Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
CYP3A4 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP3A4 Kits (35) and CYP3A4 Proteins (6) and many more products for this protein.
Showing 10 out of 115 products:
Human Polyclonal CYP3A4 Primary Antibody for EIA, WB - ABIN360097
Nelson, Zeldin, Hoffman, Maltais, Wain, Nebert: Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. in Pharmacogenetics 2004
Show all 3 references for ABIN360097
Human Monoclonal CYP3A4 Primary Antibody for ICC, FACS - ABIN969512
van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. in Drug metabolism and disposition: the biological fate of chemicals 2009
Show all 2 references for ABIN969512
Human Polyclonal CYP3A4 Primary Antibody for IHC, ELISA - ABIN1450923
Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003
Show all 2 references for ABIN1450923
Human Polyclonal CYP3A4 Primary Antibody for IP, WB - ABIN947776
Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. in Pharmacology research & perspectives 2014
Human Polyclonal CYP3A4 Primary Antibody for WB - ABIN2784528
Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. in Clinical pharmacology and therapeutics 2014
It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5 (show CYB5A Antibodies)).
study of genetic variants of CYP3A4 in cynomolgus and rhesus macaques from China
Both donor and recipient CYP3A5 (show CYP3A5 Antibodies) genotype significantly influences tacrolimus once daily pharmacokinetics in stable liver transplant recipients, while CYP3A4*22 is not a suitable biomarker
Data provides evidence that CYP3A4*22 (rs35599367) increases the formation of the nonfunctional CYP3A4 splice variant with partial intron 6 retention, thereby reducing the production of functional full-length CYP3A4 mRNA.
Early postpartum women possessed higher CYP3A activity based on plasma 4beta-hydroxycholesterol and had a large pharmacokinetic variability in amlodipine disposition.
patients who expressed CYP3A5 (show CYP3A5 Antibodies)*3 had an increased incidence of vincristine-related neurotoxicity.
Report CYP3A4 induction in six fully characterized cryopreserved human hepatocyte preparations and HepaRG cell line.
The shape and localization of human CYP3A4 protein embedded in a phospholipid nanodisc environment has been determined.
a critical role of the CYP3A5 (show CYP3A5 Antibodies) 6986A>G and CYP3A4 -392A>G polymorphisms on the variation of Tac (show IL2RA Antibodies) exposure during the early and the late post-transplant phase, respectively.
CYP3A4-expressing recombinant human liver microsomal preparation showed significantly higher Km for the formation of 1'-hydroxymidazolam than baculovirus-infected insect cell microsomes.
CYP3A4 further activates, rather than inactivates, 20-hydroxy vitamin D3.
In this cohort study in morbidly obese patients, systemic clearance of midazolam was 1.7 times higher 1 year after bariatric surgery, which may potentially result from an increase in hepatic CYP3A activity per unit of liver weight.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
cytochrome P450 3A4
, cytochrome P450, family 3, subfamily A, polypeptide 4
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4
, Cytochrome P450 CM3A-10
, cytochrome P450 3A21
, 1,8-cineole 2-exo-monooxygenase
, P450-III, steroid inducible
, albendazole monooxygenase
, albendazole sulfoxidase
, cytochrome P450 3A3
, cytochrome P450 HLp
, cytochrome P450 NF-25
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3
, cytochrome P450-PCN1
, glucocorticoid-inducible P450
, nifedipine oxidase
, quinine 3-monooxygenase
, taurochenodeoxycholate 6-alpha-hydroxylase
, cytochrome P450 CYP3A12
, cytochrome P450 3A80