anti-Complement Component 5a Receptor 1 (C5AR1) Antibodies

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Additionally we are shipping C5AR1 Kits (13) and C5AR1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C5AR1 728 P21730
C5AR1 12273  
C5AR1 113959 P97520
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Top anti-C5AR1 Antibodies at antibodies-online.com

Showing 10 out of 295 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using CD88/C5aR (Phospho-Ser338) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p), WB Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD88 (ABIN181855). 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD88 expression in A549 (A), mouse brain (B), rat spleen (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Cow Mouse Un-conjugated FACS, IHC (p), WB Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD88 (ABIN118843). 0.2 mg Log in to see 6 to 8 Days
$588.50
Details
Human Rat Biotin FACS 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated FACS, WB C5AR1 Antibody (Center) (ABIN654658) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the C5AR1 antibody detected the C5AR1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB C5AR1 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. C5AR1 Antibody (Center) western blot analysis in A549 cell line lysates (35µg/lane).This demonstrates the C5AR1 antibody detected the C5AR1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Rat Mouse PE FACS Staining of rat peripheral blood granulocytes probed with MOUSE ANTI RAT CD88 : RPE 100 Tests Log in to see 6 to 8 Days
$511.50
Details
Human Mouse Fluorescein FACS Detection of Complement Component C5a R1 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Complement Component C5a R1 Fluorescein-conjugated Monoclonal Antibody. Detection of Complement Component C5a R1 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Complement Component C5a R1 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$267.75
Details

C5AR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-C5AR1 Antibodies

  1. Human Monoclonal C5AR1 Primary Antibody for IHC (f), IHC (fro) - ABIN2689428 : Fayyazi, Sandau, Duong, Götze, Radzun, Schweyer, Soruri, Zwirner: C5a receptor and interleukin-6 are expressed in tissue macrophages and stimulated keratinocytes but not in pulmonary and intestinal epithelial cells. in The American journal of pathology 1999 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN2689430 : Floreani, Heires, Welniak, Miller-Lindholm, Clark-Pierce, Rennard, Morgan, Sanderson: Expression of receptors for C5a anaphylatoxin (CD88) on human bronchial epithelial cells: enhancement of C5a-mediated release of IL-8 upon exposure to cigarette smoke. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal C5AR1 Primary Antibody for FACS, IP - ABIN1981892 : Camous, Roumenina, Bigot, Brachemi, Frémeaux-Bacchi, Lesavre, Halbwachs-Mecarelli: Complement alternative pathway acts as a positive feedback amplification of neutrophil activation. in Blood 2011 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal C5AR1 Primary Antibody for FACS, IHC (p) - ABIN1774738 : Cain, Monk: The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74). in The Journal of biological chemistry 2002 (PubMed)
    Show all 3 Pubmed References

  5. Mouse (Murine) Monoclonal C5AR1 Primary Antibody for Func, FACS - ABIN2472749 : Vaccaro, De Giorgi, Gallo, Vaccaro, Compare: [Various unusual morpho-pathologic cases of extrapulmonary tuberculosis]. in Archivio Monaldi per le malattie del torace 1993 (PubMed)
    Show all 4 Pubmed References

  6. Mouse (Murine) Monoclonal C5AR1 Primary Antibody for FACS - ABIN2472751 : Soruri, Kim, Kiafard, Zwirner: Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody. in Immunology letters 2003 (PubMed)
    Show all 4 Pubmed References

  7. Mouse (Murine) Monoclonal C5AR1 Primary Antibody for IHC (fro), FACS - ABIN2472739 : Zola, Melo, Zowtyj, Nikoloutsopoulos, Skinner: The leukocyte-common antigen (CD45) complex and B-lymphocyte activation. in Human immunology 1990 (PubMed)
    Show all 4 Pubmed References

  8. Mouse (Murine) Monoclonal C5AR1 Primary Antibody for FACS - ABIN2472745 : Shagdarsuren, Bidzhekov, Mause, Simsekyilmaz, Polakowski, Hawlisch, Gessner, Zernecke, Weber: C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice. in Circulation 2010 (PubMed)
    Show all 4 Pubmed References

  9. Mouse (Murine) Monoclonal C5AR1 Primary Antibody for FACS - ABIN2472747 : Godau, Heller, Hawlisch, Trappe, Howells, Best, Zwirner, Verbeek, Hogarth, Gerard, Van Rooijen, Klos, Gessner, Köhl: C5a initiates the inflammatory cascade in immune complex peritonitis. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 4 Pubmed References

  10. Mouse (Murine) Monoclonal C5AR1 Primary Antibody for FACS - ABIN2472748 : Manthey, Thomas, Shiels, Zernecke, Woodruff, Rolfe, Taylor: Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 (PubMed)
    Show all 4 Pubmed References

More Antibodies against C5AR1 Interaction Partners

Human Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. C5a/C5aR pathway promotes gastric cancer pathogenesis by suppressing p21 (show CDKN1A Antibodies)/p-p21 (show CDKN1A Antibodies) expression via activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling.

  2. C5aR plays a role in T helper cell polarization induced by Mycobacterium tuberculosis and this effect is strain- and donor-dependent.

  3. Panton-Valentine leucotoxin LukS-PV/LukF-PV and the gamma-hemolysin (show PLC Antibodies) HlgC/HlgB, bind the C5a complement-derived peptide receptor, inducing intracellular calcium release in neutrophils.

