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COA3 encodes a member of the cytochrome c oxidase assembly factor family. Additionally we are shipping Cytochrome C Oxidase Assembly Factor 3 Kits (20) and Cytochrome C Oxidase Assembly Factor 3 Antibodies (19) and many more products for this protein.
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COX14 was undetectable in COA3 subject fibroblasts, and that COA3 was undetectable in fibroblasts from a COX14 subject, demonstrating the interdependence of these two COX (show COX8A Proteins) assembly factors
Data show that mitochondrial protein (show COX6B2 Proteins) ccdc56/MITRAC12/COA3 positively regulates mitochondrial fission by recruiting the fission factor Drp1 (show CRMP1 Proteins).
hCOA3 stabilizes COX1 co-translationally and promotes its assembly with COX (show COX8A Proteins) partner subunits.
Study comprehensively identified mammalian cytochrome c (show CYCS Proteins) oxidase assembly factors. These analyses led to the discoveryof MITRAC12, which defines the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c (show CYCS Proteins) oxidase)complexes.
Human ortholog of fungal COA3 (Cytochrome oxidase assembly)
This gene encodes a member of the cytochrome c oxidase assembly factor family. Studies of a related gene in fly suggest that the encoded protein is localized to mitochondria and is essential for cytochrome c oxidase function.
coiled-coil domain-containing protein 56
, cytochrome C oxidase assembly factor 3 homolog, mitochondrial
, cytochrome c oxidase assembly protein 3 homolog, mitochondrial
, coiled-coil domain containing 56
, mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa