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anti-Desmoglein 4 (DSG4) Antibodies

DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. Additionally we are shipping Desmoglein 4 Proteins (8) and Desmoglein 4 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DSG4 147409 Q86SJ6
DSG4 16769 Q7TMD7
DSG4 291754 Q6W3B0
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Top anti-Desmoglein 4 Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Guinea Pig Un-conjugated IHC (fro)   0.1 mL Log in to see 6 to 8 Days
$478.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Desmoglein 4 expression in HEK293T (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated IHC   0.1 mg Log in to see 5 to 7 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DSG4 is 0.03 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Sheep Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$581.17
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 3 to 7 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 3 to 7 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 3 to 7 Days
$357.50
Details

DSG4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Desmoglein 4 Antibodies

  1. Human Polyclonal Desmoglein 4 Primary Antibody for IHC - ABIN966012 : Kljuic, Bazzi, Sundberg, Martinez-Mir, OShaughnessy, Mahoney, Levy, Montagutelli, Ahmad, Aita, Gordon, Uitto, Whiting, Ott, Fischer, Gilliam, Jahoda, Morris, Panteleyev, Nguyen, Christiano: Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. in Cell 2003 (PubMed)
    Show all 5 references for ABIN966012

  2. Human Polyclonal Desmoglein 4 Primary Antibody for IHC (fro) - ABIN401676 : Bazzi, Getz, Mahoney, Ishida-Yamamoto, Langbein, Wahl, Christiano: Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle. in Differentiation; research in biological diversity 2006 (PubMed)

More Antibodies against Desmoglein 4 Interaction Partners

Human Desmoglein 4 (DSG4) interaction partners

  1. This study further extends the body of evidence that mutations in the DSG4 gene result in both hypotrichosis and monilethrix-like scalp hair.

  2. Epitopes of Dsg4 may play a role in the pathogenesis of pemphigus vulgaris (show DSG3 Antibodies) .

  3. show that HOXC13, LEF1 (show LEF1 Antibodies) and FOXN1 (show FOXN1 Antibodies) repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch (show NOTCH1 Antibodies) pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.

  4. the human desmoglein 4 gene (DSG4) demonstrates that it is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 (show DSG1 Antibodies) and DSG3 (show DSG3 Antibodies).

  5. The essential role of desmoglein 4 in skin was established by identifying mutations in families with inherited hypotrichosis, as well as in the lanceolate hair mouse. We also show that DSG4 is an autoantigen in pemphigus vulgaris (show DSG3 Antibodies).

  6. DSG4 is pathogenic in pemphigus and staphylococcal scalded skin syndrome.

  7. The DSG4 protein is expressed in the more highly differentiated layers of the epidermis.

  8. identification of a single nucleotide deletion within exon 3 of DSG4, designated 87delG in a Pakistani family with localized autosomal recessive hypotrichosis; this results in a frameshift and premature termination codon 162 bp downstream of the deletion

Mouse (Murine) Desmoglein 4 (DSG4) interaction partners

  1. show that HOXC13, LEF1 (show LEF1 Antibodies) and FOXN1 (show FOXN2 Antibodies) repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch (show NOTCH1 Antibodies) pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.

  2. Mast cell hyperplasia is associated with Dsg4-deficient hypotrichosis mice.

  3. Smad4 (show SMAD4 Antibodies) loss-associated Dsg4 depletion contributed, at least in part, to hair follicles degeneration in Smad4 (show SMAD4 Antibodies) deficient skin.

Desmoglein 4 (DSG4) Antigen Profile

Protein Summary

This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Desmoglein 4 (DSG4) Antibodies

  • desmoglein 4 (DSG4) antibody
  • desmoglein 4 (Dsg4) antibody
  • CDGF13 antibody
  • CDHF13 antibody
  • DSG4 antibody
  • lah antibody

Protein level used designations for anti-Desmoglein 4 (DSG4) Antibodies

desmoglein 4 , desmoglein-4-like , CDH family member 13 , cadherin family member 13 , desmoglein-4 , lanceolate hair

GENE ID SPECIES
537755 Bos taurus
612592 Canis lupus familiaris
743297 Pan troglodytes
100065957 Equus caballus
100414081 Callithrix jacchus
100454393 Pongo abelii
100468693 Ailuropoda melanoleuca
100543458 Meleagris gallopavo
100591286 Nomascus leucogenys
147409 Homo sapiens
16769 Mus musculus
291754 Rattus norvegicus
Selected quality suppliers for anti-Desmoglein 4 (DSG4) Antibodies
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