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anti-Cytochrome B5 Type A (Microsomal) (CYB5A) Antibodies

The protein encoded by CYB5A is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Additionally we are shipping Cytochrome B5 Type A (Microsomal) Kits (24) and Cytochrome B5 Type A (Microsomal) Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYB5A 109672 P56395
CYB5A 1528 P00167
CYB5A 64001 P00173
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Top anti-Cytochrome B5 Type A (Microsomal) Antibodies at antibodies-online.com

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Image Western Blot analysis of CYB5A expression in transfected 293T cell line by CYB5A polyclonal antibody. A: Non-transfected lysate. B: CYB5A transfected lysate. 12% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$292.60
Details
Human Rabbit Un-conjugated IHC (p), WB CYB5A Antibody (Center)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CYB5A antibody detected the CYB5A protein (arrow). Western blot analysis of CYB5A (arrow) using rabbit polyclonal CYB5A Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CYB5A gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from A549 cells, using CYB5 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of NIH-3T3 cells, using CYB5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to CYB5A on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged CYB5A is 0.1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Rabbit Goat Un-conjugated WB   100 μL Log in to see 3 to 4 Days
$534.64
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated IHC (p), IP, ELISA, WB Anti-CYB5A / Cytochrome b5 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961212 concentration 5 ug/ml. Anti-CYB5A / Cytochrome b5 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961212 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$511.50
Details

CYB5A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Cytochrome B5 Type A (Microsomal) Antibodies

  1. Human Monoclonal CYB5A Primary Antibody for IHC (p), ELISA - ABIN514807 : Ming, Pham, Deb, Chin, Kharmate, Adomat, Beheshti, Locke, Guns: Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo. in The Journal of steroid biochemistry and molecular biology 2014 (PubMed)

More Antibodies against Cytochrome B5 Type A (Microsomal) Interaction Partners

Mouse (Murine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. Cytochrome b5 and cytokeratin 17 (show KRT17 Antibodies) are biomarkers in bronchoalveolar fluid signifying onset of acute lung injury.

Rabbit Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. the observation of weak and nonspecific interactions between CYP2B4 and cytb5 in micelles suggests that lipid bilayer structures and low curvature membrane surface are preferable for CYP2B4-cytb5 complex formation.

  2. Data suggest that the cytb5-cytP4502B4 complex structure will help unravel the mechanism by which cytb5 regulates catalysis by cytP4502B4.

  3. Two different types of cytochrome b5 orientations are present within a MFO system: the first allowing potential cytochrome b5 electron donation to P450 (show POR Antibodies), the second one inducing cytochrome b5 modulation of P450 (show POR Antibodies) structural changes.

Human Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. We conclude that cytochrome b5 can influence the electronic conductivity of cytochrome P450c17 (show CYP17A1 Antibodies) via allosteric, protein-protein interactions.

  2. Variants in CYB5A and CYB5R3 (show CYB5R3 Antibodies) should be considered in the evaluation of breast cancer risk in African American women.

  3. CYB5A is the first RA susceptibility gene involved in androgen synthesis. Our functional analysis of SNP rs1790834 indicates that it contributes to the sex bias observed in RA.

  4. both area and ratio of 3betaHSD (show HSD3B1 Antibodies) and CYB5A double positive cells, which could represent the hybrid cells of zona fasciculate and zona reticularis, are correlated with adrenal development and could influence age-related serum androstenedione levels.

  5. Two acidic residues, Glu (show DCTN1 Antibodies)-48 and Glu (show DCTN1 Antibodies)-49, of cytochrome b5 are essential for stimulating the 17,20-lyase activity of CYP17A1 (show CYP17A1 Antibodies).

  6. raises the possibility that inhibition of CYB5A-deregulated downstream pathways, such as those involving TRAF6 (show TRAF6 Antibodies), may favor autophagy-mediated cancer cell death in selected subgroups of patients

  7. CYB5A, which has a role in stearyl-CoA-desaturase activity, and RNF10 (show RNF10 Antibodies), with an unknown role in weight regulating pathways, associated with adiposity and nominally increased the risk for T2D in American Indians.

