Cytoglobin Proteins (CYGB)

CYGB encodes a globin protein found in vertebrate cells. Additionally we are shipping Cytoglobin Antibodies (60) and Cytoglobin Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYGB 114886 Q9CX80
CYGB 114757 Q8WWM9
CYGB 170520 Q921A4
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Top Cytoglobin Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$407.00
Details
Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$385.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
$225.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,454.83
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$467.86
Details

CYGB Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, , , ,
Rat (Rattus) ,
,

More Proteins for Cytoglobin (CYGB) Interaction Partners

Zebrafish Cytoglobin (CYGB) interaction partners

  1. The results uncover unexpected properties of zebrafish cytoglobin 1 and reveal the pivotal role of cytoglobin 1 in the transition of heme cytoglobin 1 from six-coordinate to five-coordinate oxygen carriers and nitrite reductases.

Mouse (Murine) Cytoglobin (CYGB) interaction partners

  1. Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF being an upstream regulator.

  2. Cygb, expressed in hepatic stellate cells during liver fibrosis, plays role in cancer development with nonalcoholic steatohepatitis.

  3. Studied hepatic stellate cell cytoglobin involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1 (show CYP2E1 Proteins).

  4. cytoglobin serves an important role in muscle repair and regeneration

  5. Cygb deficiency induces susceptibility to cancer development in the liver and lungs of mice exposed to N,N-diethylnitrosamine

  6. The anatomical data indicate a role in NO signalling for cytoglobin and involvement in sleep-wake cycling for cytoglobin and neuroglobin (show NGB Proteins)

  7. The nuclear localization of cytoglobin opens new perspectives for possible function(s) of globin-folded proteins as transcriptional regulators.

  8. differential expression of cytoglobin argues against a general respiratory function of this molecule, but rather indicates a connective tissue-specific function

  9. cytoglobin is significantly upregulated upon hypoxia and this is dependent on the tissue and severity of hypoxia

  10. In the neuronal retina, cytoglobin is expressed in a subset of neurons of the ganglion cell and inner nuclear layers. Cytoglobin is also present in the inner plexiform layer, but absent from the pigment cells.

Human Cytoglobin (CYGB) interaction partners

  1. the study reveals a novel mechanism for the regulated expression of Cygb and also assigns a new role to Cygb in cell cycle control.

  2. Data suggest that cytochrome b5 (CYB5 (show CYB5A Proteins)) and cytochrome b5 reductase 3 (CYB5R3 (show CYB5R3 Proteins)) can reduce human cytoglobin (CYGB) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin (show HBB Proteins) and myoglobin (show MB Proteins); the three proteins (CYB5 (show CYB5A Proteins)+CYB5R3 (show CYB5R3 Proteins)+CYGB) appear to constitute a metabolon involved in generation of nitric oxide.

  3. DeltaNp63-CYGB axis is also present in lung and breast cancer cell lines, indicating that CYGB-mediated ROS (show ROS1 Proteins)-scavenging activity may also have a role in epithelial tumours

  4. Propose a bipartite lipid binding model that rationalizes the modes of interactions of cytoglobin with phospholipids, the effects on structural re-arrangements and the peroxidase activity of the hemoprotein.

  5. This review provides an overview of the proposed role of cytoglobin and explores its potential functional role as a biomarker for cancer and other diseases

  6. Cygb, expressed in hepatic stellate cells during liver fibrosis, plays role in cancer development with nonalcoholic steatohepatitis.

  7. Cygb stabilizes p53 (show TP53 Proteins) by inhibiting its ubiquitination and elicit cell cycle arrest in DNA damaged cells.

  8. The cysteine redox state of the monomer controls histidine dissociation rate constants and hence extrinsic ligand binding in human cytoglobin.

  9. The monomeric cytoglobin protein with an internal disulfide bond between the two cysteine residues Cys38 and Cys83, interacts with lipids to induce a change in haem co-ordination.

  10. Protein multimerization may be a mechanism that triggers physiological functions of human cytoglobin.

Cytoglobin (CYGB) Protein Profile

Protein Summary

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.

Gene names and symbols associated with Cytoglobin Proteins (CYGB)

  • cytoglobin 1 (cygb1)
  • cytoglobin (cygb)
  • cytoglobin (CYGB)
  • cytoglobin-1 (cygb1)
  • cytoglobin L homeolog (cygb.L)
  • cytoglobin (Cygb)
  • 3110001K20Rik protein
  • CYGB protein
  • cygb-1 protein
  • HGB protein
  • MGC84306 protein
  • MGC89562 protein
  • Staap protein
  • Stap protein
  • wu:fb77d07 protein
  • wu:fb93a03 protein
  • zgc:109806 protein

Protein level used designations for Cytoglobin Proteins (CYGB)

cyt , cytoglobin-1 , cytoglobin , histoglobin , stellate cell activation associated protein , stellate cell activation-associated protein , HGb

GENE ID SPECIES
246090 Danio rerio
448640 Xenopus (Silurana) tropicalis
707130 Macaca mulatta
739843 Pan troglodytes
100049376 Oryzias latipes
100136084 Oncorhynchus mykiss
100307038 Ovis aries
447575 Xenopus laevis
100224652 Taeniopygia guttata
100357278 Oryctolagus cuniculus
114886 Mus musculus
114757 Homo sapiens
427802 Gallus gallus
609341 Canis lupus familiaris
510299 Bos taurus
170520 Rattus norvegicus
100058726 Equus caballus
Selected quality suppliers for Cytoglobin Proteins (CYGB)
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