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DDX56 encodes a member of the DEAD box protein family. Additionally we are shipping DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 56 Antibodies (70) and DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 56 Kits (10) and many more products for this protein.
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West Nile virus infection results in relocalization of DDX56 from nucleoli to virus assembly sites on the endoplasmic reticululm (ER), an observation that is consistent with a role for DDX56 in WNV virion assembly.
The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles.
Coimmunoprecipitation confirmed that capsid protein binds to human DDX56 in infected cells and that this interaction is required for assembly of infectious West Nile virus particles.
DDX26 (show INTS6 Proteins) maps to7p12, a region of frequent chromosome amplifications in glioblastoma involving the EGFR (show EGFR Proteins) gene.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
, RNA helicase II/Gu
, probable ATP-dependent RNA helicase DDX56
, DEAD/H box 56 RNA helicase/noh61
, probable ATP-dependent RNA helicase DDX56-like
, 61-kd nucleolar helicase
, ATP-dependent 61 kDa nucleolar RNA helicase
, DEAD box protein 21
, DEAD box protein 56
, DEAD-box RNA helicase
, nucleolar helicase of 61 kDa
, putative nucleolar RNA helicase
, nucleolar RNA helicase homolog