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Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Additionally we are shipping C5AR1 Kits (12) and C5AR1 Proteins (7) and many more products for this protein.
Showing 10 out of 261 products:
Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN951419
Kiafard, Tschernig, Schweyer, Bley, Neumann, Zwirner: Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in tubular epithelial cells of human, murine and rat kidneys. in Immunobiology 2007
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Human Polyclonal C5AR1 Primary Antibody for EIA, FACS - ABIN951423
Skeie, Fingert, Russell, Stone, Mullins: Complement component C5a activates ICAM-1 expression on human choroidal endothelial cells. in Investigative ophthalmology & visual science 2010
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Human Monoclonal C5AR1 Primary Antibody for FACS, IHC (fro) - ABIN181855
Oppermann, Raedt, Hebell, Schmidt, Zimmermann, Götze: Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. in Journal of immunology (Baltimore, Md. : 1950) 1993
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Human Polyclonal C5AR1 Primary Antibody for IHC, ELISA - ABIN1531549
Gerard, Gerard: The chemotactic receptor for human C5a anaphylatoxin. in Nature 1991
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Rat (Rattus) Monoclonal C5AR1 Primary Antibody for FACS - ABIN120012
Rothermel, Götze, Zahn, Schlaf: Analysis of the tissue distribution of the rat C5a receptor and inhibition of C5a-mediated effects through the use of two MoAbs. in Scandinavian journal of immunology 2000
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Cow (Bovine) Monoclonal C5AR1 Primary Antibody for FACS, IHC (p) - ABIN118843
Werfel, Zwirner, Oppermann, Sieber, Begemann, Drommer, Kapp, Götze: CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin. in Journal of immunology (Baltimore, Md. : 1950) 1996
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Human Polyclonal C5AR1 Primary Antibody for FACS, WB - ABIN654658
Marc, Kristan, Rozman, Kern, Flezar, Kosnik, Korosec: Complement factor C5a in acute exacerbation of Chronic Obstructive Pulmonary Disease. in Scandinavian journal of immunology 2010
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Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN4895404
Pundir, MacDonald, Kulka: The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production. in Journal of immunology (Baltimore, Md. : 1950) 2015
Human Monoclonal C5AR1 Primary Antibody for FACS - ABIN4895403
Reis, Chen, Sfyroera, Monk, Köhl, Ricklin, Lambris: C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay. in Journal of immunology (Baltimore, Md. : 1950) 2012
C5aR1-KO mice exhibited less renal injury, as evidenced by reduced albuminuria. In contrast, cardiac injury was accelerated with increased cardiac fibrosis and heart weight in C5aR1-deficient mice after ANG II (show AGT Antibodies) infusion. No effect was found on blood pressure. the C5a:C5aR1 axis drives end-organ damage in the kidney but protects from the development of cardiac fibrosis and hypertrophy in experimental hypertension.
This study demonstrated that C5aR1 contributes to the acute inflammatory response elicited by infiltrating immune cells following pilocarpine status epilepticus.
Regulation of complement 5a receptor (C5aR)-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 Antibodies)) depends on galectin-3 (show LGALS3 Antibodies).
The C5a/C5aR pathway is essential for up-regulating SphK1 (show SPHK1 Antibodies) expression through p38 MAPK (show MAPK14 Antibodies) activation in acute liver failure.in mice.
C5a bidirectionally amplifies TLR4 (show TLR4 Antibodies)-mediated NLRP3 (show NLRP3 Antibodies) inflammasome activation in monocytes while suppressing this pathway in macrophages. However, as C5aR1 deficiency attenuates the IL-1beta (show IL1B Antibodies) response to LPS (show TLR4 Antibodies) challenge in vivo, results suggest overall that C5a augments physiologic inflammasome responses.
CYP4F18 (show CYP4F3 Antibodies)-deficient neutrophils exhibit increased chemotaxis to complement component C5a.
showed that C3a (show C3 Antibodies) receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods
Knockout of the C5aR1 attenuated the effect of beta1-AR in the heart, suggesting an association between the beta1-AR and C5aR1, although further investigation is required to determine if this is a direct or causal association
Data (including data from studies in knockout mice) suggest that C5aR/C5aR (complement C5a/anaphylatoxin (show C5 Antibodies) C5a Receptor) signaling pathway is involved in neurocognitive injury in uninfected pups induced by malaria in pregnancy.
Data indicate that C5ar1 activation plays a role in seizure initiation and severity, as well as neuronal degeneration following status epilepticus.
C5aR expression in gastric cancer was associated with cancer progression, liver metastasis, and poor prognosis.
this study shows that downregulation of CD88 after stimulation with IL-8 (show IL8 Antibodies) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 Antibodies) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults
Relation of C5aR expression to tumor development and poor prognosis of the breast cancer patients
The objective of the present study was to validate a receptor occupancy (RO) assay for a human anti-C5aR monoclonal antibody drug candidate, NNC0215-0384 (NN0384)
These data thus suggest that C5aR1 acts as an enhancer of CCR5 (show CCR5 Antibodies)-mediated HIV entry into macrophages, the targeting of which may prove useful to reduce HIV infection by R5 strains.
C5AR and C5L2 (show GPR77 Antibodies)-mediated neutrophil dysfunction is associated with a poor outcome in sepsis.
that C5aR stimulates cell invasion and migration via ERK1/2 (show MAPK1/3 Antibodies)-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells
Inhibition of C5aR1 leads to a significant reduction of CD66b and CD11b (show ITGAM Antibodies) expression indicating a lower neutrophil activation status and block of granule exocytosis.
that rs10853784 of C5aR1 gene are associated with coronary artery disease in Han population of China
96.7% of the metastatic RCCs had C5aR expression, vs. 50.5% of the non-metastatic ones. C5a triggered ERK (show EPHB2 Antibodies)- and PI3Kdependent invasion of the C5aR-expressing renal carcinoma (show TSC2 Antibodies) cells. The C5a-C5aR axis plays a crucial role in renal carcinoma (show TSC2 Antibodies) cell invasion.
Studies provide information regarding distinct structural and functional features that may contribute to the unique pharmacological properties of bovine C5aR.
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
complement component 5a receptor 1
, C5a anaphylatoxin receptor
, G protein-coupled receptor 77
, C5a anaphylatoxin chemotactic receptor 1
, C5a ligand
, complement component 5, receptor 1
, complement component 5 receptor 1
, complement C5a receptor
, anaphylatoxin C5a receptor
, complement component 5 receptor 1 (C5a ligand)
, C5a anaphylatoxin chemotactic receptor