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Could have a role in patterning the central nervous system during embryogenesis. Additionally we are shipping DBX1 Antibodies (30) and many more products for this protein.
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Dbx1-derived neurons are essential for the transgenic expression and generation of respiratory behavior both in vitro and in vivo.
The present data emphasize that synaptic properties of excitatory interneurons of the respiratory rhythmogenic kernel, derived from Dbx1-expressing precursors, may provide the core logic underlying the rhythm for breathing.
activity of a single developmentally regulated gene, Dbx1, is a shared requirement for the specification of hypothalamic nuclei governing a subset of innate behaviors.
Dbx1 deficiency via laser ablation of neurons in the pre-Botzinger complex stops inspiratory rhythm and impairs output in neonatal mice.
These data define Dbx1 as a direct SOX3 (show SOX3 Proteins) target gene.
a single transcription factor, Dbx1, has an essential function in assigning midline-crossing identity, thereby contributing crucially to the establishment of the wiring laterality in the developing nervous system
dbx1-expressing cells have a unique function during head development, notably by controlling cell survival in a non cell-autonomous manner
Loss of septum Dbx1-derived Cajal-Retzius (CR) cells in the rostromedial pallium between E10.5 and E11.5 results in the redistribution of CR subtypes.
two spatially distinct and early-specified telencephalic progenitor pools marked by the homeodomain transcription factor Dbx1 are major sources of neuronal cell diversity in the mature mouse amygdala
Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
developing brain homeobox 1
, developing brain homeobox protein 1
, homeobox protein DBX1
, Mmox C
, homeodomain protein dbx