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anti-Crystallin, gamma C (CRYGC) Antibodies

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. Additionally we are shipping CRYGC Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CRYGC 1420 P07315
CRYGC 24277 P02529
CRYGC 12966 Q61597
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Top anti-CRYGC Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CRYGC Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 ug whole cell lysate) A:A431, 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB Figure 1. Gamma-crystallin C antibody staining of A431 (A) whole cell lysate (30 µg) at 1/1000 dilution, 12% SDS PAGE. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated WB Crystallin Gamma C antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

CRYGC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CRYGC Antibodies

  1. Cow (Bovine) Polyclonal CRYGC Primary Antibody for WB - ABIN2774014 : Gonzalez-Huerta, Messina-Baas, Cuevas-Covarrubias: A family with autosomal dominant primary congenital cataract associated with a CRYGC mutation: evidence of clinical heterogeneity. in Molecular vision 2007 (PubMed)

More Antibodies against CRYGC Interaction Partners

Human Crystallin, gamma C (CRYGC) interaction partners

  1. the G129C mutation in gammaC-crystallin, which is associated with autosomal dominant congenital nuclear cataract, perturbed the unfolding process by promoting the accumulation of two distinct aggregation-prone intermediates under mild denaturing conditions.

  2. Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8 (show GJA8 Antibodies), CRYGC, PAX6 (show PAX6 Antibodies) and CYP1B1 (show CYP1B1 Antibodies).

  3. We confirm that congenital cataract is associated with a CRYGC gene mutation.

  4. identified a CRYAA (show CRYAA Antibodies) mutation in family A and a CRYGC mutation in family B with congenital cataract

  5. A nonsense mutation c.471G>A in CRYGC is associated with autosomal dominant congenital nuclear cataracts and microcornea in a Chinese pedigree.

  6. Molecular modeling and spectroscopic studies indicated that the mutation impaired the tertiary structure of gamma C crystallin by modifying the H-bonding network in the C-terminal domain.

  7. Two novel nonsynonymous variations and four reported variations in CRYAB (show CRYAB Antibodies), CRYGC, CRYGD (show CRYGD Antibodies), and GJA8 (show GJA8 Antibodies), were observed.

  8. In gammaD-crystallin, methylation is exclusively at Cys (show DNAJC5 Antibodies) 110, whereas in gammaC- and gammaB-crystallins, the principal methylation site is Cys (show DNAJC5 Antibodies) 22 with minor methylation at Cys (show DNAJC5 Antibodies) 79

  9. the loss of interactions of T5P mutant of the gammaC-crystallin with other crystallins may play a larger role than the protection afforded by chaperone-like activity in Coppock-like cataract.

  10. This is the first case of phenotypic heterogeneity in the primary congenital cataract specifically associated with the R168W mutation in the CRYGC gene.

Cow (Bovine) Crystallin, gamma C (CRYGC) interaction partners

Mouse (Murine) Crystallin, gamma C (CRYGC) interaction partners

  1. a 1-bp deletion in gammaC-crystallin leads to cataract.

  2. presence of measurable interactions between MIP26 (show MIP Antibodies) and all crystallins, with the extent of interactions decreasing from alphaA- and alphaB-crystallin (show CRYAB Antibodies) to betaB2- and gammaC-crystallin.

CRYGC Antigen Profile

Protein Summary

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Gene names and symbols associated with CRYGC

  • crystallin, gamma C (crygc) antibody
  • crystallin, gamma C (CRYGC) antibody
  • crystallin, gamma C (LOC100354942) antibody
  • crystallin, gamma C (LOC100358871) antibody
  • crystallin, gamma C (Crygc) antibody
  • CCL antibody
  • Cryg antibody
  • Cryg-5 antibody
  • Cryg3 antibody
  • CTRCT2 antibody
  • Len antibody
  • MGC84008 antibody

Protein level used designations for CRYGC

crystallin, gamma C , gamma-crystallin C , crystallin, gamma-3 , gamma-C-crystallin , gamma-crystallin 2-1 , gamma-crystallin 3 , gamma-crystallin IIIA , gammaC-crystallin , crystallin, gamma polypeptide 3

GENE ID SPECIES
444574 Xenopus laevis
737363 Pan troglodytes
100354942 Oryctolagus cuniculus
100358871 Oryctolagus cuniculus
1420 Homo sapiens
100126770 Canis lupus familiaris
281722 Bos taurus
24277 Rattus norvegicus
12966 Mus musculus
100337641 Cavia porcellus
709553 Macaca mulatta
Selected quality suppliers for anti-CRYGC (CRYGC) Antibodies
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