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Cut-Like Homeobox 1 Proteins (CUX1)

The protein encoded by CUX1 contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. Additionally we are shipping Cut-Like Homeobox 1 Antibodies (106) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CUX1 56693 Q9CYD3
CUX1 1523 Q13948,P39880
Rat CUX1 CUX1 116639  
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Top Cut-Like Homeobox 1 Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CUX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for Cut-Like Homeobox 1 (CUX1) Interaction Partners

Mouse (Murine) Cut-Like Homeobox 1 (CUX1) interaction partners

  1. Cux1 is essential for the developmental modulation of intrinsic excitability and the switch to a Kv1 (show KCNA5 Proteins)-dependent firing mode necessary for interhemispheric innervation.

  2. Findings reinforce the link between oxidative DNA damage and cellular senescence and suggest that the role of CUX1 as an accessory factor in DNA repair will be critical in physiological situations that generate higher levels of reactive oxygen species.

  3. Results suggest that by their differential effects on basal and apical dendrites, Cux1 and Cux2 (show CUX2 Proteins) can promote the integration of layer II-III neurons in the intracortical networks in highly specific ways

  4. Results show that Cux1 is expressed in cerebellar granule cell precursors and downregulated as they terminally differentiate; suggests some limitations of established medulloblastoma cell lines and mouse models

  5. CUX1 functions in base excision repair as an ancillary factor for the 8-oxoG-DNA glycosylase, OGG1 (show OGG1 Proteins).

  6. This substitution abolished P3h1 (show LEPRE1 Proteins) activity but retained ability to form a complex with Crtap (show CRTAP Proteins) and thus the collagen chaperone function.

  7. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro.

  8. overexpression of active CUTL1 significantly resulted in increased cancer tissue response to chemotherapy and therefore inhibited growth, whereas knockdown of CUTL1 conferred resistance to chemotherapy.

  9. CUX1, a direct target of microRNA122, is a common central mediator of two effects of microRNA122 disregulation; alpha-fetoprotein (show AFP Proteins) upregulation and an aggressive phenotype in hepatocellular carcinoma.

  10. Increased Cux1 expression associated with apoptosis is a common feature of late stage cyst progression in both the cpk and Pkd1 (show PKD1 Proteins)(CD) mouse models of polycystic kidney disease.

Human Cut-Like Homeobox 1 (CUX1) interaction partners

  1. Results show that Cux1 is expressed in cerebellar granule cell precursors and downregulated as they terminally differentiate; coexpression analysis in human medulloblastomas suggests another function related to DNA integrity and stability

  2. High CUX1 expression is associated with metastasis in pancreatic neuroendocrine neoplasms.

  3. Authors identified CUX1 as an important modulator of the TAMs phenotype and function by modulating NF-kappaB (show NFKB1 Proteins)-dependent cytokines.

  4. CASP is specifically cleaved by granzymeB.

  5. Suggest that CUTL1 may regulate the proliferation of malignant melanoma by modulating the expression of cell cycle-related proteins.

  6. CUX1 expression is associated with tumour progression and tumor burden. [Review]

  7. CASP has a direct role in the secretion of IFN-gamma (show IFNG Proteins), and NK cell motility and ability to kill tumor cells. CASP polarizes to the leading edge of migrating NK cells, and to the immunological synapse when engaged with tumor cells.

  8. Loss of CUX1 is associated with myeloid neoplasms.

  9. Cux1 is a tumor suppressor and inactivating CUX1 mutations promote tumorigenesis.

  10. Our results provide the first evidence that polymorphisms of the CUX1 gene may be associated with response to antidepressant treatment in Japanese patients with MDD.

Cut-Like Homeobox 1 (CUX1) Protein Profile

Protein Summary

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.

Gene names and symbols associated with Cut-Like Homeobox 1 Proteins (CUX1)

  • cut-like homeobox 1 (CUX1)
  • cut-like homeobox 1 (cux1)
  • cut-like homeobox 1a (cux1a)
  • cut-like homeobox 1 (ML5_2169)
  • cut-like homeobox 1 (LOC100231967)
  • cartilage associated protein (Crtap)
  • cut-like homeobox 1 (Cux1)
  • cytohesin 1 interacting protein (CYTIP)
  • protein CASP (CASP)
  • 5730529N23Rik protein
  • AA407197 protein
  • AtCASP protein
  • B3-1 protein
  • CASP protein
  • CCAAT-displacement protein alternatively spliced product protein
  • CDP protein
  • CDP/Cut protein
  • CDP1 protein
  • Clox protein
  • COY1 protein
  • Cutl1 protein
  • Cux protein
  • Cux-1 protein
  • Cux/CDP protein
  • CYBR protein
  • CYTHIP protein
  • DKFZp469C1221 protein
  • GOLIM6 protein
  • HE protein
  • Leprel3 protein
  • mKIAA4047 protein
  • Nbla10317 protein
  • p75 protein
  • p100 protein
  • p110 protein
  • p200 protein
  • Phox2 protein
  • PSCDBP protein
  • si:ch211-251d10.5 protein
  • wu:fi22b07 protein
  • wu:fk35a11 protein

Protein level used designations for Cut-Like Homeobox 1 Proteins (CUX1)

cut-like homeobox 1 , (clone C8) CASP , cut-like 1, CCAAT displacement protein , CCAAT displacement protein , protein CASP , homeobox protein cut-like 1-like , fi22b07 , cartilage-associated protein , cut homolog , golgi integral membrane protein 6 , homeobox protein cux-1 , putative protein product of Nbla10317 , Cux/CDP homeoprotein , cut-like 1 , homeobox protein cut-like 1 , CDP , CDP2 , cbp HE , cytohesin binder and regulator , cytohesin binding protein HE , cytohesin-1 interacting protein , cytohesin-associated scaffolding protein , cytohesin-binding protein HE , cytohesin-interacting protein , pleckstrin homology Sec7 and coiled-coil domains-binding protein , pleckstrin homology, Sec7 and coiled-coil domains, binding protein , pleckstrin homology, Sec7 and coiled/coil domains, binding protein

GENE ID SPECIES
396358 Gallus gallus
450166 Pan troglodytes
472471 Pan troglodytes
523683 Bos taurus
100060510 Equus caballus
100171552 Pongo abelii
100412663 Callithrix jacchus
100479940 Ailuropoda melanoleuca
100488175 Xenopus (Silurana) tropicalis
100521258 Sus scrofa
797445 Danio rerio
10057675 Micromonospora sp. L5
100231967 Taeniopygia guttata
100543115 Meleagris gallopavo
56693 Mus musculus
1523 Homo sapiens
13047 Mus musculus
116639 Rattus norvegicus
489821 Canis lupus familiaris
9595 Homo sapiens
821377 Arabidopsis thaliana
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