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DBT Products

(Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

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The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Featured DBT Categories

DBT Antibodies

High quality antibodies with extensive validation data.

DBT ELISA Kits

Reliable ELISA kits for a wide range of species.

DBT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DBT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN514887
Quantity 50 μg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (4)
Cat. No. ABIN6745750
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN947782
Quantity 100 μg
Datasheet Datasheet

Recommended DBT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6966364
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1140790
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1140789
Quantity 96 tests
Datasheet Datasheet

Recommended DBT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN3134462
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN3084921
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2719240
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our DBT products

Johnson, Vidoni, Durigon, Pearce, Rorbach, He, Brea-Calvo, Minczuk, Reyes, Holt, Spinazzola: "Amino acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis." in: PLoS ONE, Vol. 9, Issue 4, pp. e93597, (2014) (PubMed).

Fredersdorf, Milne, Hall, Lu: "Characterization of a panel of novel anti-p21Waf1/Cip1 monoclonal antibodies and immunochemical analysis of p21Waf1/Cip1 expression in normal human tissues." in: The American journal of pathology, Vol. 148, Issue 3, pp. 825-35, (1997) (PubMed).

Levine: "p53, the cellular gatekeeper for growth and division." in: Cell, Vol. 88, Issue 3, pp. 323-31, (1997) (PubMed).

Synonyms and alternative names related to DBT

dihydrolipoamide branched chain transacylase E2 (DBT), dihydrolipoamide branched chain transacylase E2 (dbt), dihydrolipoamide branched chain transacylase E2 (CpipJ_CPIJ006326), dihydrolipoamide branched chain transacylase E2 (BDBG_05874), dihydrolipoamide branched chain transacylase E2 (NAEGRDRAFT_78509), dihydrolipoamide branched chain transacylase E2 (VDBG_04820), hypothetical protein (PGTG_17722), dihydrolipoamide branched chain transacylase E2 (Dbt), dihydrolipoamide branched chain transacylase E2 L homeolog (dbt.L), BCATE2, BCKAD-E2, BCKADE2, D3Wsu60e, E2, E2B, E2b, im:7147214, zgc:103768

Protein level used designations for DBT

  • lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
  • dihydrolipoamide branched chain transacylase E2
  • BCKAD E2 subunit
  • E2 component of branched chain alpha-keto acid dehydrogenase complex
  • branched chain acyltransferase, E2 component
  • branched-chain alpha-keto acid dehydrogenase complex component E2
  • dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
  • dihydrolipoyl transacylase
  • dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
  • lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex
  • mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b)
  • BCKAD E2
  • BCKAD-E2
  • BCKADE2
  • branched-chain alpha-ketoacid dehydrogenase, E2 subunit
  • part of the BCKAD complex
  • que
  • mitochondrial branched-chain alpha-keto acid dihydrolipoyl acyltransferase
  • component of branched chain keto acid dehydrogenase complex
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