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CYP2W1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 Kits (7) and Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 Proteins (4) and many more products for this protein.
Showing 10 out of 41 products:
Human Polyclonal CYP2W1 Primary Antibody for EIA, IHC (p) - ABIN360102
Gomez, Karlgren, Edler, Bernal, Mkrtchian, Ingelman-Sundberg: Expression of CYP2W1 in colon tumors: regulation by gene methylation. in Pharmacogenomics 2007
Show all 3 references for ABIN360102
Data suggest that canonical cytochrome P-450 (show CYP Antibodies) reductants (cytochrome P450 reductase (show POR Antibodies); cytochrome b5 (show CYB5A Antibodies)) cannot serve as electron donors for CYP2W1, a colon tumor-specific enzyme; glycosylation of CYP2W1 at Asn177 is required for full catalytic activity.
Results show the developmental expression of CYP2W1 in the GI tract mediated by epigenetic modifications, its specific location, and regulation by anticancer drugs which can be considered as an adjuvant therapy of colon and hepatic cancers.
Low KRT13 (show KRT13 Antibodies) mRNA expression is associated with oral squamous cell carcinoma.
CYP2W1 is highly expressed in both normal and neoplastic adrenal glands making it a promising tool for targeted therapy in ACC
High CYP2W1 expression is seen in 26% of primary colorectal tumors and in 48% of corresponding liver metastases.
CYP2W1 could play an important role in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and might serve as a valuable prognostic marker and potential target for gene therapy in the treatment of HCC (show FAM126A Antibodies).
No significant differences in the distribution of CYP2W1*1, CYP2W1*2 and CYP2W1*6 alleles were found between CRC (show CALR Antibodies) patients and controls.
Results of the current study were in agreement with those of the previous pilot study and show that higher expression of CYP2W1 seems to be of prognostic value in colon cancer.
study did not detect an association between the CYP2W1, 4F11 and 8A1 genes polymorphisms and breast cancer risk in a Mexican population; however, some clinico-pathological risk factors interact with CYP2W1 genotypes and modifies susceptibility to breast cancer
a role for human cytochrome P450 2W1 in selective oxidation of lysophospholipids
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
cytochrome P450, family 2, subfamily W, polypeptide 1
, cytochrome P450 2W1