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Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Proteins (CHORDC1)

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Additionally we are shipping Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHORDC1 26973 Q9UHD1
CHORDC1 315447 D4A4T9
CHORDC1 66917 Q9D1P4
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Top Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,889.33
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,893.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,893.00
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,893.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,902.17
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,924.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CHORDC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) Interaction Partners

Human Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) interaction partners

  1. suppression of miR (show MLXIP Proteins)-26b expression up-regulates its target gene CHORDC1, which increases HBV enhancer/promoter activities and promotes viral transcription, gene expression, and replication

  2. morgana causes PTEN destabilization, by inhibiting ROCK activity

  3. Chp-1 (show CHP Proteins) and melusin (show ITGB1BP2 Proteins) can interact with cochaperones PP5 (show PPP5C Proteins) and Sgt1 (show SUGT1 Proteins) and with each other in an ATP-dependent manner

  4. A novel ADP-dependent HSP90 (show HSP90 Proteins) interaction with the cysteine- and histidine-rich domain (CHORD)-containing protein CHORDC1, is characterized.

  5. This paper described the cloning of a barley CHORD containing protein, but it also described the CHORD containing proteins in other species including human and characterized the CHORD domains.

Mouse (Murine) Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) interaction partners

  1. Loss of Morgana expression is associated with drug resistance and chronic myeloid leukemia (show BCL11A Proteins).

  2. morgana causes PTEN destabilization, by inhibiting ROCK activity

  3. Chp-1 and melusin (show ITGB1BP2 Proteins) can interact with cochaperones PP5 (show PPP5C Proteins) and Sgt1 (show SUGT1 Proteins) and with each other in an ATP-dependent manner

  4. Overexpression of morgana/CHP-1 in NIH3T3 cells leads to the increased stress resistance of the cells.

  5. Morgana/chp-1 downregulation promotes the interaction between ROCK II (show ROCK2 Proteins) and nucleophosmin (show NPM1 Proteins), leading to an increased ROCK II (show ROCK2 Proteins) kinase activity, which results in centrosome amplification.

  6. Full length sequence, gene structure and expression of Chp-1.

  7. The first biochemical evidence demonstrating that mammalian Chp-1 is a novel Hsp90 (show HSP90 Proteins)-interacting protein.

  8. results suggest that Chordc1 mRNA is under complex and widespread transcriptional regulation during development and implicate Chordc1 in circadian and/or homeostatic mechanisms in mammalian brain.

Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) Protein Profile

Protein Summary

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis (By similarity).

Gene names and symbols associated with CHORDC1

  • cysteine and histidine-rich domain (CHORD)-containing 1 (CHORD)
  • cysteine and histidine-rich domain (CHORD)-containing 1 (chordc1)
  • cysteine and histidine-rich domain (CHORD)-containing 1 (CHORDC1)
  • cysteine and histidine-rich domain (CHORD)-containing 1 (Chordc1)
  • cysteine and histidine-rich domain (CHORD) containing 1 (CHORDC1)
  • cysteine and histidine-rich domain (CHORD) containing 1 (chordc1)
  • cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1 (chordc1)
  • cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 (Chordc1)
  • integrin beta 1 binding protein (melusin) 2 (ITGB1BP2)
  • 1110001O09Rik protein
  • AA409036 protein
  • Chp-1 protein
  • CHP1 protein
  • MGC89160 protein
  • morgana protein
  • NV16801 protein
  • zgc:63894 protein

Protein level used designations for CHORDC1

cysteine and histidine-rich domain (CHORD)-containing 1 , cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1 , CHORD domain-containing protein 1 , cysteine and histidine-rich domain-containing protein 1 , protein morgana , CHORD-containing protein 1 , CHP-1 , chord domain-containing protein 1 , cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 , CHORD containing protein-1 , morgana , melusin

GENE ID SPECIES
412067 Apis mellifera
448329 Xenopus (Silurana) tropicalis
466743 Pan troglodytes
694312 Macaca mulatta
100120564 Nasonia vitripennis
100172001 Pongo abelii
414542 Xenopus laevis
419009 Gallus gallus
26973 Homo sapiens
476773 Canis lupus familiaris
100134961 Sus scrofa
505144 Bos taurus
315447 Rattus norvegicus
393310 Danio rerio
66917 Mus musculus
422208 Gallus gallus
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