  4. Studies indicate that the complement response lie the active fragments, C3a (show C3 Antibodies) and C5a, acting through their specific receptors, C3aR (show C3AR1 Antibodies), C5aR1 and C5aR2 to direct the cellular response to inflammation.

  5. TLR4 (show TLR4 Antibodies) and C5aR crosstalk in dendritic cells induces a core regulatory network of RSK2 (show RPS6KA3 Antibodies), PI3Kbeta, SGK1 (show SGK1 Antibodies), and FOXO (show FOXO3 Antibodies) transcription factors.

  6. Results showed that 7-oxygenated cholesterol derivatives have differential effects on monocyte/macrophage expression of IL-8 (show IL8 Antibodies) and C5a receptor and that C5a receptor is involved in 7alphaOHChol-induced IL-8 (show IL8 Antibodies) expression via PI3K (show PIK3CA Antibodies) and MEK (show MAP2K1 Antibodies). Study demonstrated expression of IL-8 (show IL8 Antibodies) and C5a receptor primarily by 7alpha-hydroxycholesterol in monocytes/macrophages.

  7. Reducing RPS19 (show RPS19 Antibodies) in tumor cells or blocking the C5a receptor 1-RPS19 (show RPS19 Antibodies) interaction decreases RPS19 (show RPS19 Antibodies)-mediated immunosuppression, impairs tumor growth, and delays the development of tumors in a transgenic model of breast cancer

  8. C5aR expression in gastric cancer was associated with cancer progression, liver metastasis, and poor prognosis.

  9. this study shows that downregulation of CD88 after stimulation with IL-8 (show IL8 Antibodies) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 Antibodies) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults

  10. Relation of C5aR expression to tumor development and poor prognosis of the breast cancer patients

Mouse (Murine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. C5aR1 facilities the pathogenesis of chronic kidney infection by enhancement of bacterial colonization of tubular epithelium, promotion of local inflammatory responses, and impairment of phagocytic function of monocytes/macrophages.

  2. Data indicate that complement component 5a receptor 1 protein (C5aR1) signaling in osteoblasts plays a detrimental role in bone regeneration after fracture.

  3. The role of C5aR1 and C5aR2 in response to renal ischemia-reperfusion injury is reported. The results also demonstrated that C5aR2 is a functional receptor, rather than a decoy receptor, and may provide a new target for intervention.

  4. these data reveal a differential role for C5aR during ethanol-induced liver inflammation and injury

  5. These findings demonstrate a complex regulation pattern of C5aR1 in the airways, lung tissue and mediastinal lymph nodes of mice, suggesting that the C5a/C5aR1 axis controls airway constriction and inflammation through activation of myeloid cells in all three compartments in an experimental model of allergic asthma.

  6. C5aR1-KO mice exhibited less renal injury, as evidenced by reduced albuminuria. In contrast, cardiac injury was accelerated with increased cardiac fibrosis and heart weight in C5aR1-deficient mice after ANG II (show AGT Antibodies) infusion. No effect was found on blood pressure. the C5a:C5aR1 axis drives end-organ damage in the kidney but protects from the development of cardiac fibrosis and hypertrophy in experimental hypertension.

  7. This study demonstrated that C5aR1 contributes to the acute inflammatory response elicited by infiltrating immune cells following pilocarpine status epilepticus.

  8. Regulation of complement 5a receptor (C5aR)-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 Antibodies)) depends on galectin-3 (show LGALS3 Antibodies).

  9. The C5a/C5aR pathway is essential for up-regulating SphK1 (show SPHK1 Antibodies) expression through p38 MAPK (show MAPK14 Antibodies) activation in acute liver failure.in mice.

  10. C5a bidirectionally amplifies TLR4 (show TLR4 Antibodies)-mediated NLRP3 (show NLRP3 Antibodies) inflammasome activation in monocytes while suppressing this pathway in macrophages. However, as C5aR1 deficiency attenuates the IL-1beta (show IL1B Antibodies) response to LPS (show TLR4 Antibodies) challenge in vivo, results suggest overall that C5a augments physiologic inflammasome responses.

Cow (Bovine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. Studies provide information regarding distinct structural and functional features that may contribute to the unique pharmacological properties of bovine C5aR.

C5AR1 Antigen Profile

Protein Summary

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene names and symbols associated with C5AR1

  • complement C5a receptor 1 (C5AR1) antibody
  • complement component 5a receptor 1 (C5ar1) antibody
  • complement C5a receptor 1 (C5ar1) antibody
  • complement component 5a receptor 1 (c5ar1) antibody
  • C5A antibody
  • C5aR antibody
  • C5r1 antibody
  • Cd88 antibody
  • D7Msu1 antibody
  • GPR77 antibody

Protein level used designations for C5AR1

C5a anaphylatoxin chemotactic receptor 1 , C5a anaphylatoxin receptor , C5a ligand , C5a-R , complement component 5 receptor 1 , complement component 5, receptor 1 , C5aR , complement C5a receptor , G protein-coupled receptor 77 , complement component 5 receptor 1 (C5a ligand) , C5a anaphylatoxin chemotactic receptor , anaphylatoxin C5a receptor , complement component 5a receptor 1

GENE ID SPECIES
728 Homo sapiens
12273 Mus musculus
113959 Rattus norvegicus
430484 Gallus gallus
442974 Canis lupus familiaris
468931 Pan troglodytes
493645 Bos taurus
718056 Macaca mulatta
100048955 Sus scrofa
100135489 Cavia porcellus
100379958 Xenopus (Silurana) tropicalis
100589337 Nomascus leucogenys
100352978 Oryctolagus cuniculus
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