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Dehydrodolichyl Diphosphate Synthase Proteins (DHDDS)

The protein encoded by DHDDS catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Additionally we are shipping Dehydrodolichyl Diphosphate Synthase Antibodies (22) and Dehydrodolichyl Diphosphate Synthase Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DHDDS 79947 Q86SQ9
DHDDS 67422 Q99KU1
Rat DHDDS DHDDS 298541  
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Top Dehydrodolichyl Diphosphate Synthase Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

DHDDS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Dehydrodolichyl Diphosphate Synthase (DHDDS) Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Dehydrodolichyl Diphosphate Synthase (DHDDS) interaction partners

  1. isolation and characterization of dehydrodolichyl diphosphate synthase and determination of its mRNA abundance in two different strains, STEELHEAD and BORN

Zebrafish Dehydrodolichyl Diphosphate Synthase (DHDDS) interaction partners

  1. These results demonstrate that suppression of DHDDS expression in zebrafish leads to the loss of photoreceptor outer segments and visual function.

Human Dehydrodolichyl Diphosphate Synthase (DHDDS) interaction partners

  1. We identified the MAK (show MAK Proteins) and DHDDS mutations homozygously in only 2.1% and 0.8%, respectively, of patients of mixed ethnicity, but in 25.7% and 8.6%, respectively, of cases reporting Jewish ancestry

  2. A single-nucleotide mutation in the gene that encodes DHDDS has been identified by whole exome sequencing as the cause of the non-syndromic recessive retinitis pigmentosa (RP) in a family of Ashkenazi Jewish origin.

  3. A missense mutation in DHDDS is associated with autosomal-recessive retinitis pigmentosa.

  4. A variant in DHDDS is associated with retinitis pigmentosa.

  5. identification and characterization; overexpression of CIT (show CIT Proteins) in CHO cells results in a modest increase in cis-isoprenyltransferase activity associated with microsomal fractions

  6. molecular cloning; results suggest a regulatory relationship between CPT (show CHPT1 Proteins) activity and dolichol biosynthesis, and may implicate CPT (show CHPT1 Proteins) in the levels of dolichol-oligosaccharide intermediate biosynthesis

Dehydrodolichyl Diphosphate Synthase (DHDDS) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with DHDDS

  • dehydrodolichyl diphosphate synthase (DHDDS)
  • dehydrodolichyl diphosphate synthase (Dhdds)
  • dehydrodolichyl diphosphate synthase (dhdds)
  • 3222401G21Rik protein
  • CIT protein
  • CPT protein
  • DS protein
  • HDS protein
  • RP59 protein
  • W91638 protein
  • wu:fd56c06 protein
  • zgc:77088 protein

Protein level used designations for DHDDS

dehydrodolichyl diphosphate synthase , cis-IPTase , cis-isoprenyltransferase , cis-prenyl transferase , dedol-PP synthase , epididymis tissue protein Li 189m

GENE ID SPECIES
456662 Pan troglodytes
732991 Bombyx mori
100135207 Xenopus (Silurana) tropicalis
100286813 Oncorhynchus mykiss
406468 Danio rerio
398626 Xenopus laevis
419543 Gallus gallus
79947 Homo sapiens
612157 Canis lupus familiaris
523264 Bos taurus
67422 Mus musculus
298541 Rattus norvegicus
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