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Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 Proteins (CYP2J2)

CYP2J2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2J2 Antibodies (68) and CYP2J2 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CYP2J2 CYP2J2 502969  
CYP2J2 1573 P51589
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Top CYP2J2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP2J2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) interaction partners

  1. Data suggest that antiarrhythmic prodrugs amiodarone and dronedarone are extensively metabolized by CYP2J2; specific CYP2J2 metabolites include N-desbutyldronedarone and N-desethylamiodarone, potent [reversible/irreversible] inhibitors of CYP2J2.

  2. Tanshinone IIA exerts its anticancer effect by inhibiting CYP2J2 activity in HepG2 cells.

  3. CYP2J2 expression showed significant upregulation (P<0.05) during Cy treatment before stem cell transplantation

  4. Here we present the detection of substrate binding to cytochrome P450-2J2 (CYP2J2), the predominant P450 (show CYP2B6 Proteins) in the human heart, using a combination of Nanodisc technology and a nanohole plasmonic sensor

  5. Our results suggest that individuals with any conventional risk factor for MI along with CYP2J2*7 variant allele may be predisposed to risk of myocardial infarct in South Indian population

  6. CYP2J2 and EETs prevent cardiac fibrosis and cardiac dysfunction by suppressing transmission of pro-inflammation from cardiomyocytes to macrophages in heart

  7. findings can give a structural mechanism for the mutation-induced dysfunction in the CYP2J2-mediated arachidonic acid metabolism.

  8. The CYP2J2 rs890293 T allele and GT+TT genotype were significantly associated with an increased risk of late onset Alzheimer disease.

  9. The present study shows that elevated EET levels in BC tissues are associated with upregulation of CYP2C8, 2C9, and 2J2, and downregulation of sEH, and are also associated with aggressive cell behavior in BC patients.

  10. Data suggest that up-regulation of CYP2J2 activity can attenuate type 2 diabetes and improve insulin (show INS Proteins) resistance via down-regulation of NFkappaB (show NFKB1 Proteins) and MAPK (show MAPK1 Proteins) signaling pathways and up-regulation of PPARgamma (show PPARG Proteins).

CYP2J2 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.

Gene names and symbols associated with CYP2J2

  • cytochrome P450, family 2, subfamily j, polypeptide 16 (Cyp2j16)
  • cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2)
  • hypothetical LOC530929 (CYP2J2)
  • cytochrome P450, family 2, subfamily J, polypeptide 2 (cyp2j2)
  • cytochrome P450, family 2, subfamily j, polypeptide 4 (Cyp2j4)
  • CPJ2 protein
  • CYP2J2 protein
  • MGC134319 protein
  • RGD1561242 protein

Protein level used designations for CYP2J2

cytochrome P450, family 2, subfamily J, polypeptide 2 , hypothetical LOC530929 , cytochrome P450, family 2, subfamily J-like , CYPIIJ2 , arachidonic acid epoxygenase , cytochrome P450 2J2 , cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2 , flavoprotein-linked monooxygenase , microsomal monooxygenase

GENE ID SPECIES
502969 Rattus norvegicus
424678 Gallus gallus
521656 Bos taurus
530929 Bos taurus
100158388 Xenopus laevis
1573 Homo sapiens
65210 Rattus norvegicus
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