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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 Proteins (DDX1)

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX1 Antibodies (42) and DDX1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDX1 1653 Q92499
Rat DDX1 DDX1 84474 Q641Y8
DDX1 104721 Q91VR5
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Top DDX1 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

DDX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Top referenced DDX1 Proteins

  1. Human DDX1 Protein expressed in Wheat germ - ABIN1351308 : Chou, Lin, Lin, Luber, Godbout, Mann, Chen: DEAD box protein DDX1 regulates cytoplasmic localization of KSRP. in PLoS ONE 2013 (PubMed)

More Proteins for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1) Interaction Partners

Fruit Fly (Drosophila melanogaster) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1) interaction partners

  1. These data suggest a role for Drosophila Ddx1 in stress-induced regulation of splicing.

  2. DEAD-box protein (show INTS6 Proteins) Bel (show LHX2 Proteins) has evolutionarily conserved roles in fertility and development.

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1) interaction partners

  1. crystal structure of the SPRY domain of human DDX1 (hDSPRY) is reported at 2.0 A resolution

  2. HIV-1 wild type Tat (show TAT Proteins) co-immunoprecipitated with DDX1.

  3. Data indicate a tight binding of DEAD-box protein DDX1 to adenosine diphosphate (ADP), one of the strongest affinities observed for DEAD-box helicases.

  4. hCLE/C14orf166 associates with DDX1, HSPC117, and FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.

  5. archease (also called ZBTB8OS), a protein of unknown function, is required for full activity of the human tRNA ligase complex and, in cooperation with DDX1, facilitates the formation of an RTCB-guanylate intermediate central to mammalian RNA ligation

  6. subcellular localization of KSRP (show KHSRP Proteins) is regulated by competing interactions with DDX1 or 14-3-3 (show YWHAQ Proteins)

  7. DDX1 depletion causes accumulation of DNA damage in response to cisplatin and defects in DNA repair of double-stranded breaks.

  8. DDX1 was shown to be an RNA-activated ATPase, wherein Rev-bound RNA was equally effective at stimulating ATPase activity as protein-free RNA.

  9. DDX1 acts as a cellular cofactor by promoting oligomerization of Rev on the Rev response element.

  10. elevated levels of DDX1 RNA or the presence of DDX1 in the cytoplasm could serve as an effective prognostic biomarker for early recurrence in primary breast cancer.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1) interaction partners

  1. we show that the transcript levels of an RNA helicase, Ddx1, regulates strain differences in the amount of nitric oxide produced by macrophage after stimulation with interferon gamma (show IFNG Proteins) and tumor necrosis factor (show TNF Proteins).

  2. Coronavirus N phosphorylation by GSK-3 allows recruitment of the RNA helicase DDX1, which facilitates template readthrough and enables longer viral positive-sense single-stranded genomic RNA synthesis.

  3. DDX1 promotes the expression of a subset of microRNAs. Knockdown of DDX1 promotes ovarian tumor invasion and metastasis.

  4. DDX1-DDX21 (show DDX21 Proteins)-DHX36 (show DHX36 Proteins) complex represents a dsRNA sensor that uses the TRIF (show RNF138 Proteins) pathway to activate type I IFN responses in the cytosol of myeloid dendritic cells

  5. DDX1 mRNA was produced in both seminoma and nonseminoma types of human testicular germ cell tumor samples

DDX1 Protein Profile

Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.

Gene names and symbols associated with DDX1

  • Dead-box-1 (Ddx1)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 (DDX1)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 1 (DDX1)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 1 (Ddx1)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 1 (ddx1)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 (ddx1)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 (Ddx1)
  • AA409185 protein
  • anon-79E protein
  • CG9054 protein
  • DBP-RB protein
  • Dbp79E protein
  • DDX1 protein
  • DmDDX1 protein
  • Dmel\\CG9054 protein
  • DmRH12 protein
  • si:ch211-214k9.2 protein
  • si:dkey-161f12.1 protein
  • UKVH5d protein

Protein level used designations for DDX1

CG9054-PA , Ddx1-PA , DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 , ATP-dependent RNA helicase DDX1 , DEAD box polypeptide 1 , DEAD box protein 1 , DEAD box protein retinoblastoma , DEAD box-1 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1 , DEAD box protein DDX1

40457 Drosophila melanogaster
698327 Macaca mulatta
100013419 Monodelphis domestica
1653 Homo sapiens
395249 Gallus gallus
475671 Canis lupus familiaris
84474 Rattus norvegicus
100037192 Xenopus laevis
100174133 Pongo abelii
556790 Danio rerio
510816 Bos taurus
104721 Mus musculus
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