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The protein encoded by CSF3 is a cytokine that controls the production, differentiation, and function of granulocytes. Additionally we are shipping Colony Stimulating Factor 3 (Granulocyte) Antibodies (293) and Colony Stimulating Factor 3 (Granulocyte) Proteins (122) and many more products for this protein.
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Human CSF3 ELISA Kit for Sandwich ELISA - ABIN411275
Kanda, Fukushige, Murotsu, Yoshida, Tsuchiya, Asano, Kaziro, Nagata: Human gene coding for granulocyte-colony stimulating factor is assigned to the q21-q22 region of chromosome 17. in Somatic cell and molecular genetics 1987
data provide novel information about the regulation of neutrophil migration in zebrafish, positioning Gcsf-Chr19 as a key signal during the course of an inflammatory process triggered by severe damage
Data indicate that Gcsf is required for the specification and proliferation of hematopoietic stem cells, suggesting that Gcsf represents an ancestral cytokine responsible for the broad support of hematopoietic stem and progenitor cells (HSPCs).
findings provide convincing evidence that monophosphoryl lipid A-induced G-CSF facilitates early expansion, mobilization, and recruitment of neutrophils to the site of infection after burn injury
Overexpression of VEGF (show VEGFA ELISA Kits) may compensate for the G-CSF deficit through preservation of cellular components, including blood vessels, in the postinfarction heart.
G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy.
constitutive activation of the NF-kappaB (show NFKB1 ELISA Kits) pathway in CAIX (show CA9 ELISA Kits)-depleted cells restored G-CSF secretion
Exposure of Sca-1(+) cells to G-CSF in the culture medium for 72 h induced time-dependent but self-limiting cell cycle acceleration with a restricted effect on the CSC proliferation.
these results suggest that the G-CSF pathway regulates the production of autoantibodies in murine models of lupus.
G-CSF acts in a cell intrinsic manner to expand multipotent progenitors to increase production of tumor-derived Ly6G+ neutrophils.
Endothelial cell(EC)-intrinsic MYD88 (show MYD88 ELISA Kits) signaling and subsequent G-CSF production by ECs is required for myeloid progenitor lineage skewing toward granulocyte-macrophage progenitors, increased colony-forming unit granulocyte activity.
Adventitial CXCL1 (show CXCL1 ELISA Kits)/granulocyte-colony stimulating factor expression in response to aortic dissection triggers local neutrophil recruitment and activation. This leads to adventitial inflammation via IL-6 (show IL6 ELISA Kits) and results in aortic expansion and rupture.
Cultured mouse enteric nervous system -neurospheres show increased expansion with increased G-CSF concentrations, in contrast to central nervous system - derived spheres.
G-CSF stimulates beta1 integrin expression and Swan (show RBM12 ELISA Kits) 71 cell migration by activating PI3K (show PIK3CA ELISA Kits) and MAPK (show MAPK1 ELISA Kits) signaling pathways.
these data suggest that G-CSF may contribute to tumor growth and decrease the antitumor effect of radiotherapy, possibly by promoting vascularization in cancer lesions.
in vitro chemotaxis assays and an in vivo transplantation model for chemoattraction confirmed that UCX((R)) are chemotactic to CD34 (show CD34 ELISA Kits)(-)/CD45 (show PTPRC ELISA Kits)(-) BM-MSCs via a cell-specific mobilization mechanism mediated by G-CSF.
Case Report: undifferentiated colon carcinoma producing G-CSF.
increases MMP-2 (show MMP2 ELISA Kits) activity and VEGF (show VEGFA ELISA Kits) secretion in trophoblasts through activation of PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) and Erk (show EPHB2 ELISA Kits) signaling pathways
Elevated IL-8 (show IL8 ELISA Kits) and G-CSF may be involved in the pathophysiology of narcolepsy.
G-CSF- or GM-CSF (show CSF2 ELISA Kits)-secreting cancers, albeit not very common are, however, among the most rapidly advancing ones due to a cytokine-mediated immune suppression and angiogenesis. [Review]
GM-CSF (show CSF2 ELISA Kits), through its stimulatory function on macrophages, may promote aneurysm progression.
G-CSF constrains cancer to grow and progress by, respectively, supporting the survival of sympathetic nerve fibers in 6-hydroxydopamine-sympathectomized mice.
Transgenic poultry with a gene of human granulocyte colony-stimulating factor (gcsf) was developed by arti- ficial insemination with the transfected sperm
Data suggest granulocyte-colony stimulating factor (G-CSF) as a possible candidate for agents in which neutrophils can provide protection.
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene.
colony stimulating factor 3 (granulocyte)
, granulocyte colony-stimulating factor
, granulocyte colony stimulating factor
, Granulocyte colony-stimulating factor