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DEFA6 Products

(Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Jul 2008].

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Featured DEFA6 Categories

DEFA6 Antibodies

High quality antibodies with extensive validation data.

DEFA6 ELISA Kits

Reliable ELISA kits for a wide range of species.

DEFA6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DEFA6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN947789
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN7002006
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, ICC
Validations
  • (1)
Cat. No. ABIN7435730
Quantity 100 μL
Datasheet Datasheet

Recommended DEFA6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955308
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955309
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN1569380
Quantity 96 tests
Datasheet Datasheet

Recommended DEFA6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351414
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414954
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397885
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DEFA6 products

Shukla, Meena, Rao, Rao, Balazs, Rao: "Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine." in: Scientific reports, Vol. 8, Issue 1, pp. 16241, (2018) (PubMed).

van Beelen Granlund, Østvik, Brenna, Torp, Gustafsson, Sandvik: "REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation." in: Cell and tissue research, Vol. 352, Issue 3, pp. 639-46, (2013) (PubMed).

Lucero, Fallert Junecko, Klamar, Sciullo, Berendam, Cillo, Qin, Sui, Sanghavi, Murphey-Corb, Reinhart: "Macaque paneth cells express lymphoid chemokine CXCL13 and other antimicrobial peptides not previously described as expressed in intestinal crypts." in: Clinical and vaccine immunology : CVI, Vol. 20, Issue 8, pp. 1320-8, (2013) (PubMed).

Granlund, Beisvag, Torp, Flatberg, Kleveland, Ostvik, Waldum, Sandvik: "Activation of REG family proteins in colitis." in: Scandinavian journal of gastroenterology, Vol. 46, Issue 11, pp. 1316-23, (2011) (PubMed).

Synonyms and alternative names related to DEFA6

defensin alpha 6 (DEFA6), defensin, alpha 6, Paneth cell-specific (DEFA6), defensin alpha 6 (Defa6), defensin, alpha, 6 (Defa6), DEF6, DEFA6, Defcr6, HD-6

Protein level used designations for DEFA6

  • defensin, alpha 6, Paneth cell-specific
  • alpha-defensin 6, Paneth cell-specific
  • Paneth cell-specific alpha-defensin 6
  • alpha-defensin 6
  • defensin-6
  • defensin 6
  • alpha-defensin 6/12
  • alpha-defensin, 6
  • cryptdin-2
  • defensin related cryptdin 6
  • defensin-related cryptdin-6/12
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