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D-Dopachrome Tautomerase Proteins (DDT)

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. Additionally we are shipping D-Dopachrome Tautomerase Antibodies (66) and D-Dopachrome Tautomerase Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDT 29318 P80254
DDT 1652 P30046
DDT 13202 O35215
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Top D-Dopachrome Tautomerase Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,227.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,227.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,227.50
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$2,524.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$322.14
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$739.20
Details

DDT Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
,
Mouse (Murine)

Top referenced D-Dopachrome Tautomerase Proteins

  1. Human DDT Protein expressed in Escherichia coli (E. coli) - ABIN667020 : Sugimoto, Taniguchi, Nakagawa, Tanaka, Suzuki, Nishihira: Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution. in Biochemistry 1999 (PubMed)
    Show all 2 references for ABIN667020

More Proteins for D-Dopachrome Tautomerase (DDT) Interaction Partners

Human D-Dopachrome Tautomerase (DDT) interaction partners

  1. High MIF-2 levels are predictive of the development of organ dysfunction in myocardial ischemia reperfusion injury.

  2. Both p53 (show TP53 Proteins) wildtype and mutant human lung adenocarcinoma tumors rely on MIF (show AMH Proteins) family members for maximal cell growth and survival.

  3. findings identify DDT as a functionally redundant but more potent cytokine to MIF (show AMH Proteins) in cancer and suggest that current attempts to inhibit MIF (show AMH Proteins) signaling may fail because of DDT compensation.

  4. D-dopachrome tautomerase secreted from adipocytes acts on preadipocytes to promote IL-6 (show IL6 Proteins) expression and to inhibit adipogenesis by suppressing the induction of genes encoding adipogenic regulators

  5. DDT acts on adipocytes to regulate lipid metabolism through AMPK (show PRKAA1 Proteins) and/or PKA pathway(s) and improves glucose intolerance caused by obesity.

  6. These data indicate that D-DT is a MIF (show AMH Proteins)-like cytokine.

  7. D-DT-dependent beta-catenin (show CTNNB1 Proteins) stabilization is regulated by COX-2 expression, suggesting the existence of an amplification loop between COX-2- and beta-catenin (show CTNNB1 Proteins)-mediated transcription in these cells

  8. role of tautomerase active site of macrophage migration inhibitory factor (show MIF Proteins) as a potential target for discovery of novel anti-inflammatory agents

  9. DDT is for the first time demonstrated in the skin and can be related to inflammation, and its covariation with MIF (show AMH Proteins) strengthens this observation.

  10. D-dopachrome tautomerase (D-DT) and macrophage migration inhibitory factor (show MIF Proteins), individually and additively, promote vascular endothelial growth factor and CXCL8 (show IL8 Proteins) expression in human lung adenocarcinoma cell lines.

Mouse (Murine) D-Dopachrome Tautomerase (DDT) interaction partners

  1. cardiomyocyte secretion of DDT has important autocrine/paracrine effects during ischemia-reperfusion that protect the heart against injury

  2. These data point to a potential involvement of D-dopachrome tautomerase activity in the mature mouse brain, and suggest some functional and evolutionary relationship between innate immunity and tautomerization of D-dopachrome in mammalian species

  3. These data indicate that D-DT is a MIF (show MIF Proteins)-like cytokine.

D-Dopachrome Tautomerase (DDT) Protein Profile

Protein Summary

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22.

Gene names and symbols associated with D-Dopachrome Tautomerase Proteins (DDT)

  • D-dopachrome tautomerase (ddt)
  • D-dopachrome decarboxylase a (ddt-a)
  • D-dopachrome decarboxylase b (ddt-b)
  • D-dopachrome tautomerase (DDT)
  • D-dopachrome tautomerase (Ddt)
  • D-dopachrome tautomerase-like (LOC100337941)
  • C78655 protein
  • DDCT protein
  • DDT protein
  • ddt-a protein
  • ddt-b protein
  • wu:fb49f11 protein
  • zgc:86714 protein

Protein level used designations for D-Dopachrome Tautomerase Proteins (DDT)

D-dopachrome decarboxylase , D-dopachrome decarboxylase-A , D-dopachrome tautomerase-A , D-dopachrome decarboxylase-B , D-dopachrome tautomerase-B , D-dopachrome tautomerase , dopachrome isomerase , phenylpyruvate tautomerase II

GENE ID SPECIES
415237 Danio rerio
447275 Xenopus laevis
494727 Xenopus laevis
550015 Xenopus (Silurana) tropicalis
699070 Macaca mulatta
699933 Macaca mulatta
747265 Pan troglodytes
747294 Pan troglodytes
100301489 Taeniopygia guttata
29318 Rattus norvegicus
1652 Homo sapiens
607589 Canis lupus familiaris
615999 Bos taurus
13202 Mus musculus
416937 Gallus gallus
100155535 Sus scrofa
100337941 Oryctolagus cuniculus
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