You are viewing an incomplete version of our website. Please click to reload the website as full version.

Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) ELISA Kits

The protein encoded by CDK5R1 (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5)\; the activation of CDK5 is required for proper development of the central nervous system. Additionally we are shipping CDK5R1 Antibodies (96) and CDK5R1 Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CDK5R1 8851 Q15078
CDK5R1 12569 P61809
CDK5R1 116671 P61810
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top CDK5R1 ELISA Kits at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 6 Days
$528.57
Details
Rat
0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Human
78-5000 pg/mL 96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

More ELISA Kits for CDK5R1 Interaction Partners

Zebrafish Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) interaction partners

  1. p35 likely acts downstream of egr1 (show EGR1 ELISA Kits) to control the differentiation of Parvalbumin (show PVALB ELISA Kits)+ amacrine cells.

Pig (Porcine) Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) interaction partners

  1. CDK5 (show CDK5 ELISA Kits) mRNA reaches the highest level in cerebral cortex at two months of age and in cerebellum and liver at 4 months of age, respectively, whereas the peak level of CDK5R1 was observed in both cerebral cortex and cerebellum at two months of age

Human Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) interaction partners

  1. Under cell-free in vitro conditions, p35 (show ANXA1 ELISA Kits) is covalently modified by SUMO1 (show SUMO1 ELISA Kits). SUMO2 (show SUMO2 ELISA Kits) is conjugated to p35 (show ANXA1 ELISA Kits) in cells. The 2 major SUMO acceptor lysines in p35 (show ANXA1 ELISA Kits) are K246 and K290. Different degrees of oxidative stress resulted in differential p35 (show ANXA1 ELISA Kits) sumoylation.

  2. Cdk5 (show CDK5 ELISA Kits)/p35 (show ANXA1 ELISA Kits) is required for motor learning and involved in long-term synaptic plasticity.

  3. Expression of p35 (show ANXA1 ELISA Kits) is upregulated in human pituitary adenomas.

  4. These results reveal a physiological role of p25 (show LCN2 ELISA Kits) production in synaptic plasticity and memory and provide new insights into the function of p25 (show LCN2 ELISA Kits) in Abeta (show APP ELISA Kits)-associated neurotoxicity and Alzheimer's disease-like pathology.

  5. Structural basis for the different stability and activity between the Cdk5 (show CDK5 ELISA Kits) complexes with p35 (show ANXA1 ELISA Kits) and p39 (show JUN ELISA Kits) activators.

  6. Reduced p35 (show ANXA1 ELISA Kits) basal content and down--regulation of CDK5 (show CDK5 ELISA Kits)/p35/p25 by antipsychotics are demonstrated in postmortem prefrontal cortex of schizophrenic subjects.

  7. The present study dissects the role of 3 single nucleotide polymorphisms (rs334558 and rs6438552 of GSK3B, and rs735555 of CDK5R1) in Parkinson's disease pathogenesis among eastern Indians.

  8. p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity.

  9. The decrease in membrane-associated p35 (show ANXA1 ELISA Kits) in socially isolated transgenic mice reduces associated levels of p35 (show ANXA1 ELISA Kits), alpha-CaMKII, and GluR1 (show GRIA1 ELISA Kits) and leads to endocytosis of AMPA (show GRIA3 ELISA Kits) receptors.

  10. CDK5 (show CDK5 ELISA Kits)/p35 (show ANXA1 ELISA Kits) may represent a biomarker for prognosis in patients with non-small cell lung cancer

Mouse (Murine) Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) interaction partners

  1. The transiently active CDK5 (show CDK5 ELISA Kits)-p35 complexes limited the LPS (show TLR4 ELISA Kits)-stimulated phosphorylation and activation of various mitogen-activated protein kinases (MAPKs), thereby preventing the premature production of SOCS3 (suppressor of cytokine signaling 3 (show SOCS3 ELISA Kits))

  2. Cdk5 (cyclin-dependent kinase 5 (show CDK5 ELISA Kits)) requires p35 regulatory subunit (Cdk5r1) for activation; data suggest Cdk5r1 stability regulates Cdk5 (show CDK5 ELISA Kits) activity in neurons; Cdk5r1 is rapidly degraded by 2 proteasome methods, ubiquitination-dependent and -independent.

  3. These data suggest p35 and p39 (show ATP6V0D1 ELISA Kits) have specific and overlapping roles in oligodendrocyte development, some of which may be independent of Cdk5 (show CDK5 ELISA Kits) activation.

  4. Studied the effect of reduced levels of p25 and p35, two proteins required for cdk5 (show CDK5 ELISA Kits) activation, on striatal neurodegeneration using mice with targeted deletion of p35.

