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DNASE1L3 encodes a member of the deoxyribonuclease I family. Additionally we are shipping DNASE1L3 Kits (9) and DNASE1L3 Proteins (5) and many more products for this protein.
Showing 10 out of 46 products:
Human Polyclonal DNASE1L3 Primary Antibody for WB - ABIN657806
Okamoto, Okamoto, Yashiro, Shiokawa, Sunaga, Yoshimori, Tanuma, Kitamura: Involvement of DNase gamma in the resected double-strand DNA breaks in immunoglobulin genes. in Biochemical and biophysical research communications 2005
Cloning and apoptotic DNase (show DNASE2 Antibodies) activity of Xenopus laevis DNase gamma
Study reports that DNASE1L3-deficient mice rapidly develop autoantibodies to DNA and chromatin, followed by an systemic lupus erythematosus-like disease. Circulating DNASE1L3 is produced by dendritic cells and macrophages, and its levels inversely correlate with anti-DNA antibody response.
DNase gamma, but not CAD (show CAD Antibodies), is the effector endonuclease for INDF in cells undergoing necrosis.
A comparison of the expression and transport of DNAse1 (show DNASE1 Antibodies) from rats and DNAse1L3 from mice is reported.
These results suggest that DNasegamma provides an alternative mechanism for inducing nuclear changes when the working apoptotic cascade is unsuitable for caspase-activated DNase (show DFFB Antibodies) activation.
serum contains two nucleases, DNase1 (show DNASE1 Antibodies) and DNase1l3, which may substitute or cooperate with each other during DNA degradation, providing effective clearance after exposure or release from dying cells.
Data indicate a likely functional variant influencing scleroderma susceptibility at deoxyribonuclease I-like 3 protein DNASE1L3 missense polymorphism rs35677470.
Single nucleotide polymorphisms in the DNASE1L3 is associated with autoimmune diseases.
DNASE1L3 mutations occur in hypocomplementemic urticarial vasculitis syndrome.
These results suggest a cooperative activity between CAD (show CAD Antibodies) and DNAS1L3 to accomplish internucleosomal DNA fragmentation .
We identified a rare autosomal recessive form of systemic lupus erythematosus, in which autozygome analysis revealed a null mutation in the DNASE1L3 gene
investigates the distribution of DNASE1L3 gene SNPs in exons of the gene in eight Asian, three African, and three Caucasian populations worldwide using newly devised genotyping methods.
The Poly(ADP-ribose) polymerase-1 (show PARP1 Antibodies)-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells.
Identification of two functional nuclear localization signals in DNase gamma that have a role in apoptotic DNA fragmentation.
DNase gamma is involved in the generation of resected double-strand DNA breaks associated with somatic hypermutation
DNAS1L3 plays an active role in lymphoma cell sensitization to VP-16 and its deficiency may constitute a novel mechanism of drug resistance in these cells
This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
deoxyribonuclease I-like 3
, deoxyribonuclease gamma
, deoxyribonuclease 1-like 3
, DNase I homolog protein DHP2
, DNase I-like 3
, DNase gamma
, liver and spleen DNase
, macrophage specific DNase I
, DNase I homolog protein 2
, Liver and spleen DNase
, deoxyribonuclease I-like III