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anti-Defensin, alpha 6, Paneth Cell-Specific (DEFA6) Antibodies

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. Additionally we are shipping Defensin, alpha 6, Paneth Cell-Specific Kits (7) and Defensin, alpha 6, Paneth Cell-Specific Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DEFA6 613223  
DEFA6 1671 Q01524
DEFA6 13240 P50704
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Top anti-Defensin, alpha 6, Paneth Cell-Specific Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon labeled with Rabbit Anti-Defensin alpha 6 Polyclonal Antibody, Unconjugated (ABIN1715099) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$639.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of DEFA6 expression in transfected 293T cell line by DEFA6 monoclonal antibody (M01), clone 2D2.Lane 1: DEFA6 transfected lysate (Predicted MW: 11 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged DEFA6 is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Mouse Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Mouse Un-conjugated ELISA, WB   1000 μg Log in to see 8 to 10 Days
$1,277.83
Details
Mouse Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Mouse Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Mouse Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Mouse Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Mouse Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

DEFA6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) , ,


, , , , , , , , , , ,
Human ,
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Mouse (Murine) , ,


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More Antibodies against Defensin, alpha 6, Paneth Cell-Specific Interaction Partners

Human Defensin, alpha 6, Paneth Cell-Specific (DEFA6) interaction partners

  1. Paneth cell alpha-defensin 6 is an antimicrobial peptide (show cAMP Antibodies).

  2. Native HD-6 readily self-assembles into elongated fibrils observable by transmission electron microscopy, agglutinates both Gram-negative and -positive bacteria, and prevents the Listeria monocytogenes from invading cultured cells.

  3. Authors show that although NOD2 (show NOD2 Antibodies) by itself can slightly up-regulate expression of HD5 (show DEFA5 Antibodies) and HD6, it can strongly down-regulates their expression during differentiation of the Paneth cell lineage mainly by inhibiting activation of the MAPK (show MAPK1 Antibodies) pathway.

  4. In the meta-analysis, DEFA6 rs13275170 and DEFB1 (show DEFB1 Antibodies) rs2738169 had both a 1.3-fold increased odds ratio for gastric cancer.

  5. study reports that HD6 affords protection against invasion by enteric bacterial pathogens in vitro and in vivo; after stochastic binding to bacterial surface proteins, HD6 undergoes ordered self-assembly to form fibrils and nanonets that surround and entangle bacteria

  6. Defensin alpha 6 (DEFA 6) may have a role in adenoma but not in progression to colon carcinoma

  7. defensin (show DEF Antibodies) alpha6 is highly expressed in colon cancer cell lines

  8. Crystal structure of HD6.

  9. Human enteric defensin (show DEF Antibodies) (HD)-5 (show DEFA5 Antibodies) and HD-6 were detected in Paneth cells, which are observed in the gastric metaplastic mucosa as well as small intestinal epithelia.

Defensin, alpha 6, Paneth Cell-Specific (DEFA6) Antigen Profile

Protein Summary

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.

Gene names and symbols associated with DEFA6

  • defensin, alpha 6, Paneth cell-specific (DEFA6) antibody
  • defensin alpha 6 (Defa6) antibody
  • defensin, alpha 6 (DEFA6) antibody
  • defensin, alpha, 6 (Defa6) antibody
  • DEF6 antibody
  • DEFA6 antibody
  • Defcr6 antibody
  • HD-6 antibody

Protein level used designations for DEFA6

defensin, alpha 6, Paneth cell-specific , alpha-defensin 6, Paneth cell-specific , Paneth cell-specific alpha-defensin 6 , alpha-defensin 6 , defensin-6 , defensin 6 , alpha-defensin 6/12 , alpha-defensin, 6 , cryptdin-2 , defensin related cryptdin 6 , defensin-related cryptdin-6/12

GENE ID SPECIES
717000 Macaca mulatta
100307029 Equus caballus
613223 Rattus norvegicus
619354 Pan troglodytes
1671 Homo sapiens
13240 Mus musculus
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