  5. p35 interacts with NIF-1 (show ZNF335 ELISA Kits) and regulates the subcellular localization of the protein independent of Cdk5 (show CDK5 ELISA Kits)-dependent phosphorylation. ...reveal a new mechanism of p35 in transcriptional regulation that does not require the kinase activity of Cdk5 (show CDK5 ELISA Kits)

  6. Cdk5 (show CDK5 ELISA Kits)/p35 regulates spatial learning and memory.

  7. Our findings suggest that p35/Rac1 signaling is critical in the CDK5 (show CDK5 ELISA Kits) silencing-induced neuroprotection against glutamate (show GRIN1 ELISA Kits) neurotoxicity

  8. provide a mechanistic explanation that Sig-1Rs help maintain proper tau phosphorylation by potentially carrying and providing myristic acid to p35 for enhanced p35 degradation to circumvent the formation of overreactive cdk5/p25

  9. This report shows that herpes simplex virus 1 increases p35 levels, changes the primary localization of CDK-5 (show CDK5 ELISA Kits) from the nucleus to the cytoplasm, and enhances CDK-5 (show CDK5 ELISA Kits) activity during lytic or acute infection.

  10. the effects of p25, although normally attributed to activate CDK5, may be mediated in part by elevated GSK3beta activity.

Cow (Bovine) Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) interaction partners

  1. Data suggest that up-regulation of S100A8 (show S100A8 ELISA Kits) and S100A9 (show S100A9 ELISA Kits) is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet.

CDK5R1 Antigen Profile

Antigen Summary

The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5)\; the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer's disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer's disease.

Gene names and symbols associated with CDK5R1

  • cyclin-dependent kinase 5, regulatory subunit 1 (p35) (cdk5r1-a) antibody
  • cyclin-dependent kinase 5, regulatory subunit 1b (p35) (cdk5r1b) antibody
  • cyclin-dependent kinase 5, regulatory subunit 1 (p35) (CDK5R1) antibody
  • cyclin-dependent kinase 5, regulatory subunit 1 (p35) (Cdk5r1) antibody
  • related RAS viral (r-ras) oncogene homolog (Rras) antibody
  • S100 calcium binding protein A9 (S100A9) antibody
  • transmembrane emp24-like trafficking protein 10 (yeast) (Tmed10) antibody
  • tumor protein, translationally-controlled 1 (TPT1) antibody
  • 1110014C03Rik antibody
  • CDK5P35 antibody
  • Cdk5r antibody
  • CDK5R1 antibody
  • D11Bwg0379e antibody
  • NCK5A antibody
  • p23 antibody
  • p24delta1 antibody
  • p25 antibody
  • P25/P35 antibody
  • p35 antibody
  • p35nck5a antibody
  • PCHK23 antibody
  • TCTP antibody
  • Tmp21 antibody
  • Xp35.1 antibody
  • zgc:92814 antibody

Protein level used designations for CDK5R1

cyclin-dependent kinase 5, regulatory subunit 1 (p35) , cyclin-dependent kinase 5 regulatory subunit , cyclin-dependent kinase 5 activator 1 , cyclin-dependent kinase 5 regulatory subunit 1 , CDK5 activator 1 , TPKII regulatory subunit , neuronal CDK5 activator , regulatory partner for CDK5 kinase , tau protein kinase II 23kDa subunit , cyclin-dependent kinase 5, regulatory subunit (p35) 1 , p23 , tau protein kinase II 23 kDa subunit , Harvey rat sarcoma oncogene, subgroup R , Harvey rat sarcoma virus oncogene, subgroup R , Ras-related protein R-RAS (P23) , ras-related protein R-Ras , BEE22 , S100 calcium-binding protein A9 , calgranulin-B , neutrophil cytosolic 23 kDa protein , protein S100-A9 , 21 kDa transmembrane-trafficking protein , p24 family protein delta-1 , transmembrane emp24 domain-containing protein 10 , transmembrane protein Tmp21 , transmembrane trafficking protein , growth-related translationally controlled tumor protein , growth-related translationally-controlled tumor protein , translationally-controlled tumor protein homolog

GENE ID SPECIES
373685 Xenopus laevis
436788 Danio rerio
491154 Canis lupus familiaris
714274 Macaca mulatta
747897 Pan troglodytes
100113467 Sus scrofa
8851 Homo sapiens
12569 Mus musculus
116671 Rattus norvegicus
282173 Bos taurus
361568 Rattus norvegicus
532569 Bos taurus
68581 Mus musculus
396363 Gallus gallus
Selected quality suppliers for CDK5R1 (CDK5R1) ELISA Kits
Did you look for something else?