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The protein encoded by DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Additionally we are shipping Desmocollin 1 Proteins (10) and Desmocollin 1 Kits (8) and many more products for this protein.
Showing 10 out of 44 products:
Human Monoclonal Desmocollin 1 Primary Antibody for IHC (fro), IHC (p) - ABIN112238
Akat, Mennel, Kremer, Gassler, Bleck, Kartenbeck: Molecular characterization of desmosomes in meningiomas and arachnoidal tissue. in Acta neuropathologica 2003
Show all 5 references for ABIN112238
Human Polyclonal Desmocollin 1 Primary Antibody for EIA, WB - ABIN453627
Descargues, Deraison, Prost, Fraitag, Mazereeuw-Hautier, DAlessio, Ishida-Yamamoto, Bodemer, Zambruno, Hovnanian: Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome. in The Journal of investigative dermatology 2006
Low expression of DSC 1 (show RCAN1 Antibodies), 2, and 3 was observed in 55, 54, and 79 % of liver metastases.
High expression of desmocollin 1 (DSC1) was observed in 41.6%, DSC2 (show DSC2 Antibodies) in 58.0%, DSC3 (show DSC2 Antibodies) in 61.4%, E-cadherin (show CDH1 Antibodies) in 71.4%, CDX2 (show CDX2 Antibodies) in 58.0%, PITX1 (show PITX1 Antibodies) in 55.0%, CDK4 (show CDK4 Antibodies) in 0.2%, TLE1 (show TLE1 Antibodies) in 1.3%, Factor H (show CFH Antibodies) in 42.5%, and MDM2 (show MDM2 Antibodies) in 0.2% of colorectal carcinomas.
The ultrastructural modifications of desmosomes during terminal differentiation of hair follicles are paralleled by the modulation of the synthesis of desmocollin 1.
in majority of patients with Netherton syndrome (show SPINK5 Antibodies), Dsg1 (show DSG1 Antibodies) & Dsc1 (show RCAN1 Antibodies) were reduced in living layers of epidermis; SCTE (show KLK5 Antibodies)-like & SCCE (show KLK7 Antibodies)-like activities were increased, suggesting these proteases participate in premature degradation of corneodesmosomal cadherins
Increased Dsc1 (show RCAN1 Antibodies) protein is associated with colorectal cancer
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
, cadherin family member 1
, desmosomal glycoprotein 2/3