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The protein encoded by DCTD catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. Additionally we are shipping DCMP Deaminase Proteins (16) and many more products for this protein.
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Human Polyclonal DCTD Primary Antibody for EIA, WB - ABIN951852
Rha, Jeung, Choi, Yang, Yoo, Kim, Roh, Chung: An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients. in The oncologist 2007
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The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
, dCMP deaminase
, Deoxycytidylate deaminase
, hypothetical protein
, conserved uncharacterised protein