You are viewing an incomplete version of our website. Please click to reload the website as full version.

Collagen, Type VI, alpha 2 Proteins (COL6A2)

COL6A2 encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. Additionally we are shipping Collagen, Type VI, alpha 2 Antibodies (41) and Collagen, Type VI, alpha 2 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
COL6A2 1292 P12110
COL6A2 12834 Q02788
Rat COL6A2 COL6A2 361821  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Collagen, Type VI, alpha 2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

COL6A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Collagen, Type VI, alpha 2 (COL6A2) Interaction Partners

Human Collagen, Type VI, alpha 2 (COL6A2) interaction partners

  1. Parental mosaicism was confirmed in the four families through quantitative analysis of the ratio of mutant versus wild-type allele (COL6A1 (show COL6A1 Proteins), COL6A2, and COL6A3 (show COL6a3 Proteins)) in genomic DNA from various tissues; consistent with somatic mosaicism, parental samples had lower ratios of mutant versus wild-type allele compared with the fully heterozygote offspring.

  2. Mutations in COL6A2 gene are associated with aberrant mitochondria in Bethlem myopathy.

  3. In UCMD, 8 mutations were identified in COL6A2 in Chinese patients.

  4. Mutations in each of the three collagen VI genes, COL6A1 (show COL6A1 Proteins), COL6A2 and COL6A3 (show COL6a3 Proteins), cause four types of muscle disorders: Ullrich congenital muscular dystrophy, Bethlem myopathy, limb-girdle muscular dystrophy, and autosomal recessive myosclerosis. (Review)

  5. COL6A2 is overexpressed in Down syndrome-affected umbilical cords at early and term gestational ages.

  6. Homozygous COL6A2 mutation, p.Asp215Asn, was identified in both affected siblings. We conclude that the COL6A2 p.Asp215Asn mutation is likely to be responsible for PME (show CSTB Proteins) (Progressive Myoclonus Epilepsy) in this family.

  7. A deletion within intron 1A of the COL6A2 gene, occurring in compound heterozygosity with a small deletion in exon 28, was identified in a BM patient.

  8. the C2A splice variant has a role in recessive COL6A2 C-globular missense mutations in Ullrich congenital muscular dystrophy

  9. The alpha2(VI) chain modulates matrix-metalloproteinase (show MMP20 Proteins) (MMP) availability by sequestering proMMPs in the extracellular matrix, blocking proteolytic activity.

  10. Haplotype analysis clearly suggested linkage of Ullrich muscular dystrophy to the COL6A1 (show COL6A1 Proteins)/2 locus in two cases and to the COL6A3 (show COL6a3 Proteins) loci in the third case. In the remaining nine patients, primary collagen VI involvement was excluded

Collagen, Type VI, alpha 2 (COL6A2) Protein Profile

Protein Summary

This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.

Gene names and symbols associated with COL6A2

  • collagen, type VI, alpha 2 (COL6A2)
  • collagen, type VI, alpha 2 (col6a2)
  • collagen, type VI, alpha 2 (LOC100224039)
  • collagen, type VI, alpha 2 (Tcur_3411)
  • collagen, type VI, alpha 2 (Col6a2)
  • Col6a-2 protein
  • PP3610 protein

Protein level used designations for COL6A2

collagen alpha-2(VI) chain , alpha 2 type VI collagen , collagen, type VI, alpha 2 , collagen VI, alpha-2 polypeptide , human mRNA for collagen VI alpha-2 C-terminal globular domain , collagen type VI alpha 2 , procollagen, type VI, alpha 2 , type VI collagen alpha-2 subunit

GENE ID SPECIES
282194 Bos taurus
474056 Pan troglodytes
567771 Danio rerio
709493 Macaca mulatta
100224039 Taeniopygia guttata
8604757 Thermomonospora curvata DSM 43183
100055332 Equus caballus
100602701 Nomascus leucogenys
1292 Homo sapiens
100101552 Sus scrofa
12834 Mus musculus
361821 Rattus norvegicus
396292 Gallus gallus
Selected quality suppliers for Collagen, Type VI, alpha 2 Proteins (COL6A2)
Did you look for something else?