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DLST encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. Additionally we are shipping DLST Antibodies (29) and DLST Kits (4) and many more products for this protein.
Showing 8 out of 9 products:
heterozygous inactivation of a tricarboxylic acid (TCA) cycle enzyme, dihydrolipoamide S-succinyltransferase (Dlst), significantly delayed tumor onset in zebrafish without detectable effects on fish development
RNAi knockdown of DLST led to decreased cell viability and induction of apoptosis in human T-ALL cell lines
ATP consumption is demonstrated in respiration-impaired isolated and in situ neuronal somal mitochondria from transgenic mice that exhibit a 20-48% decrease in alpha-ketoglut (show DLD Proteins)arate dehydrogenase activity.
Association between late-onset Alzheimer disease shows strong linkage disequilibrium across the DLST locus.
DLST protein levels were decreased on pressure overload in wild-type mice, but levels were maintained in microRNA-146a knock-out mice.
ATP consumption is demonstrated in respiration-impaired isolated and in situ neuronal somal mitochondria from transgenic mice with a deficiency of dihydrolipoyl dehydrogenase (show DLD Proteins).
A reduction in the DLST subunit of alpha-ketoglutarate dehydrogenase (show alphaKGDHC Proteins) complex (KGDHC) alters the overall KGDHC activity and susceptibility to mitochondrial toxins and may contribute to the pathogenesis of neurodegenerative diseases.
This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene.
dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
, dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
, dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial-like
, 2-oxoglutarate dehydrogenase complex component E2
, dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex