You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Dihydrolipoamide Branched Chain Transacylase E2 (DBT) Antibodies

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. Additionally we are shipping DBT Kits (6) and DBT Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DBT 1629 P11182
DBT 13171 P53395
DBT 29611  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-DBT Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-DBT Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC201998 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-DBT antibody (ABIN2455792), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DBT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DBT. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of DBT expression in transfected 293T cell line by DBT MaxPab polyclonal antibody.Lane 1: DBT transfected lysate(53.02 KDa).Lane 2: Non-transfected lysate. DBT MaxPab polyclonal antibody. Western Blot analysis of DBT expression in human liver. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB DBT antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X DBT antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated WB Western Blot analysis of DBT expression in transfected 293T cell line by DBT MaxPab polyclonal antibody.Lane 1: DBT transfected lysate(53.50 KDa).Lane 2: Non-transfected lysate. DBT MaxPab rabbit polyclonal antibody. Western Blot analysis of DBT expression in human kidney. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 16 Days
$675.71
Details

DBT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-DBT Antibodies

  1. Human Polyclonal DBT Primary Antibody for WB - ABIN514887 : Johnson, Vidoni, Durigon, Pearce, Rorbach, He, Brea-Calvo, Minczuk, Reyes, Holt, Spinazzola: Amino acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis. in PLoS ONE 2014 (PubMed)

  2. Chicken Polyclonal DBT Primary Antibody for IHC, WB - ABIN2784728 : Flaschker, Feyen, Fend, Simon, Schadewaldt, Wendel: Description of the mutations in 15 subjects with variant forms of maple syrup urine disease. in Journal of inherited metabolic disease 2007 (PubMed)

More Antibodies against DBT Interaction Partners

Human Dihydrolipoamide Branched Chain Transacylase E2 (DBT) interaction partners

  1. The novel DBT mutation c.650-651insT was more prevalent than the deleted 4.7-kb heterozygote in the Amis population. The reported 4.7-kb deletion indicating a possible founder mutation may be preserved.

  2. Deletion in DBT gene is associated with maple syrup urine disease.

  3. 4 novel mutations in DBT gene resulting in intermittent maple syrup urine disease in 7 Norwegian patients; pathogenic effect of the mutations is depletion of cellular protein; intermittent form of MSUD appears to be due to residual R301C mutant protein

  4. in our cohort more severe enzyme & clinical phenotypes of variant maple syrup urine disease were mainly associated with specific genotypes in BCKDHA (show BCKDHA Antibodies) gene; milder enzyme & clinical phenotypes were associated with specific genotypes in BCKDHB (show BCKDHB Antibodies) & DBT genes

  5. 30 Maple syrup urine disease Portuguese patients studied; 17 putative mutations have been identified (6 in BCKDHA (show BCKDHA Antibodies), 5 in BCKDHB (show BCKDHB Antibodies) and 6 in DBT); 7 of are described for the first time.

  6. Examination of the deletion mutation in the E2 (DBT) gene facilitated early MSUD diagnosis and was beneficial for the determination of the proper course of treatment.

  7. In 37% (12 patients) of a total of 64 alleles, the supposed maple syrup urine disease-causing mutations in Turkish patients were located in the BCKDHA (show BCKDHA Antibodies) gene, in 44% (14 patients) in the BCKDHB (show BCKDHB Antibodies) gene and in 19% (6 patients) in the DBT gene.

  8. two novel type IB MSUD mutations in Israeli patients, which affect the E1beta (show PDHB Antibodies) subunit in the decarboxylase (E1) component of the branched-chain alpha-ketoacid dehydrogenase complex

  9. Mutation in DBT causes a subset of maple syrup urine disease in Ashkenazi Jewish population.

Zebrafish Dihydrolipoamide Branched Chain Transacylase E2 (DBT) interaction partners

  1. que mutant larvae exhibit a progressive locomotor defect that culminates in unusual nose-to-tail compressions and an inability to swim. Peripheral nerve recordings demonstrate abnormal locomotor output to the axial muscles used for swimming.

Cow (Bovine) Dihydrolipoamide Branched Chain Transacylase E2 (DBT) interaction partners

  1. This gating mechanism synchronizes the binding of the two substrates to the active-site channel, which serves as a feed-forward switch to coordinate the E2b-catalyzed acyltransfer reaction.

DBT Antigen Profile

Protein Summary

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with DBT

  • dihydrolipoamide branched chain transacylase E2 (DBT) antibody
  • dihydrolipoamide branched chain transacylase E2 (dbt) antibody
  • dihydrolipoamide branched chain transacylase E2 (CpipJ_CPIJ006326) antibody
  • dihydrolipoamide branched chain transacylase E2 (BDBG_05874) antibody
  • dihydrolipoamide branched chain transacylase E2 (NAEGRDRAFT_78509) antibody
  • dihydrolipoamide branched chain transacylase E2 (VDBG_04820) antibody
  • dihydrolipoamide branched chain transacylase E2 (PGTG_17722) antibody
  • dihydrolipoamide branched chain transacylase E2 (Dbt) antibody
  • BCATE2 antibody
  • BCKAD-E2 antibody
  • BCKADE2 antibody
  • D3Wsu60e antibody
  • E2 antibody
  • E2b antibody
  • im:7147214 antibody
  • zgc:103768 antibody

Protein level used designations for DBT

lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial , dihydrolipoamide branched chain transacylase E2 , BCKAD E2 subunit , E2 component of branched chain alpha-keto acid dehydrogenase complex , branched chain acyltransferase, E2 component , branched-chain alpha-keto acid dehydrogenase complex component E2 , dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex , dihydrolipoyl transacylase , dihydrolipoyllysine-residue (2-methylpropanoyl)transferase , lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex , mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b) , BCKAD E2 , BCKAD-E2 , BCKADE2 , branched-chain alpha-ketoacid dehydrogenase, E2 subunit , part of the BCKAD complex , que , mitochondrial branched-chain alpha-keto acid dihydrolipoyl acyltransferase , component of branched chain keto acid dehydrogenase complex

GENE ID SPECIES
457056 Pan troglodytes
100174565 Pongo abelii
549717 Xenopus (Silurana) tropicalis
711547 Macaca mulatta
100050317 Equus caballus
100156530 Sus scrofa
100346987 Oryctolagus cuniculus
6038202 Culex quinquefasciatus
8503735 Ajellomyces dermatitidis SLH14081
8862102 Naegleria gruberi strain NEG-M
9530433 Verticillium alfalfae VaMs.102
10529473 Puccinia graminis f. sp. tritici CRL 75-36-700-3
1629 Homo sapiens
13171 Mus musculus
29611 Rattus norvegicus
541388 Danio rerio
447616 Xenopus laevis
395374 Gallus gallus
479929 Canis lupus familiaris
280759 Bos taurus
Selected quality suppliers for anti-DBT (DBT) Antibodies
Did you look for something else?