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Cyclin T1 (CCNT1) ELISA Kits

CCNT1 encodes a member of the highly conserved cyclin C subfamily. Additionally we are shipping Cyclin T1 Antibodies (58) and Cyclin T1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CCNT1 904 O60563
CCNT1 12455 Q9QWV9
CCNT1 315291  
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More ELISA Kits for Cyclin T1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Cyclin T1 (CCNT1) interaction partners

  1. We conclude that a subset of non-paused, pre-cellular genes are among the most susceptible to reduced P-TEFb (show CDK9 ELISA Kits), SEC and Mediator levels in Drosophila embryos.

  2. following P-TEFb (show CDK9 ELISA Kits) inhibition, most polymerases were restricted to within 150 bp of the transcription initiation site of the active Drosophila melanogaster Hsp70 gene, and live-cell imaging demonstrated that these polymerases were stably associated

Human Cyclin T1 (CCNT1) interaction partners

  1. the introduction of HIV-1 Tat (show TAT ELISA Kits) and Mg12+ ion resulted in the active site architectural characteristics of phosphorylated CDK9 (show CDK9 ELISA Kits)/cyclin T1 complex

  2. AFF4 (show AFF4 ELISA Kits) is positioned to make unexpected direct contacts with HIV Tat (show TAT ELISA Kits), and Tat (show TAT ELISA Kits) enhances P-TEFb/CCNT1 affinity for AFF4 (show AFF4 ELISA Kits).

  3. Plk1 (show PLK1 ELISA Kits) negatively regulates the RNA polymerase II-dependent transcription through inhibiting the activity of cyclin T1/Cdk9 (show CDK9 ELISA Kits) complex.

  4. The sequence domain of human cytomegalovirus pUL97 responsible for the interaction with cyclin T1 was between amino acids 231-280.

  5. the release of P-TEFb from the 7SK snRNP (show LSM2 ELISA Kits) led to increased synthesis of HEXIM1 (show HEXIM1 ELISA Kits) but not HEXIM2 (show HEXIM2 ELISA Kits)

  6. All of the hCD4/R5/cT1 (show CTF1 ELISA Kits) mice developed disseminated infection of tissues that included the spleen, small intestine, lymph nodes and lungs after intravenous injection with an HIV-1 infectious molecular clone

  7. positive transcription elongation factor b (P-TEFb (show CDK9 ELISA Kits), made of CDK9 (show CDK9 ELISA Kits) and CycT1) is released from its inhibitory complex by histone deacetylase (show HDAC1 ELISA Kits) inhibitors, which also activate HIV transcription

  8. CYCT1b is a newly identified cyclin T1 splice variant whose expression leads to direct inhibition of TAT (show TAT ELISA Kits)-transactivated transcription of the HIV-1 LTR promoter

  9. Structural determination of a short-lived conformational state between CCNT1 and CDK9 (show CDK9 ELISA Kits) that is adopted during the phosphorylation cycle.

  10. The authors find that resting CD4 (show CD4 ELISA Kits)(+) T cells, whether naive or memory and independent of their HIV infection status, have low levels of Cyclin T1 and T-loop-phosphorylated CDK9 (show CDK9 ELISA Kits), which increase upon activation.

Mouse (Murine) Cyclin T1 (CCNT1) interaction partners

  1. Data show that the minimal 90-amino acid AF9 fragment in MLL-AF9 retains an ability to form higher order complexes with AF4*P-TEFb and with DOT1.

  2. Data show that the CDK9 (show CDK9 ELISA Kits) and cyclin T1 subunits of P-TEFb are present in mouse oocytes and preimplantation embryos, and that CDK9 (show CDK9 ELISA Kits) is essential for embryonic genome activation in the mouse.

  3. Cyclin T1 oncogenic function and suggest a role for this protein in controlling cell cycle probably via Rb/E2F1 (show E2F1 ELISA Kits) pathway.

  4. CDK9 (show CDK9 ELISA Kits) has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of cyclin T1 promotes its nuclear localization.

  5. P-TEFb is a key mediator of Myc (show MYC ELISA Kits) activated transcription by stimulating elongation

  6. Tat (show TAT ELISA Kits) and trans-activation-responsive (TAR (show RBM8A ELISA Kits)) RNA-independent induction of HIV-1 long terminal repeat by this protein requires Sp1 (show SP1 ELISA Kits).

  7. cyclin T1 binds with granulin (show GRN ELISA Kits) to inhibit transcription

  8. location of the cyclin T1 gene regulatory elements is male germ cell-specific

  9. These data link the P-TEFb equilibrium to the intracellular transcriptional demand and proliferative/differentiated states of cells.

  10. knockdown of CycT1 from P-TEFb abolishes both of the different chromatin loops regulating CD4 (show CD4 ELISA Kits) expression

Cyclin T1 (CCNT1) Antigen Profile

Antigen Summary

This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Cyclin T1 (CCNT1) ELISA Kits

  • Cyclin T (CycT) antibody
  • cyclin T1 (CCNT1) antibody
  • cyclin T1 (ccnt1) antibody
  • cyclin T1 (LOC100352150) antibody
  • cyclin T1 (Ccnt1) antibody
  • 2810478G24Rik antibody
  • AI115585 antibody
  • anon-74EFc antibody
  • CCNT antibody
  • CG6292 antibody
  • Cyclin-T1 antibody
  • CycT1 antibody
  • Dmcyclin T antibody
  • Dmel\\CG6292 antibody
  • dT antibody
  • fi75b02 antibody
  • HIVE1 antibody
  • ORE-14 antibody
  • P-TEFb antibody
  • p124 antibody
  • si:dkey-18f23.10 antibody
  • wu:fi75b02 antibody

Protein level used designations for Cyclin T1 (CCNT1) ELISA Kits

CG6292-PA , CG6292-PB , CG6292-PC , CG6292-PD , CycT-PA , CycT-PB , CycT-PC , CycT-PD , CyclinT , cyclin T , cyclin T1 , cyclin T2 , dCyclin T , cyclin-T1-like , CDK9-associated C-type protein , cyclin C-related protein , cyclin-T1 , human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1 , cyclin-T , cycT1 , cyclin T1 protein

39961 Drosophila melanogaster
707754 Macaca mulatta
100170179 Xenopus (Silurana) tropicalis
100409876 Callithrix jacchus
100352150 Oryctolagus cuniculus
100583185 Nomascus leucogenys
904 Homo sapiens
12455 Mus musculus
315291 Rattus norvegicus
334465 Danio rerio
734952 Xenopus laevis
486564 Canis lupus familiaris
407194 Bos taurus
100033893 Equus caballus
450146 Pan troglodytes
100860835 Capra hircus
101106415 Ovis aries
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