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DAGLA encodes a diacylglycerol lipase. Additionally we are shipping DAGLA Antibodies (58) and many more products for this protein.
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In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH (show FAAH Proteins)) and monoacylglycerol lipase (MAGL (show MGLL Proteins)) mRNAs were down-regulated in obese subjects, but the diets had no influence.
PLC (show HSPG2 Proteins)-beta1 and DAGL-alpha are detected in discrete brain regions, with a marked predominance of pyramidal morphologies of positive cortical cells.[review]
DAGLalpha mRNA expression is lowest in early life and adulthood, peaking between school age and young adulthood.
This gene was functionally characterized as a diacylglycerol-lipase (show LIPG Proteins) (DAGL), specifically referred to as DAGL alpha. This enzyme may play a role in the biosynthesis of the endocannbinoid 2-arachidonoylglycerol (2-AG).
Results demonstrate that mice with a deletion of the DAGL-alpha enzyme show a phenotype of increased emotional or stress-related behaviors. This is characterized by a reduced exploration of the central area of the open field, a maternal neglect behavior, a fear extinction deficit, increased behavioral despair, increased anxiety-related behaviors in the light/dark box, and reduced hippocampal neurogenesis
Authors demonstrated that phospholipase D and diacylglycerol lipase (show LIPG Proteins) were required for providing arachidonic acid for prostaglandin E(2) biosynthesis.
In corpus striatum diacylglycerol lipase-alpha activity is regulated by calcium/calmodulin dependent protein kinase (CaMK-II).
DAGLalpha is the major biosynthetic enzyme for 2-AG in the nervous system and reveal an essential role for this enzyme in regulating retrograde synaptic plasticity and adult neurogenesis.
This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.
diacylglycerol lipase, alpha
, neural stem cell-derived dendrite regulator
, sn1-specific diacylglycerol lipase alpha-like
, sn1-specific diacylglycerol lipase alpha