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Cytochrome C Oxidase Assembly Homolog 10 (Yeast) Proteins (COX10)

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. Additionally we are shipping COX10 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat COX10 COX10 363617  
COX10 1352 Q12887
Mouse COX10 COX10 70383 Q8CFY5
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Top COX10 Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

COX10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

More Proteins for Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) Interaction Partners

Human Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) interaction partners

  1. On the basis of its pivotal role in regulating cell death upon COX (show COX8A Proteins) dysfunction, CerS6 (show CERS6 Proteins) might potentially represent a novel target for therapeutic intervention in mitochondrial diseases caused by COX (show COX8A Proteins) dysfunction.

  2. ISCU (show ISCU Proteins) and COX10 are target genes of miR (show MLXIP Proteins)-210 related to mitochondrial metabolism

  3. COX 15 mRNA was significantly more abundant in the cerebral tissue of Alzheimer's disease (AD) patients and COX10 and COX15 SNP were significantly less represented in the patient group, suggesting a possible protective role toward the risk for AD

  4. The expression of the AOX (show ACOX1 Proteins), well-tolerated by the cells, compensates for both the growth defect and the pronounced oxidant-sensitivity of COX (show COX8A Proteins)-deficient human cells.

  5. Cytochrome c (show CYCS Proteins) oxidase is decreased significantly in platelets and hippocampus in Alzheimer patients compared to controls.

  6. COX10 has a role in mitochondrial heme A biosynthesis

  7. This study report a cytochrome c (show CYCS Proteins) oxidase (COX (show COX8A Proteins))-deficient patient, clinically affected with Leigh-like disease, with a homozygous mutation in the COX10 start codon.

  8. Geranylgeranyltransferase inhibitor-2147 (GGTI (show PGGT1B Proteins)-2147), an inhibitor of this enzyme prenylation, elicited significant inhibition of glucose-stimulated insulin (show INS Proteins) secretion from INS (show INS Proteins) 832/13 islet cells.

Mouse (Murine) Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) interaction partners

  1. Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c (show CYCS Proteins) oxidase deficiency.

  2. The levels of respiratory complex I were markedly reduced in COX10 knockout clones.

Arabidopsis thaliana Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) interaction partners

COX10 Protein Profile

Protein Summary

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.

Gene names and symbols associated with COX10

  • COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (COX10)
  • COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (Cox10)
  • cytochrome c oxidase assembly homolog 10 (cox10)
  • cytochrome c oxidase assembly homolog 10 (yeast) (cox10)
  • cytochrome c oxidase assembly homolog 10 (yeast) (COX10)
  • cytochrome c oxidase assembly protein 10 (Cox10)
  • protoheme IX farnesyltransferase (COX10)
  • 2410004F01Rik protein
  • AU042636 protein
  • cytochrome c oxidase 10 protein
  • F4I1.50 protein
  • F4I1_50 protein
  • im:7145568 protein
  • im:7157205 protein
  • wu:fb18a03 protein

Protein level used designations for COX10

protoheme IX farnesyltransferase, mitochondrial , heme A:farnesyltransferase , COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase , cytochrome c oxidase assembly protein , cytochrome c oxidase subunit X , heme A: farnesyltransferase , heme O synthase

GENE ID SPECIES
417329 Gallus gallus
489515 Canis lupus familiaris
511440 Bos taurus
363617 Rattus norvegicus
779326 Xenopus laevis
553384 Danio rerio
1352 Homo sapiens
70383 Mus musculus
819059 Arabidopsis thaliana
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