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anti-Desmoglein 2 (DSG2) Antibodies

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Additionally we are shipping Desmoglein 2 Kits (7) and Desmoglein 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DSG2 1829 Q14126
DSG2 13511 O55111
DSG2 307562  
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Top anti-Desmoglein 2 Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   50 μg Log in to see 6 to 8 Days
$357.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), IF, IHC (p), WB   50 μg Log in to see 6 to 8 Days
$346.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, IF, IP, WB 0.1 mL Log in to see 5 to 6 Days
$486.22
Details
Human Mouse Un-conjugated FACS, IF, IP, WB   0.1 mg Log in to see 6 to 8 Days
$489.50
Details
Human Mouse Un-conjugated ICC, IF, WB 0.1 mL Log in to see 5 to 6 Days
$486.22
Details
Human Mouse Un-conjugated IHC (fro), IP, WB   25 μg Log in to see 6 to 8 Days
$253.00
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p), WB   5 mL Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Dsg2  Sample Tissue: Mouse Testis lysates  ... 100 μL Log in to see 2 to 3 Days
$289.00
Details

DSG2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-Desmoglein 2 Antibodies

  1. Cow (Bovine) Monoclonal Desmoglein 2 Primary Antibody for IHC (fro), IF - ABIN111817 : Yang, Shaio, Wang, Wu, Stone: Neuroblastoma cell-mediated leukocyte chemotaxis: lineage-specific differentiation of interleukin-8 expression. in Experimental cell research 1994 (PubMed)
    Show all 9 references for ABIN111817

  2. Human Monoclonal Desmoglein 2 Primary Antibody for FACS, IF - ABIN1106982 : Wahl: Generation of monoclonal antibodies specific for desmoglein family members. in Hybridoma and hybridomics 2002 (PubMed)
    Show all 8 references for ABIN1106982

  3. Human Monoclonal Desmoglein 2 Primary Antibody for EIA, IHC (fro) - ABIN112136 : Franke, Nuber, Schmidt, Schäfer: Desmosomes--dual junctional principles of intra- and supracellular order in epithelial differentiation and tissue formation. in Verhandlungen der Deutschen Gesellschaft für Pathologie 1995 (PubMed)
    Show all 6 references for ABIN112136

  4. Human Monoclonal Desmoglein 2 Primary Antibody for EIA, IHC (fro) - ABIN112242 : Demlehner, Schäfer, Grund, Franke: Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle. in The Journal of cell biology 1995 (PubMed)
    Show all 3 references for ABIN112242

  5. Human Polyclonal Desmoglein 2 Primary Antibody for EIA, WB - ABIN360106 : Posch, Posch, Geier, Erdmann, Mueller, Richter, Ruppert, Pankuweit, Maisch, Perrot, Buttgereit, Dietz, Haverkamp, Ozcelik: A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy. in Molecular genetics and metabolism 2008 (PubMed)
    Show all 2 references for ABIN360106

  6. Human Polyclonal Desmoglein 2 Primary Antibody for IHC, WB - ABIN2782147 : Cirillo, Lanza, De Rosa, Cammarota, La Gatta, Gombos, Lanza: The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery. in Journal of cellular biochemistry 2008 (PubMed)
    Show all 2 references for ABIN2782147

  7. Human Monoclonal Desmoglein 2 Primary Antibody for ICC, IF - ABIN1169682 : Keim, Johnson, Wheelock, Wahl: Generation and characterization of monoclonal antibodies against the proregion of human desmoglein-2. in Hybridoma (2005) 2008 (PubMed)

More Antibodies against Desmoglein 2 Interaction Partners

Zebrafish Desmoglein 2 (DSG2) interaction partners

Human Desmoglein 2 (DSG2) interaction partners

  1. a novel pathway of CSTA (show CSTA Antibodies) regulation involving Dsg2

  2. DSG2 and DSG3 (show DSG3 Antibodies) might be potential diagnostic markers for squamous cell carcinoma of the lung.

  3. In endometrial luminal epithelium, cadherin 6 (show CDH6 Antibodies), desmoglein 2 and plexin b2 (show PLXNB2 Antibodies) were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity.

  4. a low DSG2 expression phenotype is a useful prognostic biomarker of tumor aggressiveness and may serve as an aid in identifying patients with clinically significant prostate cancer.

  5. Six variants of uncertain clinical significance in the PKP2 (show PKP2 Antibodies), JUP (show JUP Antibodies), and DSG2 genes showed a deleterious effect on mRNA splicing, indicating these are ARVD (show TGFB3 Antibodies)/C-related pathogenic splice site mutations.

  6. This structure reveals that the ectodomain of Dsg2 is flexible even in the calcium-bound state and, on average, is shorter than the type 1 cadherin crystal structures.

  7. Data demonstrate that partner desmosomal cadherins Dsg2 and Dsc2 (show DSC2 Antibodies) play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (show EGFR Antibodies) signaling.

  8. Desmoglein 2 expression attenuates migration of melanoma cells, mediated by downregulation of secretogranin II (show SCG2 Antibodies).

  9. Reduced cardiac desmoglein-2 and desmocollin-2 (show DSC2 Antibodies) levels appear to be specifically associated with Arrhythmogenic right ventricular Dysplasia/cardiomyopathy, independent of underlying mutations.

  10. Gal3 has a role in stabilizing desmoglein-2, a desmosomal cadherin, and intercellular adhesion in intestinal epithelial cells

Mouse (Murine) Desmoglein 2 (DSG2) interaction partners

  1. Data suggest that loss of desmoglein 2 (Dsg2) compromises adhesion, and that this is a major pathogenic mechanism in DSG2-related and probably other desmosome-related arrhythmogenic cardiomyopathy (AC).

  2. Dsg2 modulates Gli1 (show GLI1 Antibodies) expression. Dsg2-mediated hyperproliferation, MEK (show MDK Antibodies)/Erk1/2 (show MAPK1/3 Antibodies) activation, and accelerated squamous tumor development are enhanced on the Ptc1 (show PTCH1 Antibodies)+/lacZ (show GLB1 Antibodies) background.

  3. a novel pathway of CSTA (show CSTA Antibodies) regulation involving Dsg2

  4. Data demonstrate that desmoglein-2 plays a critical role in cardiomyocyte cohesion and function.

  5. Data demonstrate that partner desmosomal cadherins Dsg2 and Dsc2 (show DSC2 Antibodies) play opposing roles in controlling colonic carcinoma cell proliferation through differential effects on EGFR (show EGFR Antibodies) signaling.

  6. Dsg2 compensates for Dsg3 (show DSG3 Antibodies) depletion with regard to cell cohesion, but does not regulate p38 MAPK (show MAPK14 Antibodies) signaling.

  7. In vivo interaction between Dsg2 and Na(V)1.5 provides a molecular pathway for the observed electrical disturbances during the early arrhythmogenic right ventricular cardiomyopathy.

  8. Mutant desmoglein 2 cannot support the increased requirements placed on intercalated disc adhesion during postnatal heart development. This induces cardiomyocyte death, aseptic inflammation and fibrotic replacement.

  9. ventricular arrhythmias that has been linked to mutations in desmosomal proteins including desmoglein 2

  10. Myocyte necrosis underlies progressive myocardial dystrophy in N271S-dsg2-related arrhythmogenic right ventricular cardiomyopathy.

Desmoglein 2 (DSG2) Antigen Profile

Protein Summary

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Gene names and symbols associated with anti-Desmoglein 2 (DSG2) Antibodies

  • desmoglein 2 (DSG2) antibody
  • desmoglein 2 (dsg2) antibody
  • desmoglein 2 (LOC100348149) antibody
  • desmoglein 2 (Dsg2) antibody
  • AA408168 antibody
  • ARVC10 antibody
  • ARVD10 antibody
  • CDHF5 antibody
  • CMD1BB antibody
  • D18Ertd293e antibody
  • dsc antibody
  • DSG2 antibody
  • dsga antibody
  • HDGC antibody
  • si:dkeyp-51f12.6 antibody
  • wu:fj23f02 antibody

Protein level used designations for anti-Desmoglein 2 (DSG2) Antibodies

desmoglein 2 , Dsg alpha , desmocollin a , desmoglein-2-like , HDGC , cadherin family member 5 , desmoglein-2

GENE ID SPECIES
100066038 Equus caballus
428529 Gallus gallus
455356 Pan troglodytes
560026 Danio rerio
705805 Macaca mulatta
100348149 Oryctolagus cuniculus
100456327 Pongo abelii
100565052 Anolis carolinensis
1829 Homo sapiens
13511 Mus musculus
307562 Rattus norvegicus
490500 Canis lupus familiaris
100625833 Sus scrofa
508151 Bos taurus
Selected quality suppliers for anti-Desmoglein 2 (DSG2) Antibodies
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