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anti-Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) Antibodies

CYP7A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP7A1 Kits (50) and CYP7A1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP7A1 1581 P22680
CYP7A1 13122 Q64505
CYP7A1 25428 P18125
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Top anti-CYP7A1 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse liver lysates probed with Anti-CYP7A1 Polyclonal Antibody, Unconjugated (ABIN739725) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 90min in 37˚C 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of CYP7A1 Antibody (C-term) (ABIN392530) in K562, HepG2 cell line lysates (35 µg/lane). CYP7A1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CYP7A1 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: 293T Cell Lysate Lane 3: JURKAT Cell Lysate Anti-CYP7A1 antibody, IHC(P) IHC(P): Human Liver Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Mouse Rabbit Un-conjugated WB Observed bind size: 58KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

CYP7A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CYP7A1 Antibodies

  1. Human Polyclonal CYP7A1 Primary Antibody for IF (p), IHC (p) - ABIN739725 : Gabbi, Bertolotti, Anzivino, Macchioni, Del Puppo, Ricchi, Carubbi, Tagliafico, Romagnoli, Odoardi, Loria, Losi, Carulli: Effects of bile duct ligation and cholic acid treatment on fatty liver in two rat models of non-alcoholic fatty liver disease. in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2012 (PubMed)
    Show all 4 references for ABIN739725

  2. Human Polyclonal CYP7A1 Primary Antibody for EIA, WB - ABIN360417 : Lenícek, Komárek, Zimolová, Kovár, Jirsa, Lukás, Vítek: CYP7A1 promoter polymorphism -203A>C affects bile salt synthesis rate in patients after ileal resection. in Journal of lipid research 2008 (PubMed)
    Show all 2 references for ABIN360417

More Antibodies against CYP7A1 Interaction Partners

Human Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) interaction partners

  1. Macrophage cholesterol efflux in patients with type II diabetes mellitus was significantly reduced, and that this reduction was associated with the down-regulation of CYP7A1 expression.

  2. CYP7A1 and APOE (show APOE Antibodies) isoform are associated with the extent of reduction in circulating LDL cholesterol in response to plant sterols consumption.

  3. The CYP7A1 rs7833904 polymorphism may modify the risk of CAD (show CAD Antibodies).

  4. The CYP7A1 crystallographic models identify residues involved in cholest-4-en-3 (show EN1 Antibodies)-one binding.

  5. we identified for the first time a significant association of the A-204C polymorphism of the CYP7A1 gene and development of tuberculosis in a Moroccan population

  6. The CYP7A1 -204A>C polymorphism is significantly associated with serum lipid levels in Asian population, but not gallbladder stone disease. [Meta-analysis]

  7. Cyp7a1 is a direct Thyroid hormone receptor (show THRA Antibodies) (TR) target gene that responds to physiologic TR levels through a set of distinct response elements in its promoter.

  8. Activation of the VDR (show CYP27B1 Antibodies) represses hepatic SHP (show LAMC1 Antibodies) to increase levels of CYP7A1 and reduce cholesterol.

  9. Two known single nucleotide polymorphisms were identified in the 5'-UTR (show UTS2R Antibodies) of CYP7A1 and both were associated with neuromyelitis optica but not with Multiple sclerosis.

  10. Genetic variants of CYP7A1 and its transcriptional activators (HNF4A (show HNF4A Antibodies) and PPARGC1A (show PPARGC1A Antibodies)) may activate bile acid synthesis, resulting in the accumulation of bile acids in hepatocytes leading primary biliary cirrhosis progression.

Mouse (Murine) Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) interaction partners

  1. Mice deficient in cholesterol 7 alpha-hydroxylase, supplemented with chenodeoxycholic acid, have altered liver and intestinal bile acids.

  2. Activation of the VDR (show CYP27B1 Antibodies) represses hepatic SHP (show LAMC1 Antibodies) to increase levels of CYP7A1 and reduce cholesterol.

  3. Cholesterol lowering properties of oats involve increased production of bile acids via the classic pathway with up-regulation of CYP7A1 and CYP8B1 (show CYP8B1 Antibodies).

  4. A CYP7A1/SREBP2 (show SREBF2 Antibodies)/miR (show MLXIP Antibodies)-33a axis plays a critical role in regulation of hepatic cholesterol, bile acid, and fatty acid synthesis.

  5. Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt (show SLC10A2 Antibodies)(-/-)apoE (show APOE Antibodies)(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1).

  6. HNF4alpha (show HNF4A Antibodies) and LRH-1 (show NR5A2 Antibodies) promote active transcription histone marks on the Cyp7a1 promoter that are reversed by FGF19 (show FGF19 Antibodies) in a SHP (show LAMC1 Antibodies)-dependent manner

  7. these data suggest that FGF7 (show FGF7 Antibodies) is a novel regulator of CYP7A1 expression in hepatocytes and may prevent hepatocytes from accumulating toxic bile acids during liver injury and fibrosis.

  8. Results indicate that although PPARgamma (show PPARG Antibodies) activation increased PCSK9 (show PCSK9 Antibodies) expression, PPARgamma (show PPARG Antibodies) activation induced LDLR (show LDLR Antibodies) and CYP7A1 expression that enhanced LDL cholesterol metabolism.

  9. Cyanidin-3-O-beta-glucoside consumption reduced hypercholesterolemia, promoted fecal bile acid excretion and upregulated hepatic cholesterol 7a-hydroxylase expression (CYP7A1).

  10. Chitosan oligosaccharides promote reverse cholesterol transport and expression of scavenger receptor BI and CYP7A1 in mice

Pig (Porcine) Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1) interaction partners

  1. the effect of polymorphism in the cholesterol 7-alpha hydroxylase gene locus and dietary cholesterol on cerebrum cholesterol in neonatal pigs fed sow's milk formulas are reported.

CYP7A1 Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.

Gene names and symbols associated with CYP7A1

  • cholesterol 7-alpha-hydroxylase (Cyp7a1) antibody
  • cytochrome P450, family 7, subfamily A, polypeptide 1 (CYP7A1) antibody
  • cytochrome P450, family 7, subfamily a, polypeptide 1 (Cyp7a1) antibody
  • CHAP antibody
  • CP7A antibody
  • CYP7 antibody
  • CYP7S1 antibody
  • CYPVII antibody

Protein level used designations for CYP7A1

cholesterol 7-alpha-hydroxylase , cholesterol 7-alpha-monooxygenase , cytochrome P450 7A1 , cytochrome P450, subfamily VIIA polypeptide 1 , CYPVII , cholesterol 7 alpha hydroxylase , cytochrome P450, 7a1 , cholesterol 7-alpha hydroxylase , cytochrome P450 (cholesterol hydroxylase 7 alpha) , cholesterol 7alpha-hydroxylase , cholesterol 7 alpha-hydroxylase

GENE ID SPECIES
100337633 Cavia porcellus
1581 Homo sapiens
13122 Mus musculus
25428 Rattus norvegicus
448985 Sus scrofa
100328551 Oryctolagus cuniculus
414834 Gallus gallus
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