German, Swedish and Czech patients with sarcoidosis.
Data show that a novel Girdin (show CCDC88A Antibodies) family protein, Gipie, is expressed in endothelial cells, where it interacts with GRP78 (show HSPA5 Antibodies), a master regulator of the UPR, and that Gipie/GRP78 (show HSPA5 Antibodies) interaction controls the IRE1 (show ERN1 Antibodies)-JNK (show MAPK8 Antibodies) signaling pathway.
These results identify CCDC88B as a novel and important regulator of T cell function.
This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules.
78 kDa glucose-regulated protein [GRP78]-interacting protein induced by ER stress
, GRP78-interacting protein induced by ER stress
, brain leucine zipper domain-containing protein
, brain leucine zipper protein
, coiled-coil domain-containing protein 88B
, hook-related protein 3
, coiled-coil domain containing 88