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anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) Antibodies

CYP19A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Kits (48) and Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP19A1 1588 P11511
CYP19A1 25147  
CYP19A1 13075 P28649
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Top anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Baboon Mouse Un-conjugated IF, IHC (p), WB Western blot analysis of human placenta extract probed with antiI Hu Cytochrome P450 Aromatase (ABIN120192) followed by F(ab')2 Rabbit anti Mouse IgG:HRP (ABIN121365). 1 mL Log in to see 6 to 8 Days
$929.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB AP14221PU-N CYP19A1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human placenta tissue using peroxidase-conjugate and DAB chromogen. Western blot analysis using AP14221PU-N CYP19A1 antibody in Jurkat cell line lysates (35 µg/lane). CYP19A1 (arrow) was detected using the purified antibody at 1/60 dilution. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-CYP19A1(Center) Pab (ABIN391456) in HL60 cell line lysates (35 µg/lane). CYP19A1(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB AP14030PU-N CYP19A1 antibody staining of HL60 cell line lysates by Western blot (35 µg/lane). CYP19A1 (arrow) was detected using the purified antibody at 1/60 dilution. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated IHC, WB Western blot analysis of Aromatase in human brain cell lysate. 100 μg Log in to see 2 to 3 Days
$346.50
Details
Human Goat Un-conjugated ELISA, WB ABIN238672 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Baboon Mouse Un-conjugated IF, IHC (p), WB   50 μL Log in to see 6 to 8 Days
$159.50
Details
Baboon Mouse Un-conjugated IHC (p), WB   0.2 mL Log in to see 6 to 8 Days
$335.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$478.50
Details

CYP19A1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Antibodies

  1. Baboon Monoclonal CYP19A1 Primary Antibody for IF, IHC (p) - ABIN120192 : Colette, Lousse, Defrère, Curaba, Heilier, Van Langendonckt, Mestdagt, Foidart, Loumaye, Donnez: Absence of aromatase protein and mRNA expression in endometriosis. in Human reproduction (Oxford, England) 2009 (PubMed)
    Show all 16 references for ABIN120192

  2. Baboon Monoclonal CYP19A1 Primary Antibody for IHC (p), WB - ABIN488153 : Bender, Zhou, Wilkars, Fester, Lanowski, Paysen, König, Rune: Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. in Cerebral cortex (New York, N.Y. : 1991) 2010 (PubMed)
    Show all 16 references for ABIN488153

  3. Baboon Monoclonal CYP19A1 Primary Antibody for IF, IHC (p) - ABIN488154 : Horling, Santos, Fischer: The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN. in Molecular human reproduction 2011 (PubMed)
    Show all 15 references for ABIN488154

  4. Chicken Polyclonal CYP19A1 Primary Antibody for IHC, WB - ABIN223293 : Bukulmez, Hardy, Carr, Word, Mendelson: Inflammatory status influences aromatase and steroid receptor expression in endometriosis. in Endocrinology 2008 (PubMed)
    Show all 5 references for ABIN223293

  5. Human Polyclonal CYP19A1 Primary Antibody for EIA, WB - ABIN359546 : Ikeda, Sasazuki, Natsukawa, Shaura, Koizumi, Kasuga, Ohnami, Sakamoto, Yoshida, Iwasaki, Tsugane: Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. in The American journal of gastroenterology 2008 (PubMed)
    Show all 2 references for ABIN359546

  6. Human Polyclonal CYP19A1 Primary Antibody for EIA, IHC (p) - ABIN359737 : Xita, Georgiou, Lazaros, Psofaki, Kolios, Tsatsoulis: The synergistic effect of sex hormone-binding globulin and aromatase genes on polycystic ovary syndrome phenotype. in European journal of endocrinology / European Federation of Endocrine Societies 2008 (PubMed)
    Show all 2 references for ABIN359737

  7. Human Polyclonal CYP19A1 Primary Antibody for IHC (p), WB - ABIN374919 : Van Poznak, Hayes: Aromatase inhibitors for the treatment of breast cancer: is tamoxifen of historical interest only? in Journal of the National Cancer Institute 2006 (PubMed)

More Antibodies against Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Interaction Partners

Pig (Porcine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. P450arom was expressed in all layers of the arterial and venous vessels of the spermatic cord with higher intensity of staining in June long daylight) compared to December(short daylight).

  2. Decreased estradiol production via suppression of aromatase may be one of the mechanisms by which miR (show MYLIP Antibodies)-378 regulates the maturation of cumulus-oocyte complexes.

  3. show that micro-RNA378 (miR (show MYLIP Antibodies)-378) is spatiotemporally expressed in porcine granulosa cells, the cells that generate estradiol in the ovary during follicular development, in an inverse manner compared with the expression of aromatase

  4. Pig ejaculated spermatozoa express aromatase.

  5. The presence of aromatase and 11beta-HSD 2 (show HSD11B2 Antibodies) in Leydig cells increased, together with germ and Sertoli cell numbers.

