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anti-Cytotoxic and Regulatory T Cell Molecule (CRTAM) Antibodies

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A\; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009].. Additionally we are shipping CRTAM Proteins (10) and CRTAM Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CRTAM 56253 O95727
CRTAM 54698  
CRTAM 300649  
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Top anti-CRTAM Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat PE FACS, IP 100 μg Log in to see 10 to 12 Days
$320.68
Details
Mouse Rat APC FACS 100 μg Log in to see 10 to 12 Days
$353.29
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lymphoma labeled with Rabbit Anti CRTAM Polyclonal Antibody, Unconjugated (ABIN1387894) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse PE WB 100 Tests Log in to see 10 to 12 Days
$282.64
Details
Human Mouse APC BCA 100 Tests Log in to see 10 to 12 Days
$331.55
Details
Mouse Rat Un-conjugated FACS 500 μg Log in to see 10 to 12 Days
$570.71
Details
Mouse Rat Un-conjugated ELISA (Detection), ELISPOT (Detection) 100 μg Log in to see 10 to 12 Days
$260.89
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

CRTAM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CRTAM Antibodies

  1. Mouse (Murine) Monoclonal CRTAM Primary Antibody for FACS - ABIN2665676 : Arase, Takeuchi, Unno, Hirano, Yokosuka, Arase, Saito: Heterotypic interaction of CRTAM with Necl2 induces cell adhesion on activated NK cells and CD8+ T cells. in International immunology 2005 (PubMed)
    Show all 6 references for ABIN2665676

  2. Mouse (Murine) Monoclonal CRTAM Primary Antibody for ELISA (Detection), ELISPOT (Detection) - ABIN2664609 : Galibert, Diemer, Liu, Johnson, Smith, Walzer, Comeau, Rauch, Wolfson, Sorensen, Van der Vuurst de Vries, Branstetter, Koelling, Scholler, Fanslow, Baum, Derry, Yan: Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule. in The Journal of biological chemistry 2005 (PubMed)
    Show all 6 references for ABIN2664609

  3. Mouse (Murine) Monoclonal CRTAM Primary Antibody for FACS - ABIN2658202 : Boles, Barchet, Diacovo, Cella, Colonna: The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM. in Blood 2005 (PubMed)
    Show all 6 references for ABIN2658202

  4. Mouse (Murine) Monoclonal CRTAM Primary Antibody for FACS, IP - ABIN2662609 : Kennedy, Vicari, Saylor, Zurawski, Copeland, Gilbert, Jenkins, Zlotnik: A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). in Journal of leukocyte biology 2000 (PubMed)
    Show all 6 references for ABIN2662609

More Antibodies against CRTAM Interaction Partners

Human Cytotoxic and Regulatory T Cell Molecule (CRTAM) interaction partners

  1. These results reveal that CRTAM is critical to instruct the differentiation of CD4 (show CD4 Antibodies)(+)CTL through the induction of Eomes (show EOMES Antibodies) and CTL-related gene.

  2. CRTAM is negatively regulated by ZEB1 (show ZEB1 Antibodies) in T cells.

  3. Case-control studies reveal malignant mesothelioma risk associated with variants in the SDK1 (show SDK1 Antibodies), CRTAM and RASGRF2 (show RASGRF2 Antibodies) genes.

  4. The cell adhesion molecule (show MCAM Antibodies) Necl-2 (show CADM1 Antibodies) competitively binds the immune receptor CRTAM.

  5. The expression of CRTAM in activated Vgamma9Vdelta2 T cells is quickly downregulated following interaction with Necl-2 (show CADM1 Antibodies) on tumor cells.

  6. Three common variants in the class I MHC-restricted T cell-associated molecule gene were identified that were associated with an increased rate of asthma exacerbations based on the presence of a low circulating vitamin D level.

