Cysteine-S-conjugate beta-Lyase Proteins (CCBL1)

CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. Additionally we are shipping CCBL1 Antibodies (70) and CCBL1 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CCBL1 CCBL1 70266 Q8BTY1
CCBL1 883 Q16773
CCBL1 311844 Q08415
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Top CCBL1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Bioactivity measured with Activity Assay Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
$444.37
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,197.33
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 15 to 18 Days
$688.00
Details

CCBL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus)

More Proteins for Cysteine-S-conjugate beta-Lyase (CCBL1) Interaction Partners

Mouse (Murine) Cysteine-S-conjugate beta-Lyase (CCBL1) interaction partners

  1. One is the native structure with the cofactor in the PLP (show C3 Proteins) form bound to Lys247 with the highest resolution yet available for KAT (show NEK1 Proteins)-I at 1.28 A resolution, and the other with the general PLP (show C3 Proteins)-dependent aminotransferase inhibitor, aminooxyacetate (AOAA) covalently bound to the cofactor at 1.54 A.

  2. KAT (show NEK1 Proteins) I inhibited by equimolar tryptophan and half-life is 69.7 minutes at 65 degree C.

Human Cysteine-S-conjugate beta-Lyase (CCBL1) interaction partners

  1. CH(3 (show SOX3 Proteins))Hg-S-Cys (show DNAJC5 Proteins) and Cys (show DNAJC5 Proteins)-S-Hg-S-Cys (show DNAJC5 Proteins) are substrates and reversible inhibitors of GTK (show FRK Proteins).

  2. major biological roles of glutamine transaminase K are to maintain low levels of phenylpyruvate and to close the methionine salvage pathway--REVIEW

  3. We found elevated cerebellar KAT-1 activities in post-mortem brain samples from schizophrenic versus normal individuals.

  4. alpha-keto acids generated by transamination/l-amino acid oxidase (show IL4I1 Proteins) activity of the two catechol cysteine S-conjugates are unstable

CCBL1 Protein Profile

Protein Summary

This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

Gene names and symbols associated with CCBL1

  • cysteine conjugate-beta lyase 1 (Ccbl1)
  • cysteine conjugate-beta lyase, cytoplasmic (CCBL1)
  • cysteine conjugate-beta lyase, cytoplasmic (Ccbl1)
  • 2010009K05Rik protein
  • AI182306 protein
  • GTK protein
  • KAT1 protein
  • KATI protein

Protein level used designations for CCBL1

cysteine-S-conjugate beta-lyase , cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) , glutamine transaminase K , glutamine--phenylpyruvate transaminase , kynurenine aminotransferase I , kynurenine--oxoglutarate transaminase 1 , kynurenine--oxoglutarate transaminase I , beta-lysase, kidney , cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) , glutamine-phenylpyruvate aminotransferase , kyneurenine aminotransferase , cysteine conjugate-beta lyase 1 , kynurenine aminotransferase/glutamine transaminase K , kynurenine--oxoglutarate transaminase 1, mitochondrial

GENE ID SPECIES
70266 Mus musculus
883 Homo sapiens
311844 Rattus norvegicus
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