  6. This study demonstrates that transferrin (show Tf Antibodies) had a dose-dependent inhibitory effect on follicle stimulating hormone-stimulated aromatase activity.

Human Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. EGb 761 reduced the tumor size and significantly reduced tumor CYP19 mRNA expression.

  2. The CT genotype of the rs2289105 polymorphism in the CYP19 gene is associated with a decreased risk of CHD (show CHDH Antibodies) and may be a genetic marker of protection from CHD (show CHDH Antibodies)

  3. Metformin inhibits PGE2-induced CYP19A1 mRNA expression/aromatase activity via AMPK (show PRKAA1 Antibodies) activation in endometriotic stromal cells.

  4. Higher CYP19A1 expression and E2 concentrations are associated with increased risk of endometrial cancer.

  5. study to determine distribution of CYP19(TTTA)n polymorphism in Mexican general population and search for associations of particular genotypes with hip fracture and lumbar spine osteoporosis; the A1 allele and the A1A1 genotype were associated with an elevated risk of fracture; the A2 allele was associated with protection of hip fracture as the A2A2 genotype

  6. The leptin (show LEP Antibodies), ObR (show LEPR Antibodies) and aromatase protein expression levels were increased in lesions in the vaginal septum and were decreased in the intestine lesions

  7. The CYP19A1 rs10046 polymorphism is associated with cardiovascular risk factors such as circulating apoB (show APOB Antibodies), insulin (show INS Antibodies) resistance and hypertension in a sex- and obesity-specific manner.

  8. The rs6493497 and rs7176005 SNPs of the CYP19A1 gene may be genetic markers that influence the risk of FPHL in this Chinese population.

  9. the relationship between CYP19 gene polymorphisms and breast cancer in Xinjiang Uigur women was investigated.

  10. Our findings suggested that CYP19A1 and HSD17B2 (show HSD17B2 Antibodies) polymorphisms might be associated with circulating sex hormone levels in Japanese postmenopausal women, independent of current BMI.

Cow (Bovine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. in granulosa cells of dominant follicles the concentration of CYP19P1 mRNA was very low compared to CYP19A1 mRNA. CONCLUSIONS: CYP19P1 and CYP19A1 transcripts might interfere in placental cotyledons

  2. These data suggest that a major reason why CYP19A1 is not expressed in luteinized cells (and the corpus luteum) of ruminants may be the stimulatory effect of FOXL2 (show FOXL2 Antibodies), which does not appear to be the case in the human and rat.

  3. This study evaluated the relationships among aromatase, IGF-1 (show IGF1 Antibodies), IGF2R (show IGF2R Antibodies), and FSH (show BRD2 Antibodies) levels expressed in ovarian follicles of cattle selected for twin pregnancies.

  4. Data indicated de novo DNA methylation (show HELLS Antibodies) fter the luteinizing hormone-induced down-regulation of CYP19A1 expression, suggesting that DNA methylation (show HELLS Antibodies) might play a role for permanent silencing of previously down-regulated genes.

  5. P450(AROM) is localized in the cytoplasm and only seldom present in the fine extensions of the cells in frontal cortex.

  6. Granulosa and theca of well-characterized large bovine follicles were isolated before and after the LH surge. CYP19A1, HSD3B1 (show HSD3B1 Antibodies), and CYP17A1 (show CYP17A1 Antibodies) transcripts were quantified by real-time PCR (qPCR) and the chromatin condensation was determined.

  7. DNA methylation (show HELLS Antibodies) may have a role in the permanent shutdown of promoter 2-directed cytochrome P450 19A1(CYP19A1) expression in large (granulosa derived) lutein cells

  8. fetal ovary of cattle has the steroidogenic enzyme aromatase to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary

  9. granulosa cell clustering is accompanied by marked increases in FSHr (show FSHR Antibodies), IGF-1r (show IGF1R Antibodies), and p450 arom expression, and precedes induction and subsequent peak E2 production

  10. demonstrates that cattle and sheep use different promoters to direct aromatase(Cyp19) expression during pregnancy

Mouse (Murine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. Findings indicate that sex chromosome factors determine sex differences in aromatase expression in the stria terminalis and in the anterior amygdaloid area of mouse embryos.

  2. CELF1 (show CELF1 Antibodies) downregulates Cyp19a1 (Aromatase) posttranscriptionally to achieve high concentrations of testosterone compatible with spermiogenesis completion.

  3. Aromatase plays an important role in the survival of metastatic ERalpha (show ESR1 Antibodies) breast cancer cells by suppressing anoikis.

  4. aromatase may play a key role in the pathogenesis of Sjogren syndrome-like lesions by controlling the target organ and adipose tissue-associated macrophage; increased MPC1 (show BRP44L Antibodies) protein expression has a role in adiposity

  5. The protective effect of female gender on abdominal aortic aneurysms is due to estrogen synthesis and requires the presence of both ovarian and extragonadal/peripheral aromatase.

