Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by CYB5A is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Additionally we are shipping Cytochrome B5 Type A (Microsomal) Kits (21) and Cytochrome B5 Type A (Microsomal) Proteins (13) and many more products for this protein.
Showing 10 out of 104 products:
Human Monoclonal CYB5A Primary Antibody for IHC (p), ELISA - ABIN514807
Ming, Pham, Deb, Chin, Kharmate, Adomat, Beheshti, Locke, Guns: Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo. in The Journal of steroid biochemistry and molecular biology 2014
Demonstration of the physiologic importance of cytochrome b5 activating the 17,20-lyase reaction and the production of 19-carbon sex steroids from 21-carbon precursors in mice.
Cytochrome b5 and cytokeratin 17 (show KRT17 Antibodies) are biomarkers in bronchoalveolar fluid signifying onset of acute lung injury.
the observation of weak and nonspecific interactions between CYP2B4 and cytb5 in micelles suggests that lipid bilayer structures and low curvature membrane surface are preferable for CYP2B4-cytb5 complex formation.
Data suggest that the cytb5-cytP4502B4 complex structure will help unravel the mechanism by which cytb5 regulates catalysis by cytP4502B4.
Two different types of cytochrome b5 orientations are present within a MFO system: the first allowing potential cytochrome b5 electron donation to P450 (show POR Antibodies), the second one inducing cytochrome b5 modulation of P450 (show POR Antibodies) structural changes.
This study constructed a model of the membrane-bound full-length human P450 1A2-cyt b5 complex. The model was assembled from several parts using a multiscale modeling approach covering all-atom and coarse-grained molecular dynamics (MD).
We conclude that cytochrome b5 can influence the electronic conductivity of cytochrome P450c17 (show CYP17A1 Antibodies) via allosteric, protein-protein interactions.
Variants in CYB5A and CYB5R3 (show CYB5R3 Antibodies) should be considered in the evaluation of breast cancer risk in African American women.
CYB5A is the first RA susceptibility gene involved in androgen synthesis. Our functional analysis of SNP rs1790834 indicates that it contributes to the sex bias observed in RA.
both area and ratio of 3betaHSD (show HSD3B1 Antibodies) and CYB5A double positive cells, which could represent the hybrid cells of zona fasciculate and zona reticularis, are correlated with adrenal development and could influence age-related serum androstenedione levels.
Two acidic residues, Glu (show DCTN1 Antibodies)-48 and Glu (show DCTN1 Antibodies)-49, of cytochrome b5 are essential for stimulating the 17,20-lyase activity of CYP17A1 (show CYP17A1 Antibodies).
raises the possibility that inhibition of CYB5A-deregulated downstream pathways, such as those involving TRAF6 (show TRAF6 Antibodies), may favor autophagy-mediated cancer cell death in selected subgroups of patients
CYB5A, which has a role in stearyl-CoA-desaturase activity, and RNF10 (show RNF10 Antibodies), with an unknown role in weight regulating pathways, associated with adiposity and nominally increased the risk for T2D in American Indians.
Cytochrome b5 seems to play the key role in the formation of lipid-radical cycles in membranes.
Results define CYB5A as a novel prognostic factor for PDAC that exerts its tumor-suppressor function through autophagy induction and TRAF6 (show TRAF6 Antibodies) modulation.
Searching the porcine CYB5 gene for mutations, examine its expression, and identify genetic polymorphism in terms of androstenone levels in testis.
the c.-8G>T SNP in the CYB5A gene has a significant but modest effect on boar taint in male pigs and could be useful in some breeds as part of a panel of SNP markers in a marker-assisted selection programme to produce low boar taint pigs
These results demonstrate the differential effects of two forms of CYB5 on the three activities of porcine CYP17A1 (show CYP17A1 Antibodies) and show that CYB5B (show CYB5B Antibodies) does not stimulate the andien-beta synthase activity of CYP17A1 (show CYP17A1 Antibodies).
The study computes electron transfer rates for the [myoglobin (show MB Antibodies)(wt), cytochrome b5] complex.
The solution structure of the oxidized cytochrome b(5) mutant V61H.
the effects on the heme microenvironment of cytochrome b(5) caused by the mutation from Val45 to Tyr45, His45 and Glu45
Results from three combined experiments demonstrate that the conserved negatively charged region of cytb5 surrounding the solvent-exposed heme edge is involved in the binding interaction with horse heart cytochrome c (show CYCS Antibodies).
From a series of site-directed mutations on Cyt b5 this report assesses the contributions of amino acid residues that are expected to influence the docking and electron transfer (ET) between Cyt b5 and horse heart Cyt c (show CYCS Antibodies).
simulations provided qualitative microscopic explanations of many of the differences in physical properties between outer mitochondrial membrane CYB5 isoform and microsomal CYB5 and two mutants in terms of localized changes in structure and flexibility
It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5).
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
, cytochrome b5 type A (microsomal)
, type 1 cyt-b5
, cytochrome b-5
, cytochrome b5A microsomal