  8. Cytochrome b5 seems to play the key role in the formation of lipid-radical cycles in membranes.

  9. Results define CYB5A as a novel prognostic factor for PDAC that exerts its tumor-suppressor function through autophagy induction and TRAF6 (show TRAF6 Antibodies) modulation.

  10. CYP17A1 (show CYP17A1 Antibodies)/b5 interaction is stronger when the hydroxylase substrate pregnenolone is present in the CYP17A1 (show CYP17A1 Antibodies) active site than when the lyase substrate 17alpha-hydroxypregnenolone is in the active site.

Pig (Porcine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. Searching the porcine CYB5 gene for mutations, examine its expression, and identify genetic polymorphism in terms of androstenone levels in testis.

  2. the c.-8G>T SNP in the CYB5A gene has a significant but modest effect on boar taint in male pigs and could be useful in some breeds as part of a panel of SNP markers in a marker-assisted selection programme to produce low boar taint pigs

  3. These results demonstrate the differential effects of two forms of CYB5 on the three activities of porcine CYP17A1 (show CYP17A1 Antibodies) and show that CYB5B (show CYB5B Antibodies) does not stimulate the andien-beta synthase activity of CYP17A1 (show CYP17A1 Antibodies).

Cow (Bovine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. The study computes electron transfer rates for the [myoglobin (show MB Antibodies)(wt), cytochrome b5] complex.

  2. The solution structure of the oxidized cytochrome b(5) mutant V61H.

  3. the effects on the heme microenvironment of cytochrome b(5) caused by the mutation from Val45 to Tyr45, His45 and Glu45

  4. Results from three combined experiments demonstrate that the conserved negatively charged region of cytb5 surrounding the solvent-exposed heme edge is involved in the binding interaction with horse heart cytochrome c (show CYCS Antibodies).

  5. From a series of site-directed mutations on Cyt b5 this report assesses the contributions of amino acid residues that are expected to influence the docking and electron transfer (ET) between Cyt b5 and horse heart Cyt c (show CYCS Antibodies).

  6. simulations provided qualitative microscopic explanations of many of the differences in physical properties between outer mitochondrial membrane CYB5 isoform and microsomal CYB5 and two mutants in terms of localized changes in structure and flexibility

Horse (Equine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5).

Cytochrome B5 Type A (Microsomal) (CYB5A) Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYB5A

  • cytochrome b5 type A (microsomal) (cyb5a) antibody
  • cytochrome b-5 (Cyb5) antibody
  • cytochrome b5 (LOC100328915) antibody
  • cytochrome b5 (CYB5A) antibody
  • cytochrome b5 type A (microsomal) (CYB5A) antibody
  • cytochrome b5 type A (microsomal) (Cyb5a) antibody
  • cytochrome b5-like (LOC100735904) antibody
  • 0610009N12Rik antibody
  • Cyb5 antibody
  • CYB5A antibody
  • MCB5 antibody
  • MGC80327 antibody
  • wu:fb44a11 antibody
  • zgc:64123 antibody

Protein level used designations for CYB5A

cytochrome b5 , cytochrome b5 type A (microsomal) , type 1 cyt-b5 , cytochrome b-5 , cytochrome b5A microsomal

GENE ID SPECIES
406409 Danio rerio
446542 Xenopus laevis
548733 Xenopus (Silurana) tropicalis
109672 Mus musculus
100328915 Oryctolagus cuniculus
100861011 Capra hircus
1528 Homo sapiens
64001 Rattus norvegicus
476167 Canis lupus familiaris
414799 Sus scrofa
281110 Bos taurus
100335454 Bos taurus
414798 Gallus gallus
100052210 Equus caballus
100307037 Ovis aries
100735904 Cavia porcellus
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