  6. Aromatase signaling is common in the mouse brain; locally synthesized brain estrogens could mediate biological effects by activating pre- and post-synaptic estrogen alpha and beta receptors, and androgen receptors.

  7. Male Aromatase knockout mice develop hepatic glucose intolerance.

  8. Cerebrovascular endothelial aromatase plays an important and sexually dimorphic role in cerebrovascular function and that aromatase inhibitors in clinical use may have cardiovascular consequences in both males and females.

  9. CYP19A1 gene is driven by promoters PII, I.4, and I.3 in the seminal vesicles, and by promoters PII and I.4 in the urinary bladder.

  10. Lhx2 (show LHX2 Antibodies) is involved in the transcriptional regulation of aromatase in the rodent brain.

Horse (Equine) Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. co-localization of estrogen receotirs with aromatase in horse trophoblast suggests auto- or intracrine functions of oestrogens in this cell type

Goat Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. These data suggest that a major reason why CYP19A1 is not expressed in luteinized cells (and the corpus luteum) of ruminants may be the stimulatory effect of FOXL2 (show FOXL2 Antibodies), which does not appear to be the case in the human and rat.

  2. Relative mRNA expression for insulin (show INS Antibodies) and FSH (show BRD2 Antibodies) receptors and cytochrome P450 aromatase in cultured follicles.

Xenopus laevis Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) interaction partners

  1. We found that cyp19a1 expression is highly regionalized in the brains of both sexes.

  2. Cyp19a1 expression leads to female sex determination in Xenopus laevis.

  3. brain-specific (show CALY Antibodies) promoter/exon I.f of the cyp19a1 has cis (show CISH Antibodies)-elements for several transcriptional factors

  4. binding sequences to a specific trans-activating factor upstream of the p450 (show POR Antibodies) aromatase promoter II

  5. The ontogenetic patterns of Aro, Srd5a1 (show SRD5A1 Antibodies) and Srd5a2 (show SRD5A2 Antibodies) suggest that these genes are involved in sexual differentiation of gonads and brain already in early developmental stages.

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity\; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.

Gene names and symbols associated with CYP19A1

  • aromatase (SAV_2383) antibody
  • cytochrome P450 aromatase (pfcyp19b-tstr) antibody
  • cytochrome P450 19A1 (CYP19A1) antibody
  • cytochrome P450 19A3 (CYP19A3) antibody
  • cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP19A1) antibody
  • cytochrome P450, family 19 (CYP19) antibody
  • cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1) antibody
  • cytochrome P450, family 19, subfamily a, polypeptide 1 (Cyp19a1) antibody
  • cytochrome P450, family 19, subfamily A, polypeptide 1 (cyp19a1) antibody
  • Ar antibody
  • ArKO antibody
  • aro antibody
  • ARO1 antibody
  • Aromatase antibody
  • CPV1 antibody
  • CYAR antibody
  • cyp19 antibody
  • cyp19a antibody
  • CYP19A1 antibody
  • CYP19P1 antibody
  • CYPXIX antibody
  • Int-5 antibody
  • Int5 antibody
  • P-450AROM antibody
  • P450 arom antibody
  • P450AROM antibody
  • p450arom-A antibody

Protein level used designations for CYP19A1

aromatase , cytochrome P450 aromatase , CYPXIXA1 , cytochrome P-450AROM , cytochrome P450 19 type I , cytochrome P450, family19, subfamily A, polypeptide 1 , estrogen synthase , CYPXIXA3 , aromatase cytochrome P450 , cytochrome P450 19 type III , cytochrome P450, family 19, subfamily A, polypeptide 3 , type I cytochrome p450 aromatase , CYPXIX , cytochrome P450 19A1 , estrogen synthetase , cytochrome P450, subfamily XIX (aromatization of androgens) , flavoprotein-linked monooxygenase , microsomal monooxygenase , Cytochrome P450, 19, aromatase , P-450AROM , cytochrome P450 family 19 subfamily a , cytochrome P450, subfamily 19 , cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase , cytochrome P450, 19, aromatase , cytochrome P450 17-alpha , Cytochrome P-450AROM , Cytochrome P450 19A1 , Estrogen synthase , p450 aromatase A

GENE ID SPECIES
1213743 Streptomyces avermitilis MA-4680
100379639 Takifugu rubripes
403331 Sus scrofa
403333 Sus scrofa
494003 Canis lupus familiaris
100144423 Ovis aries
414854 Gallus gallus
1588 Homo sapiens
25147 Rattus norvegicus
281740 Bos taurus
13075 Mus musculus
100009712 Equus caballus
100328545 Oryctolagus cuniculus
100861413 Capra hircus
373656 Xenopus laevis
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