  7. Results show that CRTAM is a molecule involved in epithelial cell adhesion.

  8. Necl2 (show CADM1 Antibodies)/CRTAM molecular pair could regulate a large panel of cell/cell interactions both within and outside of the immune system

  9. NK cells and T8 cells recognize Necl-2 (show CADM1 Antibodies) through CRTAM, expressed only on activated cells. CRTAM-Necl-2 (show CADM1 Antibodies) interactions promote cytotoxicity of NK cells and IFN-gamma (show IFNG Antibodies) secretion of T8 cells as well as NK cell-mediated rejection of tumors expressing Necl-2 (show CADM1 Antibodies)

  10. CRTAM expression is driven by the JNK (show MAPK8 Antibodies)-AP-1 (show FOSB Antibodies) signaling pathway.

Mouse (Murine) Cytotoxic and Regulatory T Cell Molecule (CRTAM) interaction partners

  1. These results reveal that CRTAM is critical to instruct the differentiation of CD4 (show CD4 Antibodies)(+)CTL through the induction of Eomes (show EOMES Antibodies) and CTL-related gene.

  2. During pathogenic infection, Crtam-Cadm1 (show CADM1 Antibodies) interactions regulate the dynamic equilibrium between newly formed CD4 (show CD4 Antibodies)(+) T cells and their retention in the gut (show GUSB Antibodies).

  3. TCS upregulated the expression of tumor suppressor in lung cancer 1 (TSLC1 (show CADM1 Antibodies)) in 3LL tumor cells and the expression of its ligand, class I-restricted T cell-associated molecule (CRTAM), in effector T cells.

  4. In reciprocal crosses involving alcohol-preferring and alcohol-avoiding mouse strains, Crtam is identified as a candidate gene for alcohol preference.

  5. show that CRTAM has an unexpected constitutive expression in adult thymocytes and, remarkably, it is sustained during all stages of thymocyte development.

  6. Necl2 (show CADM1 Antibodies)/CRTAM molecular pair could regulate a large panel of cell/cell interactions both within and outside of the immune system

  7. NK cells and T8 cells recognize Necl-2 (show CADM1 Antibodies) through CRTAM, expressed only on activated cells. CRTAM-Necl-2 (show CADM1 Antibodies) interactions promote cytotoxicity of NK cells and IFN-gamma (show IFNG Antibodies) secretion of T8 cells as well as NK cell-mediated rejection of tumors expressing Necl-2 (show CADM1 Antibodies)

  8. CRTAM expression is critical for the accumulation of antigen-specific cytotoxic T lymphocytes and their subsequent proliferation within the draining lymph node.

CRTAM Antigen Profile

Protein Summary

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A\; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008

Gene names and symbols associated with CRTAM

  • cytotoxic and regulatory T cell molecule (CRTAM) antibody
  • cytotoxic and regulatory T cell molecule (crtam) antibody
  • cytotoxic and regulatory T cell molecule (Crtam) antibody
  • CD355 antibody
  • CRTAM antibody
  • cTADS antibody
  • MGC82176 antibody
  • TAD antibody

Protein level used designations for CRTAM

cytotoxic and regulatory T-cell molecule , thymocyte activation and development protein , thymocyte activation and developmental protein , cytotoxic and regulatory T cell molecule , class-I MHC-restricted T cell associated molecule , cytotoxic and regulatory T-cell molecule-like , class I MHC restricted T cell associated molecule , class-I MHC-restricted T-cell-associated molecule , class I-restricted T cell-associated molecule

GENE ID SPECIES
395342 Gallus gallus
446606 Xenopus laevis
610296 Canis lupus familiaris
707560 Macaca mulatta
736196 Pan troglodytes
100390057 Callithrix jacchus
100461531 Pongo abelii
100606471 Nomascus leucogenys
56253 Homo sapiens
781864 Bos taurus
54698 Mus musculus
300649 Rattus norvegicus
Selected quality suppliers for anti-CRTAM (CRTAM) Antibodies
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