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anti-Complement Component 5a Receptor 1 (C5AR1) Antibodies

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Additionally we are shipping C5AR1 Kits (12) and C5AR1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C5AR1 12273  
C5AR1 728 P21730
C5AR1 113959 P97520
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Top anti-C5AR1 Antibodies at antibodies-online.com

Showing 10 out of 261 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Mouse Un-conjugated FACS, IHC (p), WB Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD88 (ABIN118843). 0.2 mg Log in to see 6 to 8 Days
$588.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p), WB Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD88 (ABIN181855). 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rat Biotin FACS 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated FACS, WB C5AR1 Antibody (Center) (ABIN654658) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the C5AR1 antibody detected the C5AR1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Rat Mouse PE FACS Staining of rat peripheral blood granulocytes probed with MOUSE ANTI RAT CD88 : RPE 100 Tests Log in to see 6 to 8 Days
$511.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using CD88/C5aR (Phospho-Ser338) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB C5AR1 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. C5AR1 Antibody (Center) western blot analysis in A549 cell line lysates (35µg/lane).This demonstrates the C5AR1 antibody detected the C5AR1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Fluorescein FACS Detection of Complement Component C5a R1 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Complement Component C5a R1 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$267.75
Details
Human Mouse PE FACS Detection of Complement Component C5a R1 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Complement Component C5a R1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$320.25
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details

C5AR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-C5AR1 Antibodies

  1. Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN951419 : Kiafard, Tschernig, Schweyer, Bley, Neumann, Zwirner: Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in tubular epithelial cells of human, murine and rat kidneys. in Immunobiology 2007 (PubMed)
    Show all 6 references for ABIN951419

  2. Human Polyclonal C5AR1 Primary Antibody for EIA, FACS - ABIN951423 : Skeie, Fingert, Russell, Stone, Mullins: Complement component C5a activates ICAM-1 expression on human choroidal endothelial cells. in Investigative ophthalmology & visual science 2010 (PubMed)
    Show all 5 references for ABIN951423

  3. Human Monoclonal C5AR1 Primary Antibody for FACS, IHC (fro) - ABIN181855 : Oppermann, Raedt, Hebell, Schmidt, Zimmermann, Götze: Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)
    Show all 3 references for ABIN181855

  4. Human Polyclonal C5AR1 Primary Antibody for IHC, ELISA - ABIN1531549 : Gerard, Gerard: The chemotactic receptor for human C5a anaphylatoxin. in Nature 1991 (PubMed)
    Show all 3 references for ABIN1531549

  5. Rat (Rattus) Monoclonal C5AR1 Primary Antibody for FACS - ABIN120012 : Rothermel, Götze, Zahn, Schlaf: Analysis of the tissue distribution of the rat C5a receptor and inhibition of C5a-mediated effects through the use of two MoAbs. in Scandinavian journal of immunology 2000 (PubMed)
    Show all 2 references for ABIN120012

  6. Cow (Bovine) Monoclonal C5AR1 Primary Antibody for FACS, IHC (p) - ABIN118843 : Werfel, Zwirner, Oppermann, Sieber, Begemann, Drommer, Kapp, Götze: CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin. in Journal of immunology (Baltimore, Md. : 1950) 1996 (PubMed)
    Show all 2 references for ABIN118843

  7. Human Polyclonal C5AR1 Primary Antibody for FACS, WB - ABIN654658 : Marc, Kristan, Rozman, Kern, Flezar, Kosnik, Korosec: Complement factor C5a in acute exacerbation of Chronic Obstructive Pulmonary Disease. in Scandinavian journal of immunology 2010 (PubMed)
    Show all 2 references for ABIN654658

  8. Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN4895404 : Pundir, MacDonald, Kulka: The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  9. Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN4895403 : Reis, Chen, Sfyroera, Monk, Köhl, Ricklin, Lambris: C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

More Antibodies against C5AR1 Interaction Partners

Mouse (Murine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. C5aR1-KO mice exhibited less renal injury, as evidenced by reduced albuminuria. In contrast, cardiac injury was accelerated with increased cardiac fibrosis and heart weight in C5aR1-deficient mice after ANG II (show AGT Antibodies) infusion. No effect was found on blood pressure. the C5a:C5aR1 axis drives end-organ damage in the kidney but protects from the development of cardiac fibrosis and hypertrophy in experimental hypertension.

  2. This study demonstrated that C5aR1 contributes to the acute inflammatory response elicited by infiltrating immune cells following pilocarpine status epilepticus.

  3. Regulation of complement 5a receptor (C5aR)-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 Antibodies)) depends on galectin-3 (show LGALS3 Antibodies).

  4. The C5a/C5aR pathway is essential for up-regulating SphK1 (show SPHK1 Antibodies) expression through p38 MAPK (show MAPK14 Antibodies) activation in acute liver failure.in mice.

  5. C5a bidirectionally amplifies TLR4 (show TLR4 Antibodies)-mediated NLRP3 (show NLRP3 Antibodies) inflammasome activation in monocytes while suppressing this pathway in macrophages. However, as C5aR1 deficiency attenuates the IL-1beta (show IL1B Antibodies) response to LPS (show TLR4 Antibodies) challenge in vivo, results suggest overall that C5a augments physiologic inflammasome responses.

  6. CYP4F18 (show CYP4F3 Antibodies)-deficient neutrophils exhibit increased chemotaxis to complement component C5a.

  7. showed that C3a (show C3 Antibodies) receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods

  8. Knockout of the C5aR1 attenuated the effect of beta1-AR in the heart, suggesting an association between the beta1-AR and C5aR1, although further investigation is required to determine if this is a direct or causal association

  9. Data (including data from studies in knockout mice) suggest that C5aR/C5aR (complement C5a/anaphylatoxin (show C5 Antibodies) C5a Receptor) signaling pathway is involved in neurocognitive injury in uninfected pups induced by malaria in pregnancy.

  10. Data indicate that C5ar1 activation plays a role in seizure initiation and severity, as well as neuronal degeneration following status epilepticus.

Human Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. C5aR expression in gastric cancer was associated with cancer progression, liver metastasis, and poor prognosis.

  2. this study shows that downregulation of CD88 after stimulation with IL-8 (show IL8 Antibodies) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 Antibodies) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults

  3. Relation of C5aR expression to tumor development and poor prognosis of the breast cancer patients

  4. The objective of the present study was to validate a receptor occupancy (RO) assay for a human anti-C5aR monoclonal antibody drug candidate, NNC0215-0384 (NN0384)

  5. These data thus suggest that C5aR1 acts as an enhancer of CCR5 (show CCR5 Antibodies)-mediated HIV entry into macrophages, the targeting of which may prove useful to reduce HIV infection by R5 strains.

  6. C5AR and C5L2 (show GPR77 Antibodies)-mediated neutrophil dysfunction is associated with a poor outcome in sepsis.

  7. that C5aR stimulates cell invasion and migration via ERK1/2 (show MAPK1/3 Antibodies)-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells

  8. Inhibition of C5aR1 leads to a significant reduction of CD66b and CD11b (show ITGAM Antibodies) expression indicating a lower neutrophil activation status and block of granule exocytosis.

  9. that rs10853784 of C5aR1 gene are associated with coronary artery disease in Han population of China

  10. 96.7% of the metastatic RCCs had C5aR expression, vs. 50.5% of the non-metastatic ones. C5a triggered ERK (show EPHB2 Antibodies)- and PI3Kdependent invasion of the C5aR-expressing renal carcinoma (show TSC2 Antibodies) cells. The C5a-C5aR axis plays a crucial role in renal carcinoma (show TSC2 Antibodies) cell invasion.

Cow (Bovine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. Studies provide information regarding distinct structural and functional features that may contribute to the unique pharmacological properties of bovine C5aR.

C5AR1 Antigen Profile

Protein Summary

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene names and symbols associated with C5AR1

  • complement component 5a receptor 1 (C5AR1) antibody
  • complement component 5a receptor 1 (c5ar1) antibody
  • C5a anaphylatoxin chemotactic receptor-like (LOC100352978) antibody
  • complement component 5a receptor 1 (C5ar1) antibody
  • C5A antibody
  • C5AR antibody
  • C5AR1 antibody
  • C5r1 antibody
  • CD88 antibody
  • D7Msu1 antibody
  • GPR77 antibody

Protein level used designations for C5AR1

complement component 5a receptor 1 , C5a anaphylatoxin receptor , G protein-coupled receptor 77 , C5a anaphylatoxin chemotactic receptor 1 , C5a ligand , C5a-R , complement component 5, receptor 1 , complement component 5 receptor 1 , C5aR , complement C5a receptor , anaphylatoxin C5a receptor , complement component 5 receptor 1 (C5a ligand) , C5a anaphylatoxin chemotactic receptor

GENE ID SPECIES
397287 Sus scrofa
430484 Gallus gallus
100379958 Xenopus (Silurana) tropicalis
100589337 Nomascus leucogenys
100352978 Oryctolagus cuniculus
12273 Mus musculus
728 Homo sapiens
113959 Rattus norvegicus
100135489 Cavia porcellus
442974 Canis lupus familiaris
718056 Macaca mulatta
468931 Pan troglodytes
100048955 Sus scrofa
493645 Bos taurus
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