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Complement Factor H-Related 5 (CFHR5) ELISA Kits

CFHR5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Additionally we are shipping Complement Factor H-Related 5 Antibodies (68) and Complement Factor H-Related 5 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CFHR5 81494 Q9BXR6
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Top Complement Factor H-Related 5 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.156 ng/mL 0.625-40 ng/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for Complement Factor H-Related 5 Interaction Partners

Human Complement Factor H-Related 5 (CFHR5) interaction partners

  1. Our study found that rare variants in CFHR5 may contribute to the genetic susceptibility to IgA Nephropathy, which suggests that CFHR5 is an IgA Nephropathy susceptibility gene

  2. Next-generation sequencing of the CFH (show CFH ELISA Kits) region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH (show CFH ELISA Kits)-related genes in the retina or RPE/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR5]

  3. Studies indicate that complement factor H (show CFH ELISA Kits)-related proteins (FHR1 (show CFHR1 ELISA Kits)-5) may enhance complement activation, with important implications for the role of these proteins in disease.

  4. In this study, we identify pentraxin 3 (PTX3 (show PTX3 ELISA Kits)) as a novel ligand of CFHR5

  5. At least two distinct intronic breakpoints within the CFHR5 gene can cause the same mutant CFHR5 protein and C3 glomerulopathy.

  6. A hybrid CFHR2 (show CFHR2 ELISA Kits)-CFHR5 plasma protein, arising from a chromosomal deletion mutation stabilizes the C3 convertase and reduces factor H (show CFH ELISA Kits)-mediated convertase decay.

  7. Recent investigations in London and Cyprus culminated in the identification of another autosomal dominant condition that presents with microscopic haematuria because of heterozygous mutations in the CFHR5 gene--{review}

  8. A potentially pathogenic sequence variation was found in CFHR5 in the patients with atypical hemolytic uremic syndrome.

  9. CFHR5 nephropathy is discussed.

  10. Describe the clinical course, significant variable expressivity, and marked gender difference regarding the development of chronic renal failure in familial C3 glomerulopathy associated with CFHR5 mutations.

Complement Factor H-Related 5 (CFHR5) Antigen Profile

Antigen Summary

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).

Gene names and symbols associated with CFHR5

  • complement factor H-related 5 (CFHR5) antibody
  • CFHL5 antibody
  • CFHR5D antibody
  • FHR-5 antibody
  • FHR5 antibody

Protein level used designations for CFHR5

complement factor H-related protein 5 , factor H-related protein 5

GENE ID SPECIES
81494 Homo